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![Portrait von Prof. Dr. Malte Spielmann]( "Malte Spielmann_Charite_SabineGudath")
©Malte Spielmann_Charite_SabineGudath
Prof. Dr. Malte Spielmann takes over as Director of Human Genetics Department
02.01.26 | We are delighted to welcome Prof. Dr. Malte Spielmann as the new Director of the Human Genetics Department at Labor Berlin. At the same time, he has taken up the professorship for Medical Genetics and Human Genetics at Charité – Universitätsmedizin Berlin, where he heads the institute of the same name. Prof. Spielmann is a globally recognized expert on the genetic causes of rare diseases and specializes in deciphering congenital malformations.
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Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation
Christian Gaebler, Samad Kor, Kristina Allers, Michela Perotti, David Mwangi, Karolin Meixenberger, Kirsten Hanke, Timo Trenkner, Tom Kraus, Yequin Sha, Carmen Arentowicz, Stanley Odidika, Nikolai Grahn, Rachel Scheck, Naomi Perkins, Marion Pardons, Vanessa Igbokwe, Victor Corman, Thomas Burmeister, Olga Blau, Gülüstan Sürücü, Axel Pruß, Christian G. Schneider, Gerd Klausen, Jürgen Sauter, Florian Klein, Leif E. Sander, Jörg Hofmann, Lam Vuong, Lars Bullinger, Livius Penter, Henning Gruell, Daniel B. Reeves, Philipp Schommers, Angelique Hoelzemer, Martin Obermeier, Igor W. Blau, Thomas Schneider & Olaf Penack Nature 2025 Dec 1. doi: 10.1038/s41586-025-09893-0 Doi: 10.1038/s41586-025-09893-0 PMID: 41326734
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Frequency of synaptic antigen-specific CD4+ T cells in dementia is age-dependent but not correlated with cognitive impairment
Julius Hoffmann, Marie-Luise Machule, Jakob Kreye, Laura Stöffler, Péter Körtvelyessy, Maria Buthut, Rosa Rößling, Petra Bacher, Alexander Scheffold, Harald Prüss Immunity & Aeging 2025 Jun 19;22(1):23 Doi: 10.1186/s12979-025-00516-w PMID: 40537813
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Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies
Wendy A Szymczak, Anne Line Engsbro, Jan Gorm Lisby, Juan José González-López, Paul Granato, Nathan Ledeboer, Donna M Wolk, Stephen Young, Daniel D Rhoads, Yvan Caspar, Lisa Steed, Romney Humphries, Christopher Bielefeldt, Markus Hermanowski, Juana L de Diego, Hendrik Leibhan, Pau Boher, Carla Camprubí, Maria Orthodoxou, Ester Sala, Sarah Johnson, Martí Juanola-Falgarona, Davide Manissero, Johanna Bialas Journal of Clinical Microbiology 2025 Aug 13;63(8):e0198324 Doi: 10.1128/jcm.01983-24 PMID: 40643259
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Detection of autoantibodies against Interferon Type I in patients withautochthonous West Nile Virus encephalitis
Jan Braune, Lorenz Pechstein, Christian Meisel, Tim Meyer, Julia Melchert, Victor Max Corman, Christiana Franke, Thomas Schneider Brain, Behavior, & Immunity – Health 2025 Jul 30:48:101085 Doi: 10.1016/j.bbih.2025.101085 PMID: 40799617
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The expanding clinical utility of blood neurofilament light chain (bNfL): a multi-disciplinary diagnostic tool
Peter Körtvelyessy, Burak Arslan, Jonah Nietiet, Christoph Leithner, Petra Hühnchen, Wolfgang Böhmerle, Matthias Endres, Christoph J Ploner, Heiner Audebert, Katrin Hahn, Thomas Meyer, Andreas Lüschow, Claudia Weiss, Lisa-Valerie Biztan, Sebastian Spethmann, Adriaan J Graw, Nadine Unterwalder, Christian Meisel, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg, Laura Göschel Journal of the Neurological Sciences, Volume 478, 123669, November 15, 2025 Doi: 10.1016/j.jns.2025.123669 PMID: 40912227
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Soluble Urokinase Plasminogen Activator Receptor Predicts Survival and Hepatic Decompensation in Advanced Hepatocellular Carcinoma
Fabian Artusa, Sven Lamatsch, Minh Duc Phan, Burcin Özdirik, Hilmar Berger, Mara Egerer, Jana Knorr-Klocke, Janett Fischer, Rhea Veelken, Florian van Bömmel, Thomas Berg, Kai Kappert, Rudolf Tauber, Tobias Puengel, Cornelius Engelmann, Münevver Demir, Frank Tacke, Raphael Mohr Liver International 2025 Jun;45(6):e70121 Doi: 10.1111/liv.70121 PMID: 40317602
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Coordinated implementation of a conventional PCR assay to detect all Ebola and Marburg virus species in a European laboratory network
K C Heimsch, T Bleicker, T D Best, L D Presser, R Molenkamp, A J Jääskeläinen, A Milewska, J Šmahelová, C Baronti, S Pappa, I Tabain, R Cordeiro, G Marsili, K Huik, V Pinho Dos Reis, L Barzon, P Maes, C Drosten, V M Corman Journal of Clinical Virology 2025 Jun:178:105808 Doi: 10.1016/j.jcv.2025.105808 PMID: 40451100
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Serum neurofilament light chain and multimodal neuroprognostication after cardiac arrest – A retrospective cohort study
Constanze Czimmeck, Jens Nee, Carl Hinrichs, Christian Endisch, Péter Körtvélyessy, Christoph J Ploner, Christoph Leithner, Martin Kenda Resuscitation 2025 May 21:213:110650 Doi: 10.1016/j.resuscitation.2025.110650 PMID: 40409670
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Comparative evaluation of multimarker algorithms for early-stage HCC detection in multicenter prospective studies
Jinlin Hou, Thomas Berg, Arndt Vogel, Teerha Piratvisuth, Jörg Trojan, Enrico N De Toni, Masatoshi Kudo, Katarina Malinowsky, Peter Findeisen, Johannes Kolja Hegel, Wenzel Schöning, Kairat Madin, Konstantin Kroeniger, Henry Lik-Yuen Chan, Ashish Sharma; JHEP Reports 2024 Nov 8;7(2):101263, Doi: 10.1016/j.jhepr.2024.101263, PMID: 39897614
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Sysmex XN-Based Evaluation of the Diagnostic Performance of High-Fluorescent Cells From CSF as a Supportive Diagnostic Criterion in Neurological Diseases
Benedict Schwarz, Christopher Hardt, Katharina Friedrich, Monika Prpic, Anja Osterloh, Frank L Heppner, Klemens Ruprecht, Kai Kappert, Amir Jahic International Journal of Laboratory Medicine, 2025 March 20 Doi: 10.1111/ijlh.14466 PMID: 40112826
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