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Publikationen

 
Nachfolgend sind einige ausgewählte Publikationen aus dem Fachbereich Hämato-Onkologie aufgelistet.

2016

Ostendorf, B N, Hansmann, L, Ludwig, w-D, Dörken, B, Ratei, R, Westermann, J.: Durchflusszytometrische Immunphänotypisierung in der klinischen Diagnostik. Dtsch Med Wochenschr 2016; 141: 1569–1574

Neuendorff N R, Burmeister T, Dörken B, Westermann J: BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features. Annaly of hematology DOI 10.1007/s00277-016-2721-z

2014

Burmeister T, Gröger D, Bartels G, Trautmann H, Schwartz S, Lenz K, Tietze-Bürger C, Viardot A, Wäsch R, Horst HA, Reinhardt R, Gökbuget N, Hoelzer D, Kneba M, Brüggemann M: Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group. haematologica 2014; 99:e23-e25. PMID:24497567.

Türkmen S, Binder A, Gerlach A, Niehage S, Faber J, Melissari MT, Inandiklioglu N, Dörken B, Burmeister T: High prevalence of Immunoglobulin Light Chain Gene rearrangements as revealed by FISH in Multiple Myeloma and MGUS. Genes, Chromosomes and Cancer 2014;53:650-6. PMID: 24729354.

2013

Singh A, Schabath R, Ratei R, Stroux A, Klemke CD, Nebe T, Flörcken A, van Lessen A, Anagnostopoulos I, Dörken B, Ludwig WD, Pezzutto A, Westermann J. Peripheral blood sCD3- CD4+ T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma. Hematol Oncol. 2013 Jun 24. PMID:23798351

2012

Blau O: Molecular investigation of Ewing sarcoma: about detecting translocations. EMBO Molecular Medicine 2012;4:1-2 PMID: 22467249

Kroenlein H, Schwartz S, Reinhardt R, Rieder H, Molkentin M, Gökbuget N, Hoelzer D, Thiel E, Burmeister T. Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR. Genes Chromosomes Cancer. 2012;51:290-9. PMID: 22120970

Nguyen-Hoai T, Baldenhofer G, Ahmed MS, Pham-Duc M, Gries M, Lipp M, Dörken B, Pezzutto A, Westermann J. CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model. J Gene Med. 2012;14:128-37. PMID: 22228591

2011

Blau O.: Bone Marrow Microenviroment in the Pathogenesis of AML. In: Koschmieder S, ed. Myeloid Leukemia-Basic Mechanisms of Leukemogenesis. InTech, 2011

Blau O, Baldus CD, Hofmann WK, Thiel G, Nolte F, Burmeister T, Türkmen S, Benlasfer O, Schümann E, Sindram A, Molkentin M, Mundlos S, Keilholz U, Thiel E, Blau IW. Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts. Blood. 2011;118:5583-92. PMID: 21948175

Burmeister T, Gröger D, Kühn A, Hoelzer D, Thiel E, Reinhardt R. Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias. DNA Repair (Amst). 2011;10:1131-7. PMID: 21944569

Westermann J, Flörcken A, Willimsky G, van Lessen A, Kopp J, Takvorian A, Jöhrens K, Lukowsky A, Schönemann C, Sawitzki B, Pohla H, Frank R, Dörken B, Schendel DJ, Blankenstein T, Pezzutto A. Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study. Gene Ther. 2011;18354-63. PMID: 21068778

Schwartz S, Reisman A, Troke PF. (2011): The Efficacy of Voriconazole in the Treatment of 192 Fungal central nervous system infections - a retrospective analysis; Infection 2011, 39: 201-10. PMID: 21512792

Schwartz S, Vergoulidou M, Schreier E, Loddenkemper C, Reinwald M, Schmidt-Hieber M, Flegel WA, Thiel E, Schneider T. (2011): Norovirus gastroenteritis causes severe and lethal complications after chemotherapy and hematopoietic stem cell transplantation; Blood 2011, 117:5850-6. PMID: 21487110

Türkmen S, Riehn M, Klopocki E, Molkentin M, Reinhardt R, Burmeister T. A BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1. Genes Chromosomes Cancer. 2011;50(6):389-96. PMID: 21412927

Vergoulidou M, Krause L, Foerster MH, Thiel E, Schwartz S. (2011): Endogenous filamentous fungal endophthalmitis – single center survey in patients with acute leukaemia or post allogeneic stem cell transplantation and review of the literature; Mycoses 2011; 54: e704. PMID: 21605192

Westermann J, Flörcken A, Willimsky G, van Lessen A, Kopp J, Takvorian A, Jöhrens K, Lukowsky A, Schönemann C, Sawitzki B, Pohla H, Frank R, Dörken B, Schendel DJ, Blankenstein T, Pezzutto A. Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study. Gene Ther. 2011;18:354-63. PMID: 21068778

2010

Burmeister T, Gökbuget N, Schwartz S, Fischer L, Hubert D, Sindram A, Hoelzer D, Thiel E. Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia. Haematologica. 2010;95:241-6. PMID: 19713226

Hemmati PG, Müer A, Gillissen B, Overkamp T, Milojkovic A, Wendt J, Dörken B, Daniel PT. Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3. J Mol Med (Berl). 2010;88:609-22. PMID: 20419447

Gillissen B, Wendt J, Richter A, Richter A, Müer A, Overkamp T, Gebhardt N, Preissner R, Belka C, Dörken B, Daniel PT. Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.J Cell Biol. 2010 Mar 22;188(6):851-62. PMID: 20308427

Kaiser M, Lamottke B, Mieth M, Jensen MR, Quadt C, Garcia-Echeverria C, Atadja P, Heider U, von Metzler I, Türkmen S, Sezer O. Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma. Eur J Haematol. 2010;84:337-44. PMID: 20028416

le Coutre P, Reinke P, Neuhaus R, Trappe R, Ringel F, Lalancette M, Hemmati PG, Dörken B, Daniel PT. BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients. Eur J Haematol. 2010;84(1):26-33. PMID: 19799626

Schmidt-Hieber M, Blau IW, Richter G, Türkmen S, Bommer C, Thiel G, Neitzel H, Stroux A, Uharek L, Thiel E, Blau O. Cytogenetic studies in acute leukemia patients relapsing after allogeneic stem cell transplantation. Cancer Genet Cytogenet. 2010;198(2):135-43. PMID: 20362228

Schwartz S. Cerebral Aspergillus Infections and Meningitis. In Aspergillosis: From Diagnosis to Prevention (Hrsg. Pasqualotto AC). S. 835-52. Springer 2010.

2009

Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, Schneider B, Raff T, Reinhardt R, Gökbuget N, Hoelzer D, Thiel E, Marschalek R. The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group. Blood. 2009;113:4011-5. PMID: 19144982

Westermann J, Hecker AC, Flörcken A, Dörken B, Pezzutto A. Granulocyte macrophage-colony stimulating factor plus interleukin-2 plus alpha-interferon plus 5-fluorouracil in the treatment of metastatic renal cell cancer: induction of CD80/86+ T cells indicates adverse outcome. J Immunother. 2009;32:667-75. PMID: 19483643

 

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