{"id":15566,"date":"2023-11-16T13:04:07","date_gmt":"2023-11-16T12:04:07","guid":{"rendered":"https:\/\/www.laborberlin.com\/news\/neurobiostand-project-launched\/"},"modified":"2024-07-17T09:32:58","modified_gmt":"2024-07-17T07:32:58","slug":"neurobiostand-project-launched","status":"publish","type":"news","link":"https:\/\/www.laborberlin.com\/en\/news\/neurobiostand-project-launched\/","title":{"rendered":"NEuroBioStand project launched"},"content":{"rendered":"<div class=\"Module ImageText ImageText--imageText Background Background--transparent\" >\n    <div class=\"container\">\n        <div class=\"grid grid--vCenter grid--size12 grid--size6Tp grid--bigGaps\">\n            <div class=\"ImageText__imageColumn\">\n                <div class=\"ImageText__imageWrap\">\n                    \n    <picture\n        style=\"padding-top: 66.69921875%\"         class=\"Picture ImageText__image\"\n    >\n        <img decoding=\"async\"\n                src=\"\"\n                        data-src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2023\/11\/getty-images-WmmBVbiyuM0-unsplash-1024x683.jpg\"                class=\"lazyload Picture__image\"\n                alt=\"\"\n            title=\"getty-images-WmmBVbiyuM0-unsplash\"\/>\n\n        \n        <noscript>\n            <img decoding=\"async\" src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2023\/11\/getty-images-WmmBVbiyuM0-unsplash-1024x683.jpg\" alt=\"\" title=\"getty-images-WmmBVbiyuM0-unsplash\"\/>\n        <\/noscript>\n    <\/picture>\n\n                    <\/div>\n            <\/div>\n\n            <div class=\"ImageText__textWrap\">\n                \n                <h3>Neurofilament light chain from serum as a biomarker for nerve cell damage<\/h3>\n<p>Neurodegenerative diseases have a significant impact on patients&#8217; lives. Early and precise diagnosis in these cases can be particularly important for the quality of life of those affected. This is made possible, among other things, by the determination of neurofilament light chain (NfL) in serum, e.g. in ALS (amyotrophic lateral sclerosis) or frontotemporal dementia. The measurement of NfL is currently only possible in a few laboratories.<\/p>\n                \n\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<div class=\"Module Text Background Background--transparent\" >\n    <div class=\"container\">\n        \n\n                                <div class=\"Text__content Text__content--full\">\n                <h3><strong>What makes the determination so valuable as a routine parameter?<\/strong><\/h3>\n<p>The detection of NfL from serum only requires a standard blood sample for diagnosis. This can be done by any doctor and can help to provide a more targeted indication for a lumbar puncture if necessary. However, as the concentration of NfL in serum is much lower, a special, highly sensitive measuring method is required, the so-called Single Molecule Assay from Quanterix\u00ae.<\/p>\n<h3><strong>Why are uniform standards so important?<\/strong><\/h3>\n<p>PD Dr. med. P\u00e9ter K\u00f6rtv\u00e9lyessy, expert in biomarkers in neurology and project manager for innovative neurological developments at Labor Berlin, heads a working group of the EU-funded NEuroBioStand project (start: 01.10.2023). This has set itself the goal of introducing uniform standards for different neurological determination methods &#8211; including for NfL. The comparability of the different methods ensures that the measured value per method is the same in all laboratories. Such standardized tests avoid fundamental misdiagnoses &#8211; is it a fatal disease or a normal finding? &#8211; and thus ensure particularly reliable results for patients. For routine measurements, Labor Berlin takes part in so-called interlaboratory tests. For new, innovative biomarkers, such as NfL, these standards must first be defined. Labor Berlin will now provide active support in meeting the standards set for these new values and the new measurement methods.<\/p>\n<h3>\n<strong>What does this mean for healthcare in Germany?<\/strong><\/h3>\n<p>With the routine determination of neurofilament light chain from serum, Labor Berlin is one of the few clinical laboratories in the world that can offer the important biomarker neurofilament light chain (NfL) to all senders outside of research and under accredited conditions. Neurofilament Light Chain in serum has already become an important biomarker beyond neurology, e.g. in pediatrics, oncology or intensive care medicine.<\/p>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"Module TeaserColumns Background Background--transparent\" >\n    <div class=\"container\">\n        \n\n        \n                    <div class=\"TeaserColumns__list grid grid--size12  grid--size4T grid--size6Tp\">\n                                    <div class=\"TeaserColumns__item\">\n                                                    <span class=\"Topline TeaserColumns__topline\">SCIENTIFIC MANAGEMENT<\/span>\n                        \n                                                    <div class=\"TeaserColumns__image\">\n                                \n    <picture\n                class=\"Picture  Picture--hero\"\n    >\n        <img decoding=\"async\"\n                src=\"\"\n                        data-srcset=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-scaled.jpg 1745w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-768x1126.jpg 768w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-1047x1536.jpg 1047w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-1396x2048.jpg 1396w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-1600x2347.jpg 1600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-1024x1502.jpg 1024w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-800x1173.jpg 800w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-600x880.jpg 600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-400x587.jpg 400w\"                class=\"lazyload Picture__image\"\n                alt=\"\"\n            title=\"florian-klauer-mk7D-4UCfmg-unsplash\"\/>\n\n                    <div class=\"Picture__tooltip\">\n                <div class=\"Picture__tooltipIcon\">\u00a9<\/div>\n                <div class=\"Picture__tooltipContent\">\n                    florian-klauer-mk7D-4UCfmg-unsplash                <\/div>\n            <\/div>\n        \n        <noscript>\n            <img decoding=\"async\" src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2020\/06\/florian-klauer-mk7D-4UCfmg-unsplash-3200x4693.jpg\" alt=\"\" title=\"florian-klauer-mk7D-4UCfmg-unsplash\"\/>\n        <\/noscript>\n    <\/picture>\n\n                                <\/div>\n                        \n                                                    <p>PD Dr. med. Peter K\u00f6rtv\u00e9lyessy<br \/>\n<a href=\"mailto:Peter.Koertvelyessy@laborberlin.com\">Peter.Koertvelyessy@laborberlin.com <\/a><\/p>\n<p>&nbsp;<\/p>\n                        \n                                            <\/div>\n                                    <div class=\"TeaserColumns__item\">\n                                                    <span class=\"Topline TeaserColumns__topline\">PRESS CONTACT<\/span>\n                        \n                        \n                                                    <p>Annett Dauchert<br \/>\n<a href=\"mailto:presse@laborberlin.com\">presse@laborberlin.com<\/a><\/p>\n                        \n                                            <\/div>\n                                    <div class=\"TeaserColumns__item\">\n                                                    <span class=\"Topline TeaserColumns__topline\">PUBLICATION<\/span>\n                        \n                                                    <div class=\"TeaserColumns__image\">\n                                \n    <picture\n                class=\"Picture  Picture--hero\"\n    >\n        <img decoding=\"async\"\n                src=\"\"\n                        data-srcset=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-scaled.jpg 2560w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-768x513.jpg 768w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-1536x1025.jpg 1536w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-2048x1367.jpg 2048w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-1600x1068.jpg 1600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-1024x684.jpg 1024w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-800x534.jpg 800w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-600x401.jpg 600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-400x267.jpg 400w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-390x260.jpg 390w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-780x520.jpg 780w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-510x340.jpg 510w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-1020x680.jpg 1020w\"                class=\"lazyload Picture__image\"\n                alt=\"\"\n            title=\"bank-phrom-Tzm3Oyu_6sk-unsplash\"\/>\n\n                    <div class=\"Picture__tooltip\">\n                <div class=\"Picture__tooltipIcon\">\u00a9<\/div>\n                <div class=\"Picture__tooltipContent\">\n                    bank-phrom-Tzm3Oyu_6sk-unsplash                <\/div>\n            <\/div>\n        \n        <noscript>\n            <img decoding=\"async\" src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/bank-phrom-Tzm3Oyu_6sk-unsplash-3200x2136.jpg\" alt=\"\" title=\"bank-phrom-Tzm3Oyu_6sk-unsplash\"\/>\n        <\/noscript>\n    <\/picture>\n\n                                <\/div>\n                        \n                                                    <p>Here you can find a publication by PD Dr. med. Peter K\u00f6rtv\u00e9lyessy on the topic: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37770938\/\">Serum neurofilament light chain in COVID-19 and the influence of renal function<\/a><\/p>\n                        \n                                            <\/div>\n                                    <div class=\"TeaserColumns__item\">\n                                                    <span class=\"Topline TeaserColumns__topline\">PRESS RELEASE<\/span>\n                        \n                                                    <div class=\"TeaserColumns__image\">\n                                \n    <picture\n                class=\"Picture  Picture--hero\"\n    >\n        <img decoding=\"async\"\n                src=\"\"\n                        data-srcset=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-scaled.jpg 2560w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-768x514.jpg 768w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-1536x1028.jpg 1536w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-2048x1371.jpg 2048w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-1600x1071.jpg 1600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-1024x686.jpg 1024w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-800x536.jpg 800w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-600x402.jpg 600w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-400x268.jpg 400w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-390x260.jpg 390w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-510x340.jpg 510w\"                class=\"lazyload Picture__image\"\n                alt=\"\"\n            title=\"hello-i-m-nik-MAgPyHRO0AA-unsplash\"\/>\n\n        \n        <noscript>\n            <img decoding=\"async\" src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/02\/hello-i-m-nik-MAgPyHRO0AA-unsplash-3200x2142.jpg\" alt=\"\" title=\"hello-i-m-nik-MAgPyHRO0AA-unsplash\"\/>\n        <\/noscript>\n    <\/picture>\n\n                                <\/div>\n                        \n                                                    <p>You <a href=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2023\/11\/Pressemitteilung_LaborBerlin_NEuroBioStand_NfL.pdf\">can download<\/a> the press release here<\/p>\n<p>&nbsp;<\/p>\n                        \n                                            <\/div>\n                                    <div class=\"TeaserColumns__item\">\n                                                    <span class=\"Topline TeaserColumns__topline\">REQUIREMENTS NfL<\/span>\n                        \n                                                    <div class=\"TeaserColumns__image\">\n                                \n    <picture\n                class=\"Picture  Picture--hero\"\n    >\n        <img decoding=\"async\"\n                src=\"\"\n                        data-srcset=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/03\/IMM_Icon_30-Prozent-Hintergrund.png 472w, https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/03\/IMM_Icon_30-Prozent-Hintergrund-400x272.png 400w\"                class=\"lazyload Picture__image\"\n                alt=\"\"\n            title=\"Fachbereich Immunologie\"\/>\n\n        \n        <noscript>\n            <img decoding=\"async\" src=\"https:\/\/www.laborberlin.com\/wp-content\/uploads\/2021\/03\/IMM_Icon_30-Prozent-Hintergrund.png\" alt=\"\" title=\"Fachbereich Immunologie\"\/>\n        <\/noscript>\n    <\/picture>\n\n                                <\/div>\n                        \n                                                    <p>To request the determination of Neurofilament Light Chain, please use this request form:<\/p>\n                        \n                                                    \n                            <a href=\"\/wp-content\/uploads\/250613_IMM-Anfo-003-05_Neurofilament_2025_06_05.pdf\" class=\"TeaserColumns__more More\">PDF REQUEST FORM NfL<\/a>\n                                            <\/div>\n                            <\/div>\n            <\/div>\n<\/div>\n\n","protected":false},"featured_media":0,"template":"","class_list":["post-15566","news","type-news","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.7 - 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