• CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells

    Bunse M, Pfeilschifter J, Bluhm J, Zschummel M, Joedicke JJ, Wirges A, Stark H, Kretschmer V, Chmielewski M, Uckert W, Abken H, Westermann J, Rehm A, Höpken UE. Nature Communications. doi: 10.1038/s41467-020-20488-3. PMID: 33431832

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  • Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases

    Kappert K, Jahić A, Tauber R. Biomarkers. 2020 Dec;25(8):616-625. PMID: 32700561 DOI: 10.1080/1354750X.2020.1797880

  • Performance evaluation of the Roche Elecsys Anti-SARS-CoV-2 S immunoassay

    Riester E, Findeisen P, Hegel JK, Kabesch M, Ambrosch A, Rank CM, Pessl F, Laengin T, Niederhauser C.J Virol Methods. 2021 Aug 27:114271. Link: doi: 10.1016/j.jviromet.2021.114271.

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  • A Single dose of the Biontech/Pfizer BNT162b2 vaccine protected elderly residents from severe COVID-19 during a SARS-Coronavirus-2 outbreak in a senior citizen home in Germany.

    R. Schwarzer, S. D. Freys, N. Neuwinger, N. Beikert, B. Eberspaecher, A. Edelmann, M. Zuchowski, I. Slothouwer, A. Stein, K. Theil, P. Menzel, and J. Hofmann. Journal: Immunity, Inflammation and Disease, EPub ahead of Print

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  • Clinical outcome of older adults with acute myeloid Leukemia: An analysis of a large tertiary referral Center over two decades.

    Ihlow J, Gross S, Neuendorff NR, Busack L, Herneth A, Singh A, Schwarz M, Flörcken A, Anagnostopoulos I, Türkmen S, Burmeister T, Blau IW, Bullinger L, Westermann J. J Geriatr Oncol. 2021 May;12(4):540-549. doi: 10.1016/j.jgo.2020.11.001. Epub 2020 Nov 19. PMID: 33223482

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  • Outcome prediction by serum calprotectin in patients with COVID-19 in the emergency department

    Wolfgang Bauer 1, Eva Diehl-Wiesenecker 2, Jannis Ulke 3, Noa Galtung 2, Aleksandra Havelka 4, J Kolja Hegel 5, Rudolf Tauber 6, Rajan Somasundaram 2, Kai Kappert 6 J Infect. 2021 Apr;82(4):84-123. doi: 10.1016/j.jinf.2020.11.016 PMID: 33217473 PMCID: PMC7670934 DOI: 10.1016/j.jinf.2020.11.016

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  • Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia

    Andria Constantinou, Katarzyna Polak-Witka, Marios Tomazou, Anastasis Oulas, Varvara Kanti, Rolf Schwarzer, Johannes Helmuth, Anke Edelmann, Ulrike Blume-Peytavi, George M. Spyrou, Annika Vogt. Biomedicines 2021, 9(3), 266

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  • Immature Platelet Counts and Thrombopoietin Plasma Concentrations in Thrombocytopenic and Non-thrombocytopenic Preterm Infants

    Hannes Sallmon, Andreas Weimann, Christoph Bührer, Boris Metze, Christof Dame, Malte Cremer Front. Pediatr., 25 June 2021

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  • Precision medicine in myeloid malignancies

    Westermann J, Bullinger L. Seminars in Cancer Biology, 22 Apr 2021, DOI: 10.1016/j.semcancer.2021.03.034 PMID: 33895273

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  • Immunogenicity of COVID-19 Tozinameran Vaccination in Patients on Chronic Dialysis

    Schrezenmeier E, Bergfeld L, Hillus D, Lippert JD, Weber U, Tober-Lau P, Landgraf I, Schwarz T, Kappert K, Stefanski AL, Sattler A, Kotsch K, Dörner T, Sander LE, Budde K, Halleck F, Kurth F, Corman VM, Choi M. Front Immunol. 2021 Jun 30;12:690698.

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  • Glycosylation is a key in SARS-CoV-2 infection

    Reis CA, Tauber R, Blanchard V. J Mol Med (Berl). 2021 May 22:1–9. doi: 10.1007/s00109-021-02092-0. Epub ahead of print.

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  • Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

    Tatjana Schwarz, Pinkus Tober-Lau, David Hillus, Elisa T Helbig, Lena J Lippert, Charlotte Thibeault, Willi Koch, Irmgard Landgraf, Janine Michel, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Chantip Dang-Heine, Stefanie Kasper, Friederike Münn, Kai Kappert, Andreas Nitsche, Rudolf Tauber, Sein Schmidt, Piotr Kopankiewicz, Harald Bias, Joachim Seybold, Christof von Kalle, Terry C Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Victor M Corman, Florian Kurth Emerging Infectious Diseases 2021 Jun 8;27(8). doi: 10.3201/eid2708.211145

  • Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis.

    Yamaguchi Y, Saito A, Horie M, Aoki A, Micke P, Ohshima M, Kappert K. Odontology. 2021 Jun 14. doi: 10.1007/s10266-021-00625-0. Online ahead of print.

  • Mild COVID-19 despite autoantibodies to type I IFNs in Autoimmune-Polyendocrine-Syndrome Type 1 (APS-1)

    Christian Meisel*, Bengisu Akbil*, Tim Meyer, Erwin Lankes, Victor M. Corman, Olga Staudacher, Nadine Unterwalder, Uwe Kölsch, Christian Drosten, Marcus A. Mall, Tilmann Kallinich, Dirk Schnabel, Christine Goffinet and Horst von Bernuth. Journal of Clinical Investigation, 2021.

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  • Draft Genome Sequence of Mycobacteroides sp. Strain LB1, Isolated from the Sputum of a Cystic Fibrosis Patient

    Peter Menzel, Rolf Schwarzer, Johannes Helmuth and Inna Friesen, DOI: https://doi.org/10.1128/MRA.00797-20

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  • Estimating infectiousness throughout SARS-CoV-2 infection course

    View ORCID ProfileTerry C. Jones1,2,3,†, View ORCID ProfileGuido Biele4,5,†, View ORCID ProfileBarbara Mühlemann1,2, View ORCID ProfileTalitha Veith1,2, View ORCID ProfileJulia Schneider1,2, Jörn Beheim-Schwarzbach1, Tobias Bleicker1, Julia Tesch1, Marie Luisa Schmidt1, View ORCID ProfileLeif Erik Sander6, View ORCID ProfileFlorian Kurth6,7, View ORCID ProfilePeter Menzel8, View ORCID ProfileRolf Schwarzer8, View ORCID ProfileMarta Zuchowski8, Jörg Hofmann8, Andi Krumbholz9,10, Angela Stein8, View ORCID ProfileAnke Edelmann8, View ORCID ProfileVictor Max Corman1,2, View ORCID ProfileChristian Drosten1,2,* DOI: 10.1126/science.abi5273

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  • Mutation spectrum and polygenic score in German patients with familial hypercholesterolemia

    Lorenz Rieck 1, Frieda Bardey 1, Thomas Grenkowitz 2, Lars Bertram 3 4, Johannes Helmuth 5, Claudia Mischung 5, Joachim Spranger 1, Elisabeth Steinhagen-Thiessen 1, Thomas Bobbert 1, Ursula Kassner 1, Ilja Demuth 1 6; PMID: 32770674, DOI: 10.1111/cge.13826

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  • Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

    Aschenbrenner AC, Mouktaroudi M, Krämer B, Oestreich M, Antonakos N, Nuesch-Germano M, Gkizeli K, Bonaguro L, Reusch N, Baßler K, Saridaki M, Knoll R, Pecht T, Kapellos TS, Doulou S, Kröger C, Herbert M, Holsten L, Horne A, Gemünd ID, Rovina N, Agrawal S, Dahm K, van Uelft M, Drews A, Lenkeit L, Bruse N, Gerretsen J, Gierlich J, Becker M, Händler K, Kraut M, Theis H, Mengiste S, De Domenico E, Schulte-Schrepping J, Seep L, Raabe J, Hoffmeister C, ToVinh M, Keitel V, Rieke G, Talevi V, Skowasch D, Aziz NA, Pickkers P, van de Veerdonk FL, Netea MG, Schultze JL, Kox M, Breteler MMB, Nattermann J, Koutsoukou A, Giamarellos-Bourboulis EJ, Ulas T; German COVID-19 OMICSInitiative (DeCOI). 2021. Genome Med. 13:7.

  • SARS-CoV-2 in severe COVID-19 induces a TGF-b-dominated chronic immune response that does not target itself

    Ferreira-Gomes, M., A.Kruglov, P.Durek, F.Heinrich, C.Tizian, G.Heinz, A.Pascual-Reguant, Weijie Du, R.Mothes, C.Fan, S.Frischbutter, K.Habenicht, L.Budzinski, J.Ninnemann, P.Jani, G.Guerra, K.Lehmann, M.Matz, L.Ostendorf, L.Heiberger, H-D.Chang, S.Bauherr, M.Maurer, G.Schönrich, M.Raftery, T.Kallinich, M.Mall, S.Angermair, S.Treskatsch, T.Dörner, V.Corman, A.Diefenbach, H-D.Volk, S.Elezkurtaj, T.Winkler, J.Dong, A.Hauser, H.Radbruch, M.Witkowski, F.Melchers, A.Radbruch, and M-F.Mashreghi. 2021. Nature Communications. in press

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  • CD4+ T cells promote delayed B cell responses in theischemic brain after experimental stroke

    Weitbrecht L, Berchtold D, Zhang T, Jagdmann S, Dames C, Winek K, Meisel C,Meisel A. Brain Behav Immun. 2021Jan;91:601-614. doi: 10.1016/j.bbi.2020.09.029. Epub 2020 Sep 28. PMID:33002634.

  • External Validation of Five Scores to Predict Stroke-Associated Pneumonia and the Role of Selected Blood Biomarkers

    Hotter B, Hoffmann S, Ulm L, Meisel C, Bustamante A, Montaner J, Katan M, Smith CJ, Meisel A. Stroke. 2021Jan;52(1):325-330. doi: 10.1161/STROKEAHA.120.031884. Epub 2020 Dec 7. PMID:33280547.

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  • Head-to-head comparison of SARS-CoV-2 antigen-detecting rapid test with self-collected anterior nasal swab vs professional-collected nasopharyngeal swab.

    Lindner AK, Nikolai O, Kausch F, Wintel M, Hommes F, Gertler M, Krüger LJ, Gaeddert M, Tobian F, Lainati F, Köppel L, Seybold J, Corman VM, Drosten C, Hofmann J, Sacks JA, Mockenhaupt FP, Denkinger CM. Eur Respir J. 2020 Dec 10:2003961.

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  • Role of cell adhesion molecules for disease development of patients with and without COVID-19 in the emergency department.

    Bauer W, Ulke J, Galtung N, Strasser-Marsik LC, Neuwinger N, Tauber R, Somasundaram R, Kappert K. J Infect Dis. 2021 Apr 23;223(8):1497-1499. doi: 10.1093/infdis/jiab042.

  • Matter of Caution: Coagulation Parameters in COVID-19 Do Not Differ from Patients with Ruled-Out SARS-CoV-2 Infection in the Emergency Department.

    Bauer W, Galtung N, Neuwinger N, Kaufner L, Langer E, Somasundaram R, Tauber R, Kappert K. A TH Open. 2021 Feb 6;5(1):e43-e55. doi: 10.1055/s-0040-1722612.

  • Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus,produce effector cytokines, and invade the kidneys.

    Abdirama D, Tesch S, Grießbach AS, von Spee-Mayer C, Humrich JY, Stervbo U,Babel N, Meisel C, Alexander T, Biesen R, Bacher P, Scheffold A, Eckardt KU,Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Enghard P. Kidney Int.2021Jan;99(1):238-246. doi: 10.1016/j.kint.2020.05.051. PMID:32592813.

  • Novichok nerve agent poisoning

    CASE REPORT| VOLUME 397, ISSUE 10270, P249-252, JANUARY 16, 2021 David Steindl, MD Wolfgang Boehmerle, MD Roland Körner, MD Damaris Praeger, MD Marcel Haug, MD Jens Nee, MD et al. Show all authors Published:December 22, 2020DOI:https://doi.org/10.1016/S0140-6736(20)32644-1

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  • Enhancing the differentiation of pulmonary lymphoma and fungal pneumonia in hematological patients using texture analysis in 3-T MRI.

    Kim D, Elgeti T, Penzkofer T, Steffen IG, Jensen LJ, Schwartz S, Hamm B, Nagel SN. Eur Radiol. 2021 Feb;31(2):695-705. doi: 10.1007/s00330-020-07137-5. Epub 2020 Aug 21. PMID: 32822054 Free PMC article.

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  • Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis.

    Kantarjian HM, Hughes TP, Larson RA, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Boquimpani C, Pasquini R, Clark RE, Dubruille V, Flinn IW, Kyrcz-Krzemien S, Medras E, Zanichelli M, Bendit I, Cacciatore S, Titorenko K, Aimone P, Saglio G, Hochhaus A. Leukemia. 2021 Feb;35(2):440-453. doi: 10.1038/s41375-020-01111-2. Epub 2021 Jan 7. PMID: 33414482 Free PMC article.

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  • Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.

    Jiang S, Penack O, Terzer T, Schult D, Majer-Lauterbach J, Radujkovic A, Blau IW, Bullinger L, Müller-Tidow C, Dreger P, Luft T. Haematologica. 2021 Feb 1;106(2):446-453. doi: 10.3324/haematol.2019.238790. PMID: 31974195 Free PMC article.

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  • B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.

    Ihlow J, Michaelis E, Greuel S, Heynol V, Lehmann A, Radbruch H, Meinhardt J, Miller F, Herbst H, Corman VM, Westermann J, Bullinger L, Horst D, von Brünneck AC, Elezkurtaj S. Int J Infect Dis. 2021 Feb;103:628-635. doi: 10.1016/j.ijid.2020.12.078. Epub 2021 Jan 2. PMID: 33401036 Free PMC article.

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  • Impact of a specialised palliative care intervention in patients with advanced soft tissue sarcoma – a single-centre retrospective analysis.

    Brandes F, Striefler JK, Dörr A, Schmiester M, Märdian S, Koulaxouzidis G, Kaul D, Behzadi A, Thuss-Patience P, Ahn J, Pelzer U, Bullinger L, Flörcken A. BMC Palliat Care. 2021 Jan 14;20(1):16. doi: 10.1186/s12904-020-00702-1. PMID: 33446180 Free PMC article.

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  • Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication.

    Dai H, Penack O, Radujkovic A, Schult D, Majer-Lauterbach J, Blau IW, Bullinger L, Jiang S, Müller-Tidow C, Dreger P, Luft T. Bone Marrow Transplant. 2021 Jan 30. doi: 10.1038/s41409-020-01186-6. Online ahead of print. PMID: 33517355

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  • B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased.

    Ihlow J, Michaelis E, Greuel S, Heynol V, Lehmann A, Radbruch H, Meinhardt J, Miller F, Herbst H, Corman VM, Westermann J, Bullinger L, Horst D, von Brünneck AC, Elezkurtaj S. Int J Infect Dis. 2021 Feb;103:628-635. doi: 10.1016/j.ijid.2020.12.078. Epub 2021 Jan 2. PMID: 33401036 Free PMC article.

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  • CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin’s lymphoma and tumor-supportive follicular T helper cells.

    Bunse M, Pfeilschifter J, Bluhm J, Zschummel M, Joedicke JJ, Wirges A, Stark H, Kretschmer V, Chmielewski M, Uckert W, Abken H, Westermann J, Rehm A, Höpken UE. Nat Commun. 2021 Jan 11;12(1):240. doi: 10.1038/s41467-020-20488-3. PMID: 33431832 Free PMC article.

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  • Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia.

    Rapaport F, Neelamraju Y, Baslan T, Hassane D, Gruszczynska A, Robert de Massy M, Farnoud N, Haddox S, Lee T, Medina-Martinez J, Sheridan C, Thurmond A, Becker M, Bekiranov S, Carroll M, Moses Murdock H, Valk PJM, Bullinger L, D’Andrea R, Lowe SW, Neuberg D, Levine RL, Melnick A, Garrett-Bakelman FE. Leukemia. 2021 Feb 12. doi: 10.1038/s41375-021-01153-0. Online ahead of print. PMID: 33580203 No abstract available.

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  • Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin.

    Schmalbrock LK, Dolnik A, Cocciardi S, Sträng E, Theis F, Jahn N, Panina E, Blätte TJ, Herzig JK, Skambraks S, Rücker FG, Gaidzik VI, Paschka P, Fiedler W, Salih HR, Wulf GG, Schroeder T, Lübbert M, Schlenk RF, Thol F, Heuser M, Larson RA, Ganser A, Stunnenberg HG, Minucci S, Stone RM, Bloomfield CD, Döhner H, Döhner K, Bullinger L. Blood. 2021 Feb 17:blood.2020007626. doi: 10.1182/blood.2020007626. Online ahead of print. PMID: 33598693

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  • Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges.

    Herda S, Heimann A, Obermayer B, Ciraolo E, Althoff S, Ruß J, Grunert C, Busse A, Bullinger L, Pezzutto A, Blankenstein T, Beule D, Na IK. Int J Cancer. 2021 Feb 18. doi: 10.1002/ijc.33523. Online ahead of print. PMID: 33600609

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  • Serum cytokines and theirpredictive value in pulmonary involvement of systemic sclerosis

    Becker MO, Radic M, Schmidt K, Huscher D, Riedlinger A, Michelfelder M,Meisel C, Ewert R, Burmester GR, Riemekasten G. SarcoidosisVasc Diffuse Lung Dis. 2019;36(4):274-284. doi: 10.36141/svdld.v36i4.7612. Epub2019 May 1. PMID: 32476963; PMCID: PMC7247092.

  • IL-6 PlasmaLevels Correlate With Cerebral Perfusion Deficits and Infarct Sizes in StrokePatients Without Associated Infections.

    Hotter B, Hoffmann S, Ulm L, Meisel C, Fiebach JB, Meisel A. Front Neurol. 2019 Feb 15;10:83. doi:10.3389/fneur.2019.00083. PMID: 30828313; PMCID: PMC6384225.

  • Screening and treatment for tuberculosis in a cohort ofunaccompanied minor refugees in Berlin, Germany

    Thee S, Krüger R, von Bernuth H, Meisel C, Kölsch U, Kirchberger V,Feiterna-Sperling C. PLoS One. 2019 May21;14(5):e0216234. doi: 10.1371/journal.pone.0216234. PMID: 31112542; PMCID:PMC6528979.

  • Killer-like receptors and GPR56progressive expression defines cytokine production of human CD4+memory T cells.

    Truong KL, Schlickeiser S, Vogt K, Boës D, Stanko K, Appelt C, Streitz M,Grütz G, Stobutzki N, Meisel C, et al. Nat Commun. 2019 May 22;10(1):2263. doi:10.1038/s41467-019-10018-1. PMID: 31118448; PMCID: PMC6531457.

  • Biomarkers of immune capacity, infection andinflammation are associated with poor outcome and mortality after stroke – thePREDICT study

    Mengel A, Ulm L, Hotter B, Harms H, Piper SK, Grittner U, Montaner J, MeiselC, Meisel A, Hoffmann S. BMC Neurol. 2019 Jul 3;19(1):148. doi: 10.1186/s12883-019-1375-6.PMID: 31269910; PMCID: PMC6607590.

  • Clinical research assessment by flowcytometry of biomarkers for infectious stratification in an EmergencyDepartment

    Bourgoin P, Soliveres T, Ahriz D, Arnoux I, Meisel C, Unterwalder N, MorangePE, Michelet P, Malergue F, Markarian T. Biomark Med. 2019 Nov;13(16):1373-1386. doi: 10.2217/bmm-2019-0214.Epub 2019 Oct 16. PMID: 31617736.

  • Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis incritically ill patients (HEMICU): a prospective observational study protocol.

    Lachmann G, Knaak C, von Haefen C, Paeschke N, Meisel C, et al. BMJ Open. 2019 Oct 30;9(10):e032695. doi: 10.1136/bmjopen-2019-032695. PMID:31666276; PMCID: PMC6830715.

  • Current gaps in sepsis immunology: new opportunities for translational research

    Rubio I, Osuchowski MF, Shankar-Hari M, Skirecki T, Winkler MS, Lachmann G,La Rosée P, Monneret G, Venet F, Bauer M, Brunkhorst FM, Kox M, Cavaillon JM,Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Martin-Fernandez M, Almansa R,Martin-Loeches I, Torres A, Giamarellos-Bourboulis EJ, Girardis M, Cossarizza A,Netea MG, van der Poll T, Scherag A, Meisel C, Schefold JC, Bermejo-Martín JF. Lancet Infect Dis. 2019 Dec;19(12):e422-e436. doi:10.1016/S1473-3099(19)30567-5. Epub 2019 Oct 17. PMID: 31630991.

  • Daratumumab treatment for therapy-refractoryanti-CASPR2 encephalitis.

    Scheibe F, Ostendorf L, Reincke SM, Prüss H, von Brünneck AC, Köhnlein M,Alexander T, Meisel C, Meisel A. J Neurol. 2020 Feb;267(2):317-323. doi:10.1007/s00415-019-09585-6. Epub 2019 Oct 19. PMID: 31630242.

  • T Cell Impairment Is Predictive for a Severe Clinical Course in NEMODeficiency.

    Heller S, Kölsch U, Magg T, Krüger R, Scheuern A, Schneider H, Eichinger A,Wahn V, Unterwalder N, Lorenz M, Schwarz K, Meisel C, Schulz A, Hauck F, vonBernuth H. J Clin Immunol. 2020 Apr;40(3):421-434. doi:10.1007/s10875-019-00728-y. Epub 2020 Jan 21. PMID: 31965418.

  • Immune biomarker-basedenrichment in sepsis trials. Crit Care.

    Spinetti T, Meisel C, von Gunten S, Schefold JC. 2020 Feb 19;24(1):58. doi:10.1186/s13054-020-2774-1. PMID: 32075672; PMCID: PMC7029545.

  • Inflammatory and stress markers predicting pneumonia, outcome, and etiology inpatients with stroke: Biomarkers for predicting pneumonia, functional outcome,and death after stroke

    Hotter B, Hoffmann S, Ulm L, Montaner J, Bustamante A, Meisel C, Meisel A. Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692.doi: 10.1212/NXI.0000000000000692. PMID: 32098866; PMCID: PMC7051196.

  • Acute nicotine administration stimulatesciliary activity via α3β4 nAChR in the mouse trachea.

    Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A,Scholze P, Kummer W, Krasteva-Christ G. Int Immunopharmacol. 2020 Jul;84:106496. doi: 10.1016/j.intimp.2020.106496. Epub 2020 Apr 15. PMID:32304995.

  • Analysis of solubleinterleukin-2 receptor as CSF biomarker for neurosarcoidosis

    Otto C, Wengert O, Unterwalder N, Meisel C, Ruprecht K. NeurolNeuroimmunol Neuroinflamm. 2020 May 11;7(4):e725. doi:10.1212/NXI.0000000000000725. PMID: 32393650; PMCID: PMC7238895.

  • Impact of Key Nicotinic AChR Subunits on Post-Stroke Pneumococcal Pneumonia.

    Jagdmann S, Dames C, Berchtold D, Winek K, Weitbrecht L, Meisel A, Meisel C. Vaccines (Basel). 2020 May 28;8(2):253. doi: 10.3390/vaccines8020253. PMID:32481512; PMCID: PMC7349987.

  • Interaction of microglia withinfiltrating immune cells in the different phases of stroke.

    Berchtold D, Priller J, Meisel C, Meisel A. Brain Pathol. 2020Nov;30(6):1208-1218. doi: 10.1111/bpa.12911. Epub 2020 Nov 2. PMID: 33058417.

  • Presence of anti-neuronal antibodies in children with neurologicaldisorders beyond encephalitis.

    Nikolaus M, Meisel C, Kreye J, Prüss H, Reindl M, Kaindl AM, Schuelke M,Knierim E. Eur J Paediatr Neurol. 2020 Sep;28:159-166. doi:10.1016/j.ejpn.2020.07.004. Epub 2020 Jul 30. PMID: 32807683.

  • CD70Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman.

    Krüger R, Martin E, Dmytrus J, Feiterna-Sperling C, Meisel C, et al. Front Immunol. 2020 Aug 4;11:1593. doi: 10.3389/fimmu.2020.01593. PMID: 32849540; PMCID:PMC7417345.

  • SIGLEC1 (CD169) is a sensitive biomarker for thedeterioration of the clinical course in childhood systemic lupus erythematosus.

    Stuckrad SLV, Klotsche J, Biesen R, Lieber M, Thumfart J, Meisel C,Unterwalder N, Kallinich T. Lupus. 2020 Dec;29(14):1914-1925. doi: 10.1177/0961203320965699. Epub 2020 Oct20. PMID: 33081587; PMCID: PMC7684796.

  • SIGLEC1 (CD169) as a potential diagnostical screening marker for monogenic interferonopathies.

    Orak B, Ngoumou G, Ebstein F, Zieba B, Goetzke CC, Knierim E, Kaindl AM, Panzer A, Theophil M, Berns M, Krüger E, Meisel C, Unterwalder N, Kallinich T. Pediatr Allergy Immunol. 2020 Oct 25. doi:10.1111/pai.13400. Epub ahead of print. PMID: 33099809.

  • A case of neonatal onsetmultisystem inflammatory disease supporting a role of interleukin-1β in moyamoyasyndrome.

    Wohlrab F, Bauknecht C, Meisel C, Dreier JP. Neurol Neuroimmunol Neuroinflamm. 2020 Oct 27;8(1):e1-3. doi:10.1212/NXI.0000000000000910. PMID: 33109682.

  • Myositis-specific autoantibodies and their associated phenotypes in juveniledermatomyositis: data from a German cohort.

    Horn S, Minden K, Speth F, Schwarz T, Dressler F, Grösch N, Haas JP, Hinze C,Horneff G, Hospach A, Kallinich T, Klotsche J, Köstner K, Meisel C, et al. Clin Exp Rheumatol. 2020 Oct 29.PMID: 33124555.

  • Newborn Screening for SCID and Other SeverePrimary Immunodeficiency in the Polish-German Transborder Area: Experience From the First 14 Months of Collaboration.

    Giżewska M, Durda K, Winter T, Ostrowska I, Ołtarzewski M, Klein J,Blankenstein O, Romanowska H, Krzywińska-Zdeb E, Patalan MF, Bartkowiak E,Szczerba N, Seiberling S, Birkenfeld B, Nauck M, von Bernuth H, Meisel C, et al. Front Immunol. 2020 Oct 16;11:1948. doi:10.3389/fimmu.2020.01948. PMID: 33178177; PMCID: PMC7596351.

  • Transfer RNA fragments replace microRNA regulators of thecholinergic poststroke immune blockade.

    Winek K, Lobentanzer S, Nadorp B, Dubnov S, Dames C, Jagdmann S, Moshitzky G,Hotter B, Meisel C, et al. Proc Natl Acad Sci U S A. 2020 Dec22;117(51):32606-32616. doi: 10.1073/pnas.2013542117. Epub 2020 Dec 7. PMID:33288717; PMCID: PMC7768686.

  • CD4+ T cells promote delayed B cell responses in theischemic brain after experimental stroke.

    Weitbrecht L, Berchtold D, Zhang T, Jagdmann S, Dames C, Winek K, Meisel C, et al. Brain Behav Immun. 2021Jan;91:601-614. doi: 10.1016/j.bbi.2020.09.029. Epub 2020 Sep 28. PMID:33002634.

  • External Validation of Five Scores to Predict Stroke-Associated Pneumonia and the Role of Selected Blood Biomarkers

    Hotter B, Hoffmann S, Ulm L, Meisel C, et al. Stroke. 2021Jan;52(1):325-330. doi: 10.1161/STROKEAHA.120.031884. Epub 2020 Dec 7. PMID:33280547.

  • Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus,produce effector cytokines, and invade the kidneys.

    bdirama D, Tesch S, Grießbach AS, von Spee-Mayer C, Humrich JY, Stervbo U,Babel N, Meisel C, et al. Kidney Int. 2021Jan;99(1):238-246. doi: 10.1016/j.kint.2020.05.051. PMID:32592813.

  • Draft Genome Sequence of Mycobacteroides sp. Strain LB1, Isolated from the Sputum of a Cystic Fibrosis Patient

    Peter Menzel, Rolf Schwarzer, Johannes Helmuth, Inna Friesen

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  • Novichok nerve agent poisoning.

    Steindl D, Boehmerle W, Körner R, Praeger D, Haug M, Nee J, Schreiber A, Scheibe F, Demin K, Jacoby P, Tauber R, Hartwig S, Endres M, Eckardt KU. Lancet. 2020 Dec 22:S0140-6736(20)32644-1. doi: 10.1016/S0140-6736(20)32644-1. Epub ahead of print

  • Outcome prediction by serum calprotectin in patients with COVID-19 in the emergency department

    Bauer W, Diehl-Wiesenecker E, Ulke J; Galtung N; Havelka A, Hegel KJ, Tauber R, Somasundaram R, Kappert K J Infect. 2020 Nov 17:S0163-4453(20)30711-8. doi: 10.1016/j.jinf.2020.11.016.

  • Patients’ Perception of the Diagnosis of Malignancy, and the Overlap with Physicians’ Subjective Assessment in Pelvic Mass Patients. Results of a Multicentric, Prospective Pelvic Mass Study.

    Koch E, Torsten U, Mecke H et al. J Psychosomatic Obstetrics & Gynecology 2020, DOI: 10.1080/0167482X.2020.1850684.

  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

    Schulte-Schrepping J, Reusch N, Paclik D, Baßler K et al. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi:10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. PMID: 32810438; PMCID: PMC7405822.

  • Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis.

    Kramer F, Dernedde J, Mezheyeuski A, Tauber R, Micke P, Kappert K. Haematologica. 2020 Aug;105(8):2083-2094. doi: 10.3324/haematol.2019.226332.

  • Reversal of apixaban induced alterations in haemostasis by different coagulation factor concentrates in patients after hip or knee replacement surgery.

    Schmidt K, Krüger K, Langer E, et al. Blood Transfus. 2019;17(2):157-162. doi:10.2450/2018.0028-18

  • Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases.

    Kappert, K, Jahic, A., Tauber, R. Biomarkers DOI: 10.1080/1354750X.2020.1797880.

  • Pooling, room temperature and extended storage time increase the release of adult- specific biological response modifiers in platelet packages: A hidden risk for transfusion in neonates.

    Miriam Waubert de Puiseau, Lina K. Sciesielski, Oliver Meyer, Chiara-Aiyleen Badur, Helge Schönfeld, Rudolf Tauber, Axel Pruß and Christof Dame. Transfusion 2020 Apr 27. doi: 10.1111/trf.15827.

  • Use of Relative Ion Intensities for Enhanced Selectivity in a High Pressure Liquid Chromatography – Tandem Mass Spectrometry Method for Iohexol in Human Serum.

    Vincent J. T. Schweinsberg, Stefan Eckelt, Anna M. Schulz, Marcel Arlt, Marc Schumann, Markus van der Giet, Rudolf Tauber, Torsten Binscheck-Domaß, Peggy Kießling. Clinical Chemistry and Laboratory Medicine 58(5):709-718 (2020). doi: 10.1515/cclm-2019-1001.

  • GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity.

    Hauffe R, Stein V, Chudoba C, Flore T, Rath M, Ritter K, Schell M, Wardelmann K, Deubel S, Kopp JF, Schwarz M, Kappert K, Blüher M, Schwerdtle T, Kipp AP, Kleinridders A. JCI Insight. 2020 Jun 4;5(11):e136283. doi: 10.1172/jci.insight.136283.

  • Consolidation of clinical microbiology laboratories and introduction of transformative technologies

    Vandenberg, O., G.Durand, M.Hallin, A.Diefenbach, V.Gant, P.Murray, Z.Kozlakidis, and A.van Belkum. 2020. Clin Microbiol Rev. 33:e00057-19.

  • NK Cell Development in Times of Innate Lymphoid Cell Diversity

    Stokic-Trtica V, A.Diefenbach*, and C.S.N.Klose*. Front Immunol. 2020. 11:813. Published 2020 Jul 8. doi:10.3389/fimmu.2020.00813 (*Corresponding Author)

  • Innate lymphoid cell-epithelial cell modules sustain intestinal homeostasis

    Diefenbach, A., S.Gnafakis, and O.Shomrat. 2020. Immunity. 52:452-463.

  • Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

    Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 OMICS Initiative (DeCOI). 2020. Immunity. 53:1296-1314.

  • NK Cells Regulate CD8+ T Cell Mediated Autoimmunity

    Lang, P.A., S.Q.Crome, H.C.Xu, K.S.Lang, L.Chapatte, E.K. Deenick, M.Grusdat, A.A.Pandyra, V.I.Pozdeev, R.Wang, T.A. W.Holderried, H.Cantor, A.Diefenbach, A.R.Elford, D.R.McIlwain, M.Recher, D.Häussinger, T.W.Mak, and P.S.Ohashi. 2020. Frontiers in Cellular and Infection Microbiology. doi: 0.3389/fcimb.2020.00036

  • hirty years of VRE in Germany – “expect the unexpected“: The view from the National Reference Centre for Staphylococci and Enterococci

    Werner G, Neumann B, Weber RE, Kresken M, Wendt C, Bender JK; VRE study group. 2020. TDrug Resist Updat. 53:100732.

  • c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells

    Tizian, C., A.Lahmann, O.Hölsken, C.Cosovanu, M.Kofoed-Branzk, F.Heinrich, M.F.Mashreghi, A.Kruglov, A.Diefenbach, and C.Neumann. 2020. eLife. 9:e56774

  • Microbiota-induced tonic type I interferons instruct a poised basal state of dendritic cells. Cell

    Schaupp L, S.Muth, L.Rogell, M.Kofoed-Branzk, F.Melchior, S.Lienenklaus, S.C.Ganal-Vonarburg, M.Klein, F.Guendel, T.Hain, K.Schütze, U.Grundmann, V.Schmitt, M.Dorsch, J.Spanier, P.Tegtmeyer, T.Schwanz, S.Jäckel, C.Reinhardt, T.Bopp, S.Danckwardt, K.Mahnke, G.A.Heinz, M.F.Mashreghi, P.Durek, U.Kalinke, O.Kretz, T.B.Huber, S.Weiss, C.Wilhelm, A.J.Macpherson, H.Schild, A.Diefenbach1,*, H.C.Probst*. 2020. 181:1080-1096. 1Lead Senior Author; *equal contribution.

  • Group 3 innate lymphoid cells program a distinct subset of IL-22BP-producing dendritic cells demarcating solitary intestinal lymphoid tissues

    Guendel, F., M.Kofoed-Branzk, K.Gronke, C.Tizian, M.Witkowski, H-W.Cheng, G.A.Heinz, F.Heinrich, P.Durek, P.S.Norris, C.F.Ware, C.Ruedl, S.Herold, K.Pfeffer, T.Hehlgans, A.Waisman, B.Becher, A.D.Giannou S.Brachs, K.Ebert, Y.Tanriver, B.Ludewig, M-F.Mashreghi, A.A.Kruglov, and A.Diefenbach. 2020. Immunity. 53:1015-1032.

  • Daratumumab treatment for therapy-refractoryanti-CASPR2 encephalitis

    Scheibe F, Ostendorf L, Reincke SM, Prüss H, von Brünneck AC, Köhnlein M,Alexander T, Meisel C, Meisel A. J Neurol. 2020 Feb;267(2):317-323. doi:10.1007/s00415-019-09585-6. Epub 2019 Oct 19. PMID: 31630242.

  • T Cell Impairment Is Predictive for a Severe Clinical Course in NEMODeficiency

    Heller S, Kölsch U, Magg T, Krüger R, Scheuern A, Schneider H, Eichinger A,Wahn V, Unterwalder N, Lorenz M, Schwarz K, Meisel C, Schulz A, Hauck F, vonBernuth H. J Clin Immunol. 2020 Apr;40(3):421-434. doi:10.1007/s10875-019-00728-y. Epub 2020 Jan 21. PMID: 31965418.

  • Immune biomarker-basedenrichment in sepsis trials

    Spinetti T, Meisel C, von Gunten S, Schefold JC. Crit Care. 2020 Feb 19;24(1):58. doi:10.1186/s13054-020-2774-1. PMID: 32075672; PMCID: PMC7029545.

  • Inflammatory and stress markers predicting pneumonia, outcome, and etiology inpatients with stroke: Biomarkers for predicting pneumonia, functional outcome,and death after stroke

    Hotter B, Hoffmann S, Ulm L, Montaner J, Bustamante A, Meisel C, Meisel A. Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692.doi: 10.1212/NXI.0000000000000692. PMID: 32098866; PMCID: PMC7051196.

  • Acute nicotine administration stimulatesciliary activity via α3β4 nAChR in the mouse trachea

    Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A,Scholze P, Kummer W, Krasteva-Christ G. Int Immunopharmacol. 2020 Jul;84:106496. doi: 10.1016/j.intimp.2020.106496. Epub 2020 Apr 15. PMID:32304995.

  • Analysis of solubleinterleukin-2 receptor as CSF biomarker for neurosarcoidosis

    Otto C, Wengert O, Unterwalder N, Meisel C, Ruprecht K. NeurolNeuroimmunol Neuroinflamm. 2020 May 11;7(4):e725. doi:10.1212/NXI.0000000000000725. PMID: 32393650; PMCID: PMC7238895.

  • Impact of Key Nicotinic AChR Subunits on Post-Stroke Pneumococcal Pneumonia

    Jagdmann S, Dames C, Berchtold D, Winek K, Weitbrecht L, Meisel A, Meisel C. Vaccines (Basel). 2020 May 28;8(2):253. doi: 10.3390/vaccines8020253. PMID:32481512; PMCID: PMC7349987.

  • Presence of anti-neuronal antibodies in children with neurologicaldisorders beyond encephalitis

    Nikolaus M, Meisel C, Kreye J, Prüss H, Reindl M, Kaindl AM, Schuelke M,Knierim E. Eur J Paediatr Neurol. 2020 Sep;28:159-166. doi:10.1016/j.ejpn.2020.07.004. Epub 2020 Jul 30. PMID: 32807683.

  • CD70Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman

    Krüger R, Martin E, Dmytrus J, Feiterna-Sperling C, Meisel C, Unterwalder N,Kölsch U, Wahn V, Hofmann J, Korn P, Latour S, Boztug K, von Bernuth H. Front Immunol. 2020 Aug 4;11:1593. doi: 10.3389/fimmu.2020.01593. PMID: 32849540; PMCID:PMC7417345.

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  • SIGLEC1 (CD169) is a sensitive biomarker for thedeterioration of the clinical course in childhood systemic lupus erythematosus

    Stuckrad SLV, Klotsche J, Biesen R, Lieber M, Thumfart J, Meisel C,Unterwalder N, Kallinich T. Lupus. 2020 Dec;29(14):1914-1925. doi: 10.1177/0961203320965699. Epub 2020 Oct20. PMID: 33081587; PMCID: PMC7684796.

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  • SIGLEC1 (CD169) as a potential diagnostical screening marker for monogenic interferonopathies

    Orak B, Ngoumou G, Ebstein F, Zieba B, Goetzke CC, Knierim E, Kaindl AM, Panzer A, Theophil M, Berns M, Krüger E, Meisel C, Unterwalder N, Kallinich T. Pediatr Allergy Immunol. 2020 Oct 25. doi:10.1111/pai.13400. Epub ahead of print. PMID: 33099809.

  • A case of neonatal onsetmultisystem inflammatory disease supporting a role of interleukin-1β in moyamoyasyndrome

    Wohlrab F, Bauknecht C, Meisel C, Dreier JP. Neurol Neuroimmunol Neuroinflamm. 2020 Oct 27;8(1):e1-3. doi:10.1212/NXI.0000000000000910. PMID: 33109682.

  • Myositis-specific autoantibodies and their associated phenotypes in juveniledermatomyositis: data from a German cohort

    Horn S, Minden K, Speth F, Schwarz T, Dressler F, Grösch N, Haas JP, Hinze C,Horneff G, Hospach A, Kallinich T, Klotsche J, Köstner K, Meisel C, Niewerth M,Oommen PT, Schütz C, Weller-Heinemann F, Unterwalder N, Sengler C. Clin Exp Rheumatol. 2020 Oct 29.PMID: 33124555.

  • Newborn Screening for SCID and Other SeverePrimary Immunodeficiency in the Polish-German Transborder Area: Experience From the First 14 Months of Collaboration

    Giżewska M, Durda K, Winter T, Ostrowska I, Ołtarzewski M, Klein J,Blankenstein O, Romanowska H, Krzywińska-Zdeb E, Patalan MF, Bartkowiak E,Szczerba N, Seiberling S, Birkenfeld B, Nauck M, von Bernuth H, Meisel C,Bernatowska EA, Walczak M, Pac M. Front Immunol. 2020 Oct 16;11:1948. doi:10.3389/fimmu.2020.01948. PMID: 33178177; PMCID: PMC7596351.

  • Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade

    Winek K, Lobentanzer S, Nadorp B, Dubnov S, Dames C, Jagdmann S, Moshitzky G,Hotter B, Meisel C, Greenberg DS, Shifman S, Klein J, Shenhar-Tsarfaty S, MeiselA, Soreq H. Proc Natl Acad Sci U S A. 2020 Dec22;117(51):32606-32616. doi: 10.1073/pnas.2013542117. Epub 2020 Dec 7. PMID:33288717; PMCID: PMC7768686.

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  • Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system.

    Schwartz S, Cornely OA, Hamed K, Marty FM, Maertens J, Rahav G, Herbrecht R, Heinz WJ. Med Mycol. 2020 Jun 1;58(4):417-424. doi: 10.1093/mmy/myz103. PMID: 31613363 Free PMC article.

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  • Treatment of invasive fungal diseases in cancer patients-Revised 2019 Recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).

    Ruhnke M, Cornely OA, Schmidt-Hieber M, Alakel N, Boell B, Buchheidt D, Christopeit M, Hasenkamp J, Heinz WJ, Hentrich M, Karthaus M, Koldehoff M, Maschmeyer G, Panse J, Penack O, Schleicher J, Teschner D, Ullmann AJ, Vehreschild M, von Lilienfeld-Toal M, Weissinger F, Schwartz S. Mycoses. 2020 Jul;63(7):653-682. doi: 10.1111/myc.13082. Epub 2020 May 12. PMID: 32236989 The choice of the most appropriate antifungal treatment (AFT) depends on the fungal species suspected or identified, the patient’s risk factors (eg length and depth of granulocytopenia) and the expected side effects. …

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  • The role of bosutinib in the treatment of chronic myeloid leukemia.

    Gambacorti-Passerini C, le Coutre P, Piazza R. Future Oncol. 2020 Jan;16(2):4395-4408. doi: 10.2217/fon-2019-0555. Epub 2019 Dec 13. PMID: 31833784 Free article. Review.

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  • Single-cell analysis based dissection of clonality in myelofibrosis.

    Mylonas E, Yoshida K, Frick M, Hoyer K, Christen F, Kaeda J, Obenaus M, Noerenberg D, Hennch C, Chan W, Ochi Y, Shiraishi Y, Shiozawa Y, Zenz T, Oakes CC, Sawitzki B, Schwarz M, Bullinger L, le Coutre P, Rose-Zerilli MJJ, Ogawa S, Damm F. Nat Commun. 2020 Jan 7;11(1):73. doi: 10.1038/s41467-019-13892-x. PMID: 31911629 Free PMC article.

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  • Primary analysis of JUMP, a phase 3b, expanded-access study evaluating the safety and efficacy of ruxolitinib in patients with myelofibrosis, including those with low platelet counts.

    Al-Ali HK, Griesshammer M, Foltz L, Palumbo GA, Martino B, Palandri F, Liberati AM, le Coutre P, García-Hernández C, Zaritskey A, Tavares R, Gupta V, Raanani P, Giraldo P, Hänel M, Damiani D, Sacha T, Bouard C, Paley C, Tiwari R, Mannelli F, Vannucchi AM. Br J Haematol. 2020 Jun;189(5):888-903. doi: 10.1111/bjh.16462. Epub 2020 Feb 4. PMID: 32017044 Clinical Trial.

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  • High-risk additional chromosomal abnormalities at low blast counts herald death by CML.

    Hehlmann R, Voskanyan A, Lauseker M, Pfirrmann M, Kalmanti L, Rinaldetti S, Kohlbrenner K, Haferlach C, Schlegelberger B, Fabarius A, Seifarth W, Spieß B, Wuchter P, Krause S, Kolb HJ, Neubauer A, Hossfeld DK, Nerl C, Gratwohl A, Baerlocher GM, Burchert A, Brümmendorf TH, Hasford J, Hochhaus A, Saußele S, Baccarani M; SAKK and the German CML Study Group. Leukemia. 2020 Aug;34(8):2074-2086. doi: 10.1038/s41375-020-0826-9. Epub 2020 May 7. PMID: 32382082 Free PMC article.

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  • Increased tumor burden in patients with chronic myeloid leukemia after 36 months of imatinib discontinuation.

    Diral E, Mori S, Antolini L, Abruzzese E, Le Coutre P, Martino B, Pungolino E, Elena C, Bergamaschi M, Assouline S, Di Bona E, Gozzini A, Andrade-Campos M, Stagno F, Iurlo A, Pirola A, Fontana D, Petiti J, Bonanomi ML, Crivori P, Piazza R, Fava C, Gambacorti-Passerini C. Blood. 2020 Nov 5;136(19):2237-2240. doi: 10.1182/blood.2019004371. PMID: 32518953 No abstract available.

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  • Bosutinib for pretreated patients with chronic phase chronic myeloid leukemia: primary results of the phase 4 BYOND study.

    Hochhaus A, Gambacorti-Passerini C, Abboud C, Gjertsen BT, Brümmendorf TH, Smith BD, Ernst T, Giraldo-Castellano P, Olsson-Strömberg U, Saussele S, Bardy-Bouxin N, Viqueira A, Leip E, Russell-Smith TA, Leone J, Rosti G, Watts J, Giles FJ; BYOND Study Investigators. Leukemia. 2020 Aug;34(8):2125-2137. doi: 10.1038/s41375-020-0915-9. Epub 2020 Jun 22. PMID: 32572189 Free PMC article. Clinical Trial.

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  • Early molecular response in East African Philadelphia chromosome-positive chronic myeloid leukaemia patients treated with Imatinib and barriers to access treatment.

    Henke O, Mapendo PJ, Mkwizu EW, le Coutre P. Ecancermedicalscience. 2020 Aug 18;14:1089. doi: 10.3332/ecancer.2020.1089. eCollection 2020. PMID: 33014131 Free PMC article.

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  • Combination therapy with Olaratumab/doxorubicin in advanced or metastatic soft tissue sarcoma -a single-Centre experience.

    Striefler JK, Brandes F, Baur A, Pfitzner BM, Kaul D, Rau D, Dörr A, Schmiester M, Koulaxouzidis G, Bullinger L, Märdian S, Flörcken A. BMC Cancer. 2020 Jan 29;20(1):68. doi: 10.1186/s12885-020-6551-y. PMID: 31996176 Free PMC article.

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  • Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition.

    Greiner J, Götz M, Hofmann S, Schrezenmeier H, Wiesneth M, Bullinger L, Döhner H, Schneider V. Cancer Immunol Immunother. 2020 Apr;69(4):629-640. doi: 10.1007/s00262-020-02490-2. Epub 2020 Feb 4. PMID: 32020256

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  • Single-cell analysis based dissection of clonality in myelofibrosis.

    Mylonas E, Yoshida K, Frick M, Hoyer K, Christen F, Kaeda J, Obenaus M, Noerenberg D, Hennch C, Chan W, Ochi Y, Shiraishi Y, Shiozawa Y, Zenz T, Oakes CC, Sawitzki B, Schwarz M, Bullinger L, le Coutre P, Rose-Zerilli MJJ, Ogawa S, Damm F. Nat Commun. 2020 Jan 7;11(1):73. doi: 10.1038/s41467-019-13892-x. PMID: 31911629 Free PMC article.

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  • Functional Classification of TP53 Mutations in Acute Myeloid Leukemia.

    Dutta S, Pregartner G, Rücker FG, Heitzer E, Zebisch A, Bullinger L, Berghold A, Döhner K, Sill H. Cancers (Basel). 2020 Mar 10;12(3):637. doi: 10.3390/cancers12030637. PMID: 32164171 Free PMC article.

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  • Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.

    Tausch E, Schneider C, Robrecht S, Zhang C, Dolnik A, Bloehdorn J, Bahlo J, Al-Sawaf O, Ritgen M, Fink AM, Eichhorst B, Kreuzer KA, Tandon M, Humphrey K, Jiang Y, Schary W, Bullinger L, Mertens D, Lurà MP, Kneba M, Döhner H, Fischer K, Hallek M, Stilgenbauer S. Blood. 2020 Jun 25;135(26):2402-2412. doi: 10.1182/blood.2019004492. PMID: 32206772

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  • Netboost: Boosting-supported Network Analysis Improves High-Dimensional Omics Prediction in Acute Myeloid Leukemia and Huntington’s Disease.

    Schlosser P, Knaus J, Schmutz M, Dohner K, Plass C, Bullinger L, Claus R, Binder H, Lubbert M, Schumacher M. IEEE/ACM Trans Comput Biol Bioinform. 2020 May 3;PP. doi: 10.1109/TCBB.2020.2983010. Online ahead of print. PMID: 32365034

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  • Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.

    Yusuf RZ, Saez B, Sharda A, van Gastel N, Yu VWC, Baryawno N, Scadden EW, Acharya S, Chattophadhyay S, Huang C, Viswanathan V, S’aulis D, Cobert J, Sykes DB, Keibler MA, Das S, Hutchinson JN, Churchill M, Mukherjee S, Lee D, Mercier F, Doench J, Bullinger L, Logan DJ, Schreiber S, Stephanopoulos G, Rizzo WB, Scadden DT. Blood. 2020 Sep 10;136(11):1303-1316. doi: 10.1182/blood.2019001808. PMID: 32458004

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  • Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.

    Lang KM, Harrison KL, Williamson PR, Huntly BJP, Ossenkoppele G, Geissler J, Bereczky T, Hernández-Rivas JM, Chevrou-Séverac H, Goodbody R, Schulze-Rath R, Bullinger L. Trials. 2020 May 27;21(1):437. doi: 10.1186/s13063-020-04384-1. PMID: 32460828 Free PMC article.

    zur Publikation
  • Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia.

    Becker H, Pfeifer D, Ihorst G, Pantic M, Wehrle J, Rüter BH, Bullinger L, Hackanson B, Germing U, Kuendgen A, Platzbecker U, Döhner K, Ganser A, Hagemeijer A, Wijermans PW, Döhner H, Duyster J, Lübbert M. Ann Hematol. 2020 Jul;99(7):1551-1560. doi: 10.1007/s00277-020-04082-7. Epub 2020 Jun 6. PMID: 32504186 Free PMC article. Clinical Trial.

    zur Publikation
  • Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells.

    Raffel S, Klimmeck D, Falcone M, Demir A, Pouya A, Zeisberger P, Lutz C, Tinelli M, Bischel O, Bullinger L, Thiede C, Flörcken A, Westermann J, Ehninger G, Ho AD, Müller-Tidow C, Gu Z, Herrmann C, Krijgsveld J, Trumpp A, Hansson J. Blood. 2020 Sep 24;136(13):1507-1519. doi: 10.1182/blood.2019003654. PMID: 32556243

    zur Publikation
  • Endothelial damage and dysfunction in acute graft-versus-host disease.

    Cordes S, Mokhtari Z, Bartosova M, Mertlitz S, Riesner K, Shi Y, Mengwasser J, Kalupa M, McGeary A, Schleifenbaum J, Schrezenmeier J, Bullinger L, Diaz-Ricart M, Palomo M, Carrreras E, Beutel G, Schmitt CP, Beilhack A, Penack O. Haematologica. 2020 Jul 16. doi: 10.3324/haematol.2020.253716. Online ahead of print. PMID: 32675225

    zur Publikation
  • Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients.

    Lauber C, Correia N, Trumpp A, Rieger MA, Dolnik A, Bullinger L, Roeder I, Seifert M. Sci Rep. 2020 Jul 29;10(1):12761. doi: 10.1038/s41598-020-69691-8. PMID: 32728112 Free PMC article.

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  • A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial.

    Janssen M, Schäkel U, Djuka Fokou C, Krisam J, Stermann J, Kriegsmann K, Haberbosch I, Novotny JP, Weber S, Vehreschild M, Bornhäuser M, Bullinger L, Schmitt M, Liebregts T, Dreger P, Lorenz HM, Plaszczyca A, Bartenschlager R, Müller B, Kräusslich HG, Halama N, Jäger D, Schlenk RF, Leo A, Meuer S, Weigand MA, Motsch J, Merle U, Denkinger CM, Müller-Tidow C. Trials. 2020 Oct 6;21(1):828. doi: 10.1186/s13063-020-04735-y. PMID: 33023671 Free PMC article.

    zur Publikation
  • The long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.

    Grasedieck S, Ruess C, Krowiorz K, Lux S, Pochert N, Schwarzer A, Klusmann JH, Jongen-Lavrencic M, Herold T, Bullinger L, Pollack JR, Rouhi A, Kuchenbauer F. Haematologica. 2020 Sep 1;105(9):e448-453. doi: 10.3324/haematol.2019.235291. PMID: 33054061 Free PMC article. No abstract available.

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  • Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.

    In’t Hout FEM, Gerritsen M, Bullinger L, Van der Reijden BA, Huls G, Vellenga E, Jansen JH. Haematologica. 2020 Sep 1;105(9):e454-457. doi: 10.3324/haematol.2019.232827. PMID: 33054062 Free PMC article. No abstract available.

    zur Publikation
  • Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.

    Tausch E, Beck P, Schlenk RF, Jebaraj BJ, Dolnik A, Yosifov DY, Hillmen P, Offner F, Janssens A, Babu GK, Grosicki S, Mayer J, Panagiotidis P, McKeown A, Gupta IV, Skorupa A, Pallaud C, Bullinger L, Mertens D, Döhner H, Stilgenbauer S. Haematologica. 2020 Oct 1;105(10):2440-2447. doi: 10.3324/haematol.2019.229161. PMID: 33054084 Free PMC article.

    zur Publikation
  • TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.

    Schmiester M, Dolnik A, Kornak U, Pfitzner B, Hummel M, Treue D, Hartmann A, Agaimy A, Weyerer V, Lekaj A, Brakemeier S, Peters R, Öllinger R, Märdian S, Bullinger L, Striefler JK, Flörcken A. J Pathol Clin Res. 2021 Jan;7(1):3-9. doi: 10.1002/cjp2.187. Epub 2020 Nov 12. PMID: 33180365 Free PMC article.

    zur Publikation
  • Clinical outcome of older adults with acute myeloid Leukemia: An analysis of a large tertiary referral Center over two decades.

    Ihlow J, Gross S, Neuendorff NR, Busack L, Herneth A, Singh A, Schwarz M, Flörcken A, Anagnostopoulos I, Türkmen S, Burmeister T, Blau IW, Bullinger L, Westermann J. J Geriatr Oncol. 2020 Nov 19:S1879-4068(20)30493-8. doi: 10.1016/j.jgo.2020.11.001. Online ahead of print. PMID: 33223482

    zur Publikation
  • Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.

    Reimann M, Schrezenmeier JF, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Masswig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA. Blood. 2020 Nov 24:blood.2020005244. doi: 10.1182/blood.2020005244. Online ahead of print. PMID: 33232972

    zur Publikation
  • Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.

    Jayavelu AK, Schnöder TM, Perner F, Herzog C, Meiler A, Krishnamoorthy G, Huber N, Mohr J, Edelmann-Stephan B, Austin R, Brandt S, Palandri F, Schröder N, Isermann B, Edlich F, Sinha AU, Ungelenk M, Hübner CA, Zeiser R, Rahmig S, Waskow C, Coldham I, Ernst T, Hochhaus A, Jilg S, Jost PJ, Mullally A, Bullinger L, Mertens PR, Lane SW, Mann M, Heidel FH. Nature. 2020 Dec;588(7836):157-163. doi: 10.1038/s41586-020-2968-3. Epub 2020 Nov 25. PMID: 33239784

    zur Publikation
  • Genomic heterogeneity in core-binding factor acute myeloid leukemia and its clinical implication.

    Jahn N, Terzer T, Sträng E, Dolnik A, Cocciardi S, Panina E, Corbacioglu A, Herzig J, Weber D, Schrade A, Götze K, Schröder T, Lübbert M, Wellnitz D, Koller E, Schlenk RF, Gaidzik VI, Paschka P, Rücker FG, Heuser M, Thol F, Ganser A, Benner A, Döhner H, Bullinger L, Döhner K. Blood Adv. 2020 Dec 22;4(24):6342-6352. doi: 10.1182/bloodadvances.2020002673. PMID: 33351131 Free PMC article.

    zur Publikation
  • Gene Expression Profiling Predicts Sensitivity of Chronic Lymphocytic Leukemia Cells to Dasatinib.

    Blätte TJ, Machnicki MM, Glodkowska-Mrowka E, Dolnik A, Karp M, Karczmarczyk A, Giannopoulos K, Bullinger L, Stoklosa T. Hemasphere. 2020 Dec 16;5(1):e514. doi: 10.1097/HS9.0000000000000514. eCollection 2021 Jan. PMID: 33354656 Free PMC article. No abstract available.

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  • Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial.

    Kapp-Schwoerer S, Weber D, Corbacioglu A, Gaidzik VI, Paschka P, Krönke J, Theis F, Rücker FG, Teleanu MV, Panina E, Jahn N, Herzig J, Kubanek L, Schrade A, Göhring G, Fiedler W, Kindler T, Schroeder T, Mayer KT, Lübbert M, Wattad M, Götze KS, Horst HA, Koller E, Wulf G, Schleicher J, Bentz M, Krauter J, Bullinger L, Krzykalla J, Benner A, Schlenk RF, Thol F, Heuser M, Ganser A, Döhner H, Döhner K. Blood. 2020 Dec 24;136(26):3041-3050. doi: 10.1182/blood.2020005998. PMID: 33367545

    zur Publikation
  • Clinical outcome of older adults with acute myeloid Leukemia: An analysis of a large tertiary referral Center over two decades.

    Ihlow J, Gross S, Neuendorff NR, Busack L, Herneth A, Singh A, Schwarz M, Flörcken A, Anagnostopoulos I, Türkmen S, Burmeister T, Blau IW, Bullinger L, Westermann J. J Geriatr Oncol. 2020 Nov 19

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  • Sex-specific metabolic and functional differences in human umbilical vein endothelial cells from twin pairs.

    Lorenz M, Blaschke B, Benn A, Hammer E, Witt E, Kirwan J, Fritsche-Guenther R, Gloaguen Y, Bartsch C, Vietzke A, Kramer F, Kappert K, Brunner P, Nguyen HG, Dreger H, Stangl K, Knaus P, Stangl V. Atherosclerosis. 2019 Dec;291:99-106. doi: 10.1016/j.atherosclerosis.2019.10.007.

  • Age-dependent diagnostic accuracy of clinical scoring systems and D-dimer levels in the diagnosis of pulmonary embolism with computed tomography pulmonary angiography (CTPA).

    Nagel SN, Steffen IG, Schwartz S, Hamm B, Elgeti T. Eur Radiol. 2019 Sep;29(9):4563-4571. doi: 10.1007/s00330-019-06039-5. Epub 2019 Feb 19. PMID: 30783786

    zur Publikation
  • Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung.

    Djureinovic D, Pontén V, Landelius P, Al Sayegh S, Kappert K, Kamali-Moghaddam M, Micke P, Ståhle E. BMC Cancer. 2019 Jul 29;19(1):741. doi: 10.1186/s12885-019-5943-3.

  • Innate Lymphoid Cells and Cancer at Border Surfaces With the Environment

    Mattiola, I., and A.Diefenbach. 2019. Semin Immunol. 41:101278

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari CT, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman DA, Bogdan C, Borger JG, Borsellino G, Boulais PE, Bradford JA, Brenner D, Brinkman RR, Brooks AES, Busch DH, Büscher M, Bushnell TP, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell SL, Casola S, Cassatella MA, Cavani A, Celada A, Chatenoud L, Chattopadhyay PK, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo FS, Cook L, Cooke A, Cooper AM, Corbett AJ, Cosma A, Cosmi L, Coulie PG, Cumano A, Cvetkovic L, Dang VD, Dang-Heine C, Davey MS, Davies D, De Biasi S, Del Zotto G, Dela Cruz GV, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo JP, Diefenbach A, et al. 2019. Eur J Immunol. 49:1457–1973.

  • Interleukin-22 protects intestinal stem cells against genotoxic stress

    Gronke, K., P.P.Hernández, J.Zimmermann, C.S.N.Klose, M.Kofoed-Branzk, F.Guendel, M.Witkowski, C.Tizian, L. Amann, F.Schumacher, H.Glatt, A.Triantafyllopoulou, and A.Diefenbach. 2019. Nature. 566:249-253.

  • Serum cytokines and theirpredictive value in pulmonary involvement of systemic sclerosis

    Becker MO, Radic M, Schmidt K, Huscher D, Riedlinger A, Michelfelder M,Meisel C, Ewert R, Burmester GR, Riemekasten G. SarcoidosisVasc Diffuse Lung Dis. 2019;36(4):274-284. doi: 10.36141/svdld.v36i4.7612. Epub2019 May 1. PMID: 32476963; PMCID: PMC7247092.

  • IL-6 PlasmaLevels Correlate With Cerebral Perfusion Deficits and Infarct Sizes in StrokePatients Without Associated Infections

    Hotter B, Hoffmann S, Ulm L, Meisel C, Fiebach JB, Meisel A. Front Neurol.2019 Feb 15;10:83. doi:10.3389/fneur.2019.00083. PMID: 30828313; PMCID: PMC6384225.

  • Screening and treatment for tuberculosis in a cohort ofunaccompanied minor refugees in Berlin, Germany

    Thee S, Krüger R, von Bernuth H, Meisel C, Kölsch U, Kirchberger V,Feiterna-Sperling C. PLoS One. 2019 May21;14(5):e0216234. doi: 10.1371/journal.pone.0216234. PMID: 31112542; PMCID:PMC6528979.

  • Killer-like receptors and GPR56progressive expression defines cytokine production of human CD4+memory T cells

    Truong KL, Schlickeiser S, Vogt K, Boës D, Stanko K, Appelt C, Streitz M,Grütz G, Stobutzki N, Meisel C, Iwert C, Tomiuk S, Polansky JK, Pascher A, BabelN, Stervbo U, Sauer I, Gerlach U, Sawitzki B. Nat Commun. 2019 May 22;10(1):2263. doi:10.1038/s41467-019-10018-1. PMID: 31118448; PMCID: PMC6531457.

  • Biomarkers of immune capacity, infection andinflammation are associated with poor outcome and mortality after stroke

    Mengel A, Ulm L, Hotter B, Harms H, Piper SK, Grittner U, Montaner J, MeiselC, Meisel A, Hoffmann S. thePREDICT study. BMC Neurol. 2019 Jul 3;19(1):148. doi: 10.1186/s12883-019-1375-6.PMID: 31269910; PMCID: PMC6607590.

  • Clinical research assessment by flowcytometry of biomarkers for infectious stratification in an EmergencyDepartment

    Bourgoin P, Soliveres T, Ahriz D, Arnoux I, Meisel C, Unterwalder N, MorangePE, Michelet P, Malergue F, Markarian T. Biomark Med. 2019 Nov;13(16):1373-1386. doi: 10.2217/bmm-2019-0214.Epub 2019 Oct 16. PMID: 31617736.

  • Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis incritically ill patients (HEMICU): a prospective observational study protocol

    Lachmann G, Knaak C, von Haefen C, Paeschke N, Meisel C, Nyvlt P, SchusterFS, Piper SK, Kruppa J, Vorderwülbecke G, Balzer F, La Rosée P, Schenk T,Unterwalder N, Kölsch U, Lachmann N, Akyüz L, Brunkhorst FM, Volk HD, Keh D,Spies C. BMJ Open. 2019 Oct 30;9(10):e032695. doi: 10.1136/bmjopen-2019-032695. PMID:31666276; PMCID: PMC6830715.

  • Current gaps in sepsis immunology: new opportunities for translational research

    Rubio I, Osuchowski MF, Shankar-Hari M, Skirecki T, Winkler MS, Lachmann G,La Rosée P, Monneret G, Venet F, Bauer M, Brunkhorst FM, Kox M, Cavaillon JM,Uhle F, Weigand MA, Flohé SB, Wiersinga WJ, Martin-Fernandez M, Almansa R,Martin-Loeches I, Torres A, Giamarellos-Bourboulis EJ, Girardis M, Cossarizza A,Netea MG, van der Poll T, Scherag A, Meisel C, Schefold JC, Bermejo-Martín JF. Lancet Infect Dis. 2019 Dec;19(12):e422-e436. doi:10.1016/S1473-3099(19)30567-5. Epub 2019 Oct 17. PMID: 31630991.

  • Underfilling of vacuum blood collection tubes leads to increased lactate dehydrogenase activity in serum and heparin plasma samples.

    Neuwinger N, Meyer Zum Büschenfelde D, Tauber R, Kappert K. Clin Chem Lab Med. 2019 Oct 30

  • Automated sample pretreatment für the analysis of synthetic cannabinoids in urine with LC-MS/MS.

    Stefan Eckelt, Simon Christopher Maaß, Carsten Mang. Poster MSACL September 2019, Salzburg.

  • A novel high pressure liquid chromatography (HPLC) – tandem mass spectrometry (MS/MS) method for the measurement of iohexol in human serum.

    Vincent Schweinsberg, Stefan Eckelt, Anna Schulz, Marcel Arlt, Marc Schumann, Markus van der Giet, Rudolf Tauber, Torsten Binscheck-Domaß, Peggy Kießling. Posterpreis der 16. Jahrestagung der DGKL (2019)

  • Pulmonary arterial remodelling by deficiency of peroxisome proliferator-activated receptor-γ in murine vascular smooth muscle cells occurs independently of obesity-related pulmonary hypertension.

    Caglayan E, Trappiel M, Behringer A, Berghausen EM, Odenthal M, Wellnhofer E, Kappert K. Respir Res. 2019 Feb 27;20(1):42. doi: 10.1186/s12931-019-1003-4.

  • PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.

    Bastian L, Schroeder MP, Eckert C, Schlee C, Tanchez JO, Kämpf S, Wagner DL, Schulze V, Isaakidis K, Lázaro-Navarro J, Hänzelmann S, James AR, Ekici A, Burmeister T, Schwartz S, Schrappe M, Horstmann M, Vosberg S, Krebs S, Blum H, Hecht J, Greif PA, Rieger MA, Brüggemann M, Gökbuget N, Neumann M, Baldus CD. Leukemia. 2019 Aug;33(8):1895-1909. doi: 10.1038/s41375-019-0430-z. Epub 2019 Mar 6. PMID: 30842609

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  • Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.

    Schroeder MP, Bastian L, Eckert C, Gökbuget N, James AR, Tanchez JO, Schlee C, Isaakidis K, Häupl B, Baum K, Migueles Lozano OA, Kouidri K, Pan KT, Urlaub H, Schwartz S, Burmeister T, von Stackelberg A, Hoelzer D, Pfeiffer H, Rieger MA, Göllner S, Oellerich T, Horstman M, Schrappe M, Wolf J, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Neumann M, Baldus CD. Sci Rep. 2019 Mar 12;9(1):4188. doi: 10.1038/s41598-019-40786-1. PMID: 30862934 Free PMC article. Clinical Trial.

    zur Publikation
  • Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial.

    Bastidas A, de la Serna J, El Idrissi M, Oostvogels L, Quittet P, López-Jiménez J, Vural F, Pohlreich D, Zuckerman T, Issa NC, Gaidano G, Lee JJ, Abhyankar S, Solano C, Perez de Oteyza J, Satlin MJ, Schwartz S, Campins M, Rocci A, Vallejo Llamas C, Lee DG, Tan SM, Johnston AM, Grigg A, Boeckh MJ, Campora L, Lopez-Fauqued M, Heineman TC, Stadtmauer EA, Sullivan KM; ZOE-HSCT Study Group Collaborators. JAMA. 2019 Jul 9;322(2):123-133. doi: 10.1001/jama.2019.9053. PMID: 31287523 Free PMC article. Clinical Trial.

    zur Publikation
  • Recombinant Zoster Vaccine Significantly Reduces the Impact on Quality of Life Caused by Herpes Zoster in Adult Autologous Hematopoietic Stem Cell Transplant Recipients: A Randomized Placebo-Controlled Trial (ZOE-HSCT).

    Curran D, Matthews S, Rowley SD, Young JH, Bastidas A, Anagnostopoulos A, Barista I, Chandrasekar PH, Dickinson M, El Idrissi M, Heras I, Milliken ST, Monserrat Coll J, Navarro Matilla MB, Oostvogels L, Piątkowska-Jakubas B, Quiel D, Sabry W, Schwartz S, Selleslag DLD, Sullivan KM, Theunissen K, Yegin ZA, Yeh SP, Zaja F, Szer J; ZOE-HSCT Study group collaborators. Biol Blood Marrow Transplant. 2019 Dec;25(12):2474-2481. doi: 10.1016/j.bbmt.2019.07.036. Epub 2019 Aug 5. PMID: 31394276 Free article. Clinical Trial.

    zur Publikation
  • Comparison of minimal residual disease levels in bone marrow and peripheral blood in adult acute lymphoblastic leukemia.

    Kotrova M, Volland A, Kehden B, Trautmann H, Ritgen M, Wäsch R, Faul C, Viardot A, Schwartz S, Baldus CD, Gökbuget N, Brüggemann M. Leukemia. 2020 Apr;34(4):1154-1157. doi: 10.1038/s41375-019-0599-1. Epub 2019 Oct 22. PMID: 31641191 No abstract available.

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  • Diagnostic Performance and Reliability of Non-Enhanced Imaging Characterization Quotients for the Differentiation of Infectious and Malignant Pulmonary Nodules in Hematological Patients Using 3T MRI.

    Nagel SN, Kim D, Wylutzki T, Steffen IG, Schwartz S, Penzkofer T, Hamm B, Elgeti T. Rofo. 2020 Apr;192(4):327-334. doi: 10.1055/a-1005-7424. Epub 2019 Oct 24. PMID: 31648350 Free article. English.

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  • Patient-reported outcomes in the phase 3 BFORE trial of bosutinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia.

    Cortes JE, Gambacorti-Passerini C, Deininger MW, Mauro MJ, Chuah C, Kim DW, Milojkovic D, le Coutre P, Garcia-Gutierrez V, Crescenzo R, Mamolo C, Reisman A, Hochhaus A, Brümmendorf TH; BFORE Study Investigators. J Cancer Res Clin Oncol. 2019 Jun;145(6):1589-1599. doi: 10.1007/s00432-019-02894-3. Epub 2019 Apr 15. PMID: 30989330 Clinical Trial.

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  • Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in patients with myelofibrosis.

    Durrant ST, Nagler A, Guglielmelli P, Lavie D, le Coutre P, Gisslinger H, Chuah C, Maffioli M, Bharathy S, Dong T, Wroclawska M, Lopez JM. Haematologica. 2019 Dec;104(12):e551-e554. doi: 10.3324/haematol.2018.209965. Epub 2019 May 9. PMID: 31073072 Free PMC article. Clinical Trial. No abstract available.

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  • Cost Effectiveness of the Third-Generation Tyrosine Kinase Inhibitor (TKI) Ponatinib, vs. Second-Generation TKIs or Stem Cell Transplant, as Third-Line Treatment for Chronic-Phase Chronic Myeloid Leukemia.

    Hirt C, Iannazzo S, Chiroli S, McGarry LJ, le Coutre P, Stenke L, Dahlén T, Lipton JH. Appl Health Econ Health Policy. 2019 Aug;17(4):555-567. doi: 10.1007/s40258-019-00489-0. PMID: 31168745

    zur Publikation
  • HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells.

    Nyambura LW, Muñoz AA, le Coutre P, Walden P. Sci Rep. 2019 Oct 1;9(1):14029. doi: 10.1038/s41598-019-50341-7. PMID: 31575892 Free PMC article.

    zur Publikation
  • Ponatinib in the Treatment of Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Leukemia: Recommendations of a German Expert Consensus Panel with Focus on Cardiovascular Management.

    Saussele S, Haverkamp W, Lang F, Koschmieder S, Kiani A, Jentsch-Ullrich K, Stegelmann F, Pfeifer H, La Rosée P, Goekbuget N, Rieger C, Waller CF, Franke GN, le Coutre P, Kirchmair R, Junghanss C. Acta Haematol. 2020;143(3):217-231. doi: 10.1159/000501927. Epub 2019 Oct 7. PMID: 31590170 Free PMC article. Review.

    zur Publikation
  • Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure.

    Hughes TP, Mauro MJ, Cortes JE, Minami H, Rea D, DeAngelo DJ, Breccia M, Goh YT, Talpaz M, Hochhaus A, le Coutre P, Ottmann O, Heinrich MC, Steegmann JL, Deininger MWN, Janssen JJWM, Mahon FX, Minami Y, Yeung D, Ross DM, Tallman MS, Park JH, Druker BJ, Hynds D, Duan Y, Meille C, Hourcade-Potelleret F, Vanasse KG, Lang F, Kim DW. N Engl J Med. 2019 Dec 12;381(24):2315-2326. doi: 10.1056/NEJMoa1902328. PMID: 31826340 Free PMC article. Clinical Trial.

    zur Publikation
  • A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia.

    Döhner H, Müller-Tidow C, Lübbert M, Fiedler W, Krämer A, Westermann J, Bug G, Schlenk RF, Krug U, Goeldner RG, Hilbert J, Taube T, Ottmann OG. Br J Haematol. 2019 May;185(3):583-587. doi: 10.1111/bjh.15563. Epub 2018 Nov 19. PMID: 30450591 Clinical Trial. No abstract available.

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  • Randomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine.

    Schlenk RF, Weber D, Herr W, Wulf G, Salih HR, Derigs HG, Kuendgen A, Ringhoffer M, Hertenstein B, Martens UM, Grießhammer M, Bernhard H, Krauter J, Girschikofsky M, Wolf D, Lange E, Westermann J, Koller E, Kremers S, Wattad M, Heuser M, Thol F, Göhring G, Haase D, Teleanu V, Gaidzik V, Benner A, Döhner K, Ganser A, Paschka P, Döhner H. Leukemia. 2019 Aug;33(8):1923-1933. doi: 10.1038/s41375-019-0395-y. Epub 2019 Feb 6. PMID: 30728457 Free PMC article. Clinical Trial.

    zur Publikation
  • Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.

    Christen F, Hoyer K, Yoshida K, Hou HA, Waldhueter N, Heuser M, Hills RK, Chan W, Hablesreiter R, Blau O, Ochi Y, Klement P, Chou WC, Blau IW, Tang JL, Zemojtel T, Shiraishi Y, Shiozawa Y, Thol F, Ganser A, Löwenberg B, Linch DC, Bullinger L, Valk PJM, Tien HF, Gale RE, Ogawa S, Damm F. Blood. 2019 Mar 7;133(10):1140-1151. doi: 10.1182/blood-2018-05-852822. Epub 2019 Jan 4. PMID: 30610028

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  • Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.

    Jutzi JS, Basu T, Pellmann M, Kaiser S, Steinemann D, Sanders MA, Hinai ASA, Zeilemaker A, Bojtine Kovacs S, Koellerer C, Ostendorp J, Aumann K, Wang W, Raffoux E, Cassinat B, Bullinger L, Schlegelberger B, Valk PJM, Pahl HL. Blood. 2019 Apr 18;133(16):1766-1777. doi: 10.1182/blood-2018-09-875047. Epub 2019 Feb 12. PMID: 30755419 Free PMC article.

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  • IDH2 inhibition: another piece to the puzzle.

    Bullinger L. Blood. 2019 Feb 14;133(7):625-626. doi: 10.1182/blood-2018-12-891481. PMID: 30765493 No abstract available.

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  • Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.

    Herrlinger U, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Sabel M, Hau P, Kortmann RD, Krex D, Grauer O, Goldbrunner R, Schnell O, Bähr O, Uhl M, Seidel C, Tabatabai G, Kowalski T, Ringel F, Schmidt-Graf F, Suchorska B, Brehmer S, Weyerbrock A, Renovanz M, Bullinger L, Galldiks N, Vajkoczy P, Misch M, Vatter H, Stuplich M, Schäfer N, Kebir S, Weller J, Schaub C, Stummer W, Tonn JC, Simon M, Keil VC, Nelles M, Urbach H, Coenen M, Wick W, Weller M, Fimmers R, Schmid M, Hattingen E, Pietsch T, Coch C, Glas M; Neurooncology Working Group of the German Cancer Society. Lancet. 2019 Feb 16;393(10172):678-688. doi: 10.1016/S0140-6736(18)31791-4. Epub 2019 Feb 14. PMID: 30782343 Clinical Trial.

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  • Analysis of the CDK4/6 Cell Cycle Pathway in Leiomyosarcomas as a Potential Target for Inhibition by Palbociclib.

    Böhm MJ, Marienfeld R, Jäger D, Mellert K, von Witzleben A, Brüderlein S, Wittau M, von Baer A, Schultheiss M, Mayer-Steinacker R, Rücker FG, Möller P, Bullinger L, Barth TFE. Sarcoma. 2019 Jan 21;2019:3914232. doi: 10.1155/2019/3914232. eCollection 2019. PMID: 30804704 Free PMC article.

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  • NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.

    Sasca D, Szybinski J, Schüler A, Shah V, Heidelberger J, Haehnel PS, Dolnik A, Kriege O, Fehr EM, Gebhardt WH, Reid G, Scholl C, Theobald M, Bullinger L, Beli P, Kindler T. Blood. 2019 May 23;133(21):2305-2319. doi: 10.1182/blood-2018-12-889725. Epub 2019 Feb 27. PMID: 30814062

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  • Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

    Basheer F, Giotopoulos G, Meduri E, Yun H, Mazan M, Sasca D, Gallipoli P, Marando L, Gozdecka M, Asby R, Sheppard O, Dudek M, Bullinger L, Döhner H, Dillon R, Freeman S, Ottmann O, Burnett A, Russell N, Papaemmanuil E, Hills R, Campbell P, Vassiliou GS, Huntly BJP. J Exp Med. 2019 Apr 1;216(4):966-981. doi: 10.1084/jem.20181276. Epub 2019 Mar 19. PMID: 30890554 Free PMC article.

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  • Venetoclax resistance and acquired BCL2 mutations in chronic lymphocytic leukemia.

    Tausch E, Close W, Dolnik A, Bloehdorn J, Chyla B, Bullinger L, Döhner H, Mertens D, Stilgenbauer S. Haematologica. 2019 Sep;104(9):e434-e437. doi: 10.3324/haematol.2019.222588. Epub 2019 Apr 19. PMID: 31004028 Free PMC article. No abstract available.

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  • IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.

    Scheffold A, Jebaraj BMC, Tausch E, Bloehdorn J, Ghia P, Yahiaoui A, Dolnik A, Blätte TJ, Bullinger L, Dheenadayalan RP, Li L, Schneider C, Chen SS, Chiorazzi N, Dietrich S, Seiffert M, Tannheimer S, Döhner H, Mertens D, Stilgenbauer S. Blood. 2019 Aug 8;134(6):534-547. doi: 10.1182/blood.2018881029. Epub 2019 Apr 22. PMID: 31010847

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  • New Targeted Agents in Acute Myeloid Leukemia: New Hope on the Rise.

    Bohl SR, Bullinger L, Rücker FG. Int J Mol Sci. 2019 Apr 23;20(8):1983. doi: 10.3390/ijms20081983. PMID: 31018543 Free PMC article. Review.

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  • Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation.

    Cocciardi S, Dolnik A, Kapp-Schwoerer S, Rücker FG, Lux S, Blätte TJ, Skambraks S, Krönke J, Heidel FH, Schnöder TM, Corbacioglu A, Gaidzik VI, Paschka P, Teleanu V, Göhring G, Thol F, Heuser M, Ganser A, Weber D, Sträng E, Kestler HA, Döhner H, Bullinger L, Döhner K. Nat Commun. 2019 May 2;10(1):2031. doi: 10.1038/s41467-019-09745-2. PMID: 31048683 Free PMC article.

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  • Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer.

    Penter L, Dietze K, Ritter J, Lammoglia Cobo MF, Garmshausen J, Aigner F, Bullinger L, Hackstein H, Wienzek-Lischka S, Blankenstein T, Hummel M, Dornmair K, Hansmann L. Oncoimmunology. 2019 Mar 24;8(6):e1586409. doi: 10.1080/2162402X.2019.1586409. eCollection 2019. PMID: 31069154 Free PMC article.

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  • Cytotoxic Effects of Rabbit Anti-thymocyte Globulin Preparations on Primary Human Thymic Epithelial Cells.

    Kaebisch EM, Cho MY, Oh YS, Olfe LI, Szyska M, Becker SC, Reinke P, Volk HD, Gillissen B, Bullinger L, Thiel A, Na IK. Transplantation. 2019 Nov;103(11):2234-2244. doi: 10.1097/TP.0000000000002799. PMID: 31205263

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  • Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.

    Jakobsen JS, Laursen LG, Schuster MB, Pundhir S, Schoof E, Ge Y, d’Altri T, Vitting-Seerup K, Rapin N, Gentil C, Jendholm J, Theilgaard-Mönch K, Reckzeh K, Bullinger L, Döhner K, Hokland P, Fitzgibbon J, Porse BT. Sci Adv. 2019 Jul 10;5(7):eaaw4304. doi: 10.1126/sciadv.aaw4304. eCollection 2019 Jul. PMID: 31309149 Free PMC article.

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  • Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.

    Doescher J, Weissinger SE, Schönsteiner SS, Lisson C, Bullinger L, Barth TF, Leithäuser F, Mueller-Richter U, Laban S, Hoffmann TK, Möller P, Lennerz JK, Schuler PJ. Immunotherapy. 2019 Oct;11(14):1193-1203. doi: 10.2217/imt-2019-0041. Epub 2019 Aug 29. PMID: 31462115 Clinical Trial.

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  • Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML).

    Agrawal M, Schwarz P, Giaimo BD, Bedzhov I, Corbacioglu A, Weber D, Gaidzik VI, Jahn N, Rücker FG, Schroeder T, Kindler T, Wattad M, Götze K, Lübbert M, Salwender H, Ringhoffer M, Lange E, Koller E, Thol F, Heuser M, Ganser A, Bullinger L, Paschka P, Döhner H, Geiger H, Borggrefe T, Döhner K, Oswald F. Leukemia. 2020 Feb;34(2):630-634. doi: 10.1038/s41375-019-0551-4. Epub 2019 Aug 28. PMID: 31462736 Free PMC article. No abstract available.

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  • Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.

    Edelmann J, Holzmann K, Tausch E, Saunderson EA, Jebaraj BMC, Steinbrecher D, Dolnik A, Blätte TJ, Landau DA, Saub J, Estenfelder S, Ibach S, Cymbalista F, Leblond V, Delmer A, Bahlo J, Robrecht S, Fischer K, Goede V, Bullinger L, Wu CJ, Mertens D, Ficz G, Gribben JG, Hallek M, Döhner H, Stilgenbauer S. Haematologica. 2020 May;105(5):1379-1390. doi: 10.3324/haematol.2019.217307. Epub 2019 Aug 29. PMID: 31467127 Free PMC article.

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  • Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.

    Weller J, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Hau P, Krex D, Grauer O, Goldbrunner R, Bähr O, Uhl M, Seidel C, Tabatabai G, Brehmer S, Bullinger L, Galldiks N, Schaub C, Kebir S, Stummer W, Simon M, Fimmers R, Coch C, Glas M, Herrlinger U, Schäfer N. Lancet Oncol. 2019 Oct;20(10):1444-1453. doi: 10.1016/S1470-2045(19)30502-9. Epub 2019 Sep 2. PMID: 31488360 Clinical Trial.

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  • Genotyping of circulating tumor DNA in cholangiocarcinoma reveals diagnostic and prognostic information.

    Ettrich TJ, Schwerdel D, Dolnik A, Beuter F, Blätte TJ, Schmidt SA, Stanescu-Siegmund N, Steinacker J, Marienfeld R, Kleger A, Bullinger L, Seufferlein T, Berger AW. Sci Rep. 2019 Sep 13;9(1):13261. doi: 10.1038/s41598-019-49860-0. PMID: 31519967 Free PMC article.

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  • Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group.

    Rücker FG, Agrawal M, Corbacioglu A, Weber D, Kapp-Schwoerer S, Gaidzik VI, Jahn N, Schroeder T, Wattad M, Lübbert M, Koller E, Kindler T, Götze K, Ringhoffer M, Westermann J, Fiedler W, Horst HA, Greil R, Schroers R, Mayer K, Heinicke T, Krauter J, Schlenk RF, Thol F, Heuser M, Ganser A, Bullinger L, Paschka P, Döhner H, Döhner K. Blood. 2019 Nov 7;134(19):1608-1618. doi: 10.1182/blood.2019001425. PMID: 31554635 Free article.

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  • Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).

    Meyer T, Jahn N, Lindner S, Röhner L, Dolnik A, Weber D, Scheffold A, Köpff S, Paschka P, Gaidzik VI, Heckl D, Wiese S, Ebert BL, Döhner H, Bullinger L, Döhner K, Krönke J. Leukemia. 2020 Feb;34(2):404-415. doi: 10.1038/s41375-019-0578-6. Epub 2019 Oct 1. PMID: 31576005 Free PMC article.

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  • Clonal hematopoiesis in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.

    Arends CM, Weiss M, Christen F, Eulenberg-Gustavus C, Rousselle A, Kettritz R, Eckardt KU, Chan W, Hoyer K, Frick M, Bullinger L, Bieringer M, Schreiber A, Damm F. Haematologica. 2020 Jun;105(6):e264-e267. doi: 10.3324/haematol.2019.223305. Epub 2019 Oct 3. PMID: 31582546 Free PMC article. No abstract available.

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  • Allogeneic hematopoietic cell transplantation improves outcome of adults with t(6;9) acute myeloid leukemia: results from an international collaborative study.

    Kayser S, Hills RK, Luskin MR, Brunner AM, Terré C, Westermann J, Menghrajani K, Shaw C, Baer MR, Elliott MA, Perl AE, Ráčil Z, Mayer J, Zak P, Szotkowski T, de Botton S, Grimwade D, Mayer K, Walter RB, Krämer A, Burnett AK, Ho AD, Platzbecker U, Thiede C, Ehninger G, Stone RM, Röllig C, Tallman MS, Estey EH, Müller-Tidow C, Russell NH, Schlenk RF, Levis MJ. Haematologica. 2020 Jan;105(1):161-169. doi: 10.3324/haematol.2018.208678. Epub 2019 Apr 19. PMID: 31004014 Free PMC article.

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  • Challenges in the systematic toxicological analysis of drugs and drugs of abuse (DoA)

    Peggy Kießling, Ludmila Mut, Christoph Köhler, Torsten Binscheck-Domaß, Thomas Gro-bosch. Poster Global Innovation Summit July 2019, Shimadzu.

  • Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.

    James AR, Schroeder MP, Neumann M, Bastian L, Eckert C, Gökbuget N, Tanchez JO, Schlee C, Isaakidis K, Schwartz S, Burmeister T, von Stackelberg A, Rieger MA, Göllner S, Horstman M, Schrappe M, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Akalin A, Baldus CD. J Hematol Oncol. 2019 Jan 14;12(1):8. doi: 10.1186/s13045-018-0692-3. PMID: 30642353 Free PMC article.

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  • Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO).

    Ruhnke M, Behre G, Buchheidt D, Christopeit M, Hamprecht A, Heinz W, Heussel CP, Horger M, Kurzai O, Karthaus M, Löffler J, Maschmeyer G, Penack O, Rieger C, Rickerts V, Ritter J, Schmidt-Hieber M, Schuelper N, Schwartz S, Ullmann A, Vehreschild JJ, von Lilienfeld-Toal M, Weber T, Wolf HH. Mycoses. 2018 Nov;61(11):796-813. doi: 10.1111/myc.12838. Epub 2018 Sep 3. PMID: 30098069 Review.

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  • EAACI Allergen Immunotherapy Guidelines Group.: EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy.

    Pajno GB, Fernandez-Rivas M, Arasi S, Roberts G, Akdis CA, Alvaro-Lozano M, Beyer K, Bindslev-Jensen C, Burks W, Ebisawa M, Eigenmann P, Knol E, Nadeau KC, Poulsen LK, van Ree R, Santos AF, du Toit G, Dhami S, Nurmatov U, Boloh Y, Makela M, O’Mahony L, Papadopoulos N, Sackesen C, Agache I, Angier E, Halken S, Jutel M, Lau S, Pfaar O, Ryan D, Sturm G, Varga EM, van Wijk RG, Sheikh A, Muraro A Allergy. 2018 Apr;73(4):799-815. doi: 10.1111/all.13319. Epub 2017 Dec 5.

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  • EAACI guidelines on allergen immunotherapy: Executive Statement.

    Muraro A, Roberts G, Halken S, Agache I, Angier E, Fernandez-Rivas M, Gerth van Wijk R, Jutel M, Lau S, Pajno G, Pfaar O, Ryan D, Sturm GJ, van Ree R, Varga EM, Bachert C, Calderon M, Canonica GW, Durham SR, Malling HJ, Wahn U, Sheikh A. Allergy. 2018 Apr;73(4):739-743. doi: 10.1111/all.13420. No abstract available.

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  • Allergy and atopy from infancy to adulthood: Messages from the German birth cohort MAS.

    Lau S, Matricardi PM, Wahn U, Lee YA, Keil T. Ann Allergy Asthma Immunol. 2018 May 25. pii: S1081-1206(18)30378-8. doi: 10.1016/j.anai.2018.05.012. [Epub ahead of print] Review.

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  • Evaluation of food allergy candidate loci in the Genetics of Food Allergy study.

    Marenholz I, Grosche S, Rüschendorf F, Kalb B, Blumchen K, Schlags R, Harandi N, Price M, Hansen G, Seidenberg J, Yürek S, Homuth G, Schmidt CO, Nöthen MM, Hubner N, Niggemann B, Beyer K, Lee YA.: J Allergy Clin Immunol. 2018 Jun 30. pii: S0091-6749(18)30929-1. doi: 10.1016/j.jaci.2018.06.019. [Epub ahead of print] No abstract available.

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  • Hen’s egg allergen in house and bed dust is significantly increased after hen’s egg consumption-A pilot study.

    Trendelenburg V, Tschirner S, Niggemann B, Beyer K.: Allergy. 2018 Jan;73(1):261-264. doi: 10.1111/all.13303. Epub 2017 Sep 26.

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  • Acute Graft Dysfunction 17 Years After Liver Transplant: A Challenging Clinical and Histologic Manifestation of Hepatitis E.

    Hillebrandt KH, Arsenic R, Hofmann J, Eurich D, Gül S, Strücker B, Sauer IM, Pratschke J, Stockmann M, Raschzok N. Exp Clin Transplant. 2018 Jun;16(3):348-351.

  • Cell-Associated Simian Immunodeficiency Virus Accelerates Initial Virus Spread and CD4+ T-Cell Depletion in the Intestinal Mucosa.

    Allers K, Kunkel D, Hofmann J, Stahl-Hennig C, Moos V, Schneider T. J Infect Dis. 2018 Apr, 11;217(9):1421-1425.

  • Prevalence and Clinical Correlates of Chronic Hepatitis E Infection in German Renal Transplant Recipients With Elevated Liver Enzymes.

    Choi M, Hofmann J, Köhler A, Wang B, Bock CT, Schott E, Reinke P, Nickel P. Transplant Direct. 2018 Feb 2;4(2):e341.

  • Advanced Kaposi’s sarcoma in a 2-year-old child.

    Feiterna-Sperling C, Anagnostopoulos I, Hofmann J, Krüger R. Lancet Infect Dis. 2018 Mar;18(3):356.

  • Comprehensive Molecular Approach for Characterization of Hepatitis E Virus Genotype 3 Variants.

    Wang B, Harms D, Papp CP, Niendorf S, Jacobsen S, Lütgehetmann M, Pischke S, Wedermeyer H, Hofmann J, Bock CT. J Clin Microbiol. 2018, Apr 25;56(5). pii: e01686-17.

  • Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells.

    Hammer Q, Rückert T, Borst EM, Dunst J, Haubner A, Durek P, Heinrich F, Gasparoni G, Babic M, Tomic A, Pietra G, Nienen M, Blau IW, Hofmann J, Na IK, Prinz I, Koenecke C, Hemmati P, Babel N, Arnold R, Walter J, Thurley K, Mashreghi MF, Messerle M, Romagnani C. Nat Immunol. 2018 May;19(5):453-463.

  • M. Proteinuria and the Clinical Course of Dobrava-Belgrade Hantavirus Infection.

    Meier M, Kramer J, Jabs WJ, Nolte C, Hofmann J, Krüger DH, Lehnert H, Nitschke Nephron Extra. 2018 Feb 9;8(1):1-10.

  • Accuracy of diagnostic tests and a new algorithm for diagnosing cytomegalovirus colitis in inflammatory bowel diseases: a diagnostic study.

    Kredel LI, Mundt P, van Riesen L, Jöhrens K, Hofmann J, Loddenkemper C, Siegmund B, Preiß JC. Int J Colorectal Dis. 2018 Oct 1.

  • PD-L1/PD-L2 Upregulation: An Imperfect Viral Immune Evasion Mechanism.

    Raftery MJ, Abdelaziz MO, Hofmann J, Schönrich G. Hantavirus-Driven Front Immunol. 2018 Dec 3;9:2560.

  • Severe GABAA receptor encephalitis without seizures: A paediatric case successfully treated with early immunomodulation.

    Nikolaus M, Knierim E, Meisel C, Kreye J, Prüss H, Schnabel D, Kallinich T. Eur J Paediatr Neurol. 2018 May;22(3):558-562. doi: 10.1016/j.ejpn.2018.01.002. Epub 2018 Jan 9.

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  • Myositis-specific antibodies associated with juvenile dermatomyositis.

    Eising K, Peitz J, Unterwalder N, Meisel C, Horneff G. Z Rheumatol. 2018 Feb 6. doi: 10.1007/s00393-017-0415-0. [Epub ahead of print] German.

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  • Tips and tricks in court-Practical experience from a medical viewpoint.

    Burmester GR. Z Rheumatol. 2018 Sep;77(7):587-592. doi: 10.1007/s00393-018-0490-x. Review. German.

    zur Publikation
  • Observational study and brief analysis of diagnostic criteria in relapsing polychondritis.

    Rose T, Schneider U, Bertolo M, Klotsche J, Casteleyn V, Biesen R, Burmester GR, Hiepe F. Rheumatol Int. 2018 Aug 6. doi: 10.1007/s00296-018-4121-2. [Epub ahead of print]

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  • Biomarkers and imaging for diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the BMBF consortium ArthroMark.

    Häupl T, Skapenko A, Hoppe B, Skriner K, Burkhardt H, Poddubnyy D, Ohrndorf S, Sewerin P, Mansmann U, Stuhlmüller B, Schulze-Koops H, Burmester GR. Z Rheumatol. 2018 May;77(Suppl 1):16-23. doi: 10.1007/s00393-018-0458-x. Review. German

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  • Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis.

    Weigold F, Günther J, Pfeiffenberger M, Cabral-Marques O, Siegert E, Dragun D, Philippe A, Regensburger AK, Recke A, Yu X, Petersen F, Catar R, Biesen R, Hiepe F, Burmester GR, Heidecke H, Riemekasten G. Arthritis Res Ther. 2018 Mar 22;20(1):52. doi: 10.1186/s13075-018-1545-8.

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  • Rheumatoid Arthritis. Nat Rev Dis Primers.

    Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, Kavanaugh A, McInnes IB, Solomon DH, Strand V, Yamamoto K. 2018 Feb 8;4:18001. doi: 10.1038/nrdp.2018.1. Review.

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  • Scabies, Periorbital Cellulitis and Recurrent Skin Abscesses due to Panton-Valentine Leukocidin-Positive Staphylococcus aureus Mimic Hyper IgE Syndrome in an Infant.

    Krüger R, Hanitsch LG, Leistner R, Schneider-Burrus S, Hoppe PA, Steinberg S, Hauck F, von Bernuth H. Pediatr Infect Dis J. 2017 Dec;36(12):e347-e348. doi: 10.1097/INF.0000000000001788.

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  • Serum Free Light Chains in CVID-a Marker for Differential Diagnosis.

    Hanitsch LG, Sotzny F, Volk HD, Scheibenbogen C, Wittke K. J Clin Immunol. 2018 Feb;38(2):163-165. doi: 10.1007/s10875-018-0478-y. Epub 2018 Jan 20. No abstract available.

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  • Immunomodulatory treatment with systemic GM-CSF augments pulmonary immune responses and improves neurological outcome after experimental stroke.

    Dames C, Winek K, Beckers Y, Engel O, Meisel A, Meisel C. J Neuroimmunol. 2018 Aug 15;321:144-149. doi: 10.1016/j.jneuroim.2018.03.005. Epub 2018 Mar 9.

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  • Development and validation of a TTR-specific copy number screening tool, and application to potentially relevant patient cohorts.

    Jahic A., Bock A., Duca F., Bonderman D., Mascherbauer J., Windhager R., Auer-Grumbach M. & Beetz C. Mol Cell Probe. 2018;41:61-63.

  • A nonstop variant in REEP1 causes peripheral neuropathy by unmasking a 3’UTR-encoded, aggregation-inducing motif.

    Bock A.S., Günther S., Mohr J., Goldberg L.V., Jahic A., Klisch C., Hübner C.A., Biskup S. & Beetz C. Hum Mutat. 2018;39(2):193-196.

  • T-cell repertoires in refractory coeliac disease.

    Ritter J., Zimmermann K., Jöhrens K., Mende S., Seegebarth A., Siegmund B., Hennig S., Todorova K., Rosenwald A., Daum S., Hummel M. & Schumann M. Gut. 2018;67(4):644-653.

  • Architectural B-cell organization in skeletal muscle identifies subtypes of dermatomyositis.

    Radke J., Koll R., Preuße C., Pehl D., Todorova K., Schönemann C., Allenbach Y., Aronica E., de Visser M., Heppner F.L., Weis J., Doostkam S., Maisonobe T., Benveniste O., Goebel H.H. & Stenzel W. Neurol Neuroimmunol Neuroinflamm. 2018;5(3):e451.

  • The effect of blood sampling and preanalytical processing on human N-glycome.

    Dědová T., Grunow D., Kappert K., Flach D., Tauber R. & Blanchard V. PLoS ONE. 2018;13(7):e0200507

  • The cytoskeleton in ‚couch potato-ism‘: Insights from a murine model of impaired actin dynamics.

    Gertz K., Uhlemann R., Foryst-Ludwig A., Barrientos R.M., Kappert K., Thöne-Reineke C., Djoufack P., Kirschbaum C., Fink K.B., Heinz A., Kintscher U., Endres M. & Kronenberg G. Exp Neurol. 2018;306:34-44.

  • QCM-D surpassing clinical standard for the dose administration of new oral anticoagulant in the patient of coagulation disorders.

    Hussain M., Wendel H.P., Schmidt K., Langer E., Körber M.K., Faul O., Northoff H., von Heymann C. & Gehring F.K. Biosens Bioelectron. 2018;104:15-20.

  • Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and corre-lation with inflammatory activity.

    Schwedler C., Häupl T., Kalus U., Blanchard V., Burmester G.R., Poddubnyy D. & Hoppe B. Arthritis Res Ther. 2018;20(1):44.

  • Nilotinib.

    Gresse M, Kim TD, le Coutre P. Recent Results Cancer Res. 2018;212:69-85. doi: 10.1007/978-3-319-91439-8_3. PMID: 30069625

    zur Publikation
  • Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD.

    Schlenk RF, Weber D, Fiedler W, Salih HR, Wulf G, Salwender H, Schroeder T, Kindler T, Lübbert M, Wolf D, Westermann J, Kraemer D, Götze KS, Horst HA, Krauter J, Girschikofsky M, Ringhoffer M, Südhoff T, Held G, Derigs HG, Schroers R, Greil R, Grießhammer M, Lange E, Burchardt A, Martens U, Hertenstein B, Marretta L, Heuser M, Thol F, Gaidzik VI, Herr W, Krzykalla J, Benner A, Döhner K, Ganser A, Paschka P, Döhner H; German-Austrian AML Study Group. Blood. 2019 Feb 21;133(8):840-851. doi: 10.1182/blood-2018-08-869453. Epub 2018 Dec 18. PMID: 30563875 Clinical Trial.

    zur Publikation
  • Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.

    Thol F, Gabdoulline R, Liebich A, Klement P, Schiller J, Kandziora C, Hambach L, Stadler M, Koenecke C, Flintrop M, Pankratz M, Wichmann M, Neziri B, Büttner K, Heida B, Klesse S, Chaturvedi A, Kloos A, Göhring G, Schlegelberger B, Gaidzik VI, Bullinger L, Fiedler W, Heim A, Hamwi I, Eder M, Krauter J, Schlenk RF, Paschka P, Döhner K, Döhner H, Ganser A, Heuser M. Blood. 2018 Oct 18;132(16):1703-1713. doi: 10.1182/blood-2018-02-829911. Epub 2018 Sep 6. PMID: 30190321 Free PMC article.

    zur Publikation
  • Circular RNAs in Cancer.

    Lux S, Bullinger L. Adv Exp Med Biol. 2018;1087:215-230. doi: 10.1007/978-981-13-1426-1_17. PMID: 30259369 Review.

    zur Publikation
  • Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.

    Döhner H, Dolnik A, Tang L, Seymour JF, Minden MD, Stone RM, Del Castillo TB, Al-Ali HK, Santini V, Vyas P, Beach CL, MacBeth KJ, Skikne BS, Songer S, Tu N, Bullinger L, Dombret H. Leukemia. 2018 Dec;32(12):2546-2557. doi: 10.1038/s41375-018-0257-z. Epub 2018 Oct 1. PMID: 30275526 Free PMC article.

    zur Publikation
  • Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.

    Kabrani E, Chu VT, Tasouri E, Sommermann T, Baßler K, Ulas T, Zenz T, Bullinger L, Schultze JL, Rajewsky K, Sander S. Blood. 2018 Dec 20;132(25):2670-2683. doi: 10.1182/blood-2018-06-856203. Epub 2018 Oct 17. PMID: 30333121

    zur Publikation
  • Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation.

    Jacquelin S, Straube J, Cooper L, Vu T, Song A, Bywater M, Baxter E, Heidecker M, Wackrow B, Porter A, Ling V, Green J, Austin R, Kazakoff S, Waddell N, Hesson LB, Pimanda JE, Stegelmann F, Bullinger L, Döhner K, Rampal RK, Heckl D, Hill GR, Lane SW. Blood. 2018 Dec 27;132(26):2707-2721. doi: 10.1182/blood-2018-04-846220. Epub 2018 Oct 26. PMID: 30366920 Free article.

    zur Publikation
  • Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation.

    Frick M, Chan W, Arends CM, Hablesreiter R, Halik A, Heuser M, Michonneau D, Blau O, Hoyer K, Christen F, Galan-Sousa J, Noerenberg D, Wais V, Stadler M, Yoshida K, Schetelig J, Schuler E, Thol F, Clappier E, Christopeit M, Ayuk F, Bornhäuser M, Blau IW, Ogawa S, Zemojtel T, Gerbitz A, Wagner EM, Spriewald BM, Schrezenmeier H, Kuchenbauer F, Kobbe G, Wiesneth M, Koldehoff M, Socié G, Kroeger N, Bullinger L, Thiede C, Damm F. J Clin Oncol. 2019 Feb 10;37(5):375-385. doi: 10.1200/JCO.2018.79.2184. Epub 2018 Nov 7. PMID: 30403573

    zur Publikation
  • Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.

    Simonetti G, Padella A, do Valle IF, Fontana MC, Fonzi E, Bruno S, Baldazzi C, Guadagnuolo V, Manfrini M, Ferrari A, Paolini S, Papayannidis C, Marconi G, Franchini E, Zuffa E, Laginestra MA, Zanotti F, Astolfi A, Iacobucci I, Bernardi S, Sazzini M, Ficarra E, Hernandez JM, Vandenberghe P, Cools J, Bullinger L, Ottaviani E, Testoni N, Cavo M, Haferlach T, Castellani G, Remondini D, Martinelli G. Cancer. 2019 Mar 1;125(5):712-725. doi: 10.1002/cncr.31837. Epub 2018 Nov 27. PMID: 30480765 Free PMC article.

    zur Publikation
  • Natural tolerance development in cow’s milk allergic children: IgE and IgG4 epitope binding.

    Caubet JC, Lin J, Ahrens B, Gimenez G, Bardina L, Niggemann B, Sampson HA, Beyer K. 2017 Nov;72(11):1677-1685. doi: 10.1111/all.13167. Epub 2017 Jun 9.

    zur Publikation
  • Randomized placebo-controlled trial of hen’s egg consumption for primary prevention in infants.

    Bellach J, Schwarz V, Ahrens B, Trendelenburg V, Aksünger Ö, Kalb B, Niggemann B, Keil T, Beyer K. J Allgergy Clin Immunol. 2017 May;139(5):1591-1599.e2. doi: 10.1016/j.jaci.2016.06.045. Epub 2016 Aug 12.

    zur Publikation
  • Ana o 3-specific IgE is a good predictor for clinically relevant cashew allergy in children.

    Lange L, Lasota L, Finger A, Vlajnic D, Büsing S, Meister J, Broekaert I, Pfannenstiel C, Friedrichs F, Price M, Trendelenburg V, Niggemann B, Beyer K. Allergy. 2017 Apr;72(4):598-603. doi: 10.1111/all.13050. Epub 2016 Nov 17.

    zur Publikation
  • A new framework for the documentation and interpretation of oral food challenges in population-based and clinical Research.

    Grabenhenrich LB, Reich A, Bellach J, Trendelenburg V, Sprikkelman AB, Roberts G, Grimshaw KE, Sigurdardottir S, Kowalski ML, Papadopoulos NG, Quirce S, Dubakiene R, Niggemann B, Fernández-Rivas M, Ballmer-Weber B, van Ree R, Schnadt S, Mills EN, Keil T, Beyer K. Allergy. 2017 Mar;72(3):453-461. doi: 10.1111/all.13049. Epub 2016 Oct 11.

    zur Publikation
  • Severe anaphylaxis requiring intensive care during oral food challenge-It is not always Peanuts.

    Niggemann B, Yürek S, Beyer K. Pediatr Allergy Immunol. 2017 Mar;28(2):201-203. doi: 10.1111/pai.12676. Epub 2016 Dec 20. No abstract available.

    zur Publikation
  • Vaccination and allergy: EAACI position paper, practical aspects.

    Nilsson L, Brockow K, Alm J, Cardona V, Caubet JC, Gomes E, Jenmalm MC, Lau S, Netterlid E, Schwarze J, Sheikh A, Storsaeter J, Skevaki C, Terreehorst I, Zanoni G. Pediatr Allergy Immunol. 2017 Nov;28(7):628-640. doi: 10.1111/pai.12762. Epub 2017 Oct 10. Review.

    zur Publikation
  • Growth curves of „normal“ serum total IgE levels throughout childhood: A quantile analysis in a birth cohort.

    Sacco C, Perna S, Vicari D, Alfò M, Bauer CP, Hoffman U, Forster J, Zepp F, Schuster A, Wahn U, Keil T, Lau S, Matricardi PM. Pediatr Allergy Immunol. 2017 Sep;28(6):525-534. doi: 10.1111/pai.12738.

    zur Publikation
  • Distribution and Activation of CD8+ T Cells in the Duodenal Mucosa before and after HIV Seroconversion.

    Allers K, Puyskens A, Epple HJ, Schürmann D, Hofmann J, Moos V, Schneider T. J Immunol. 2017 Jan 1;198(1):481-491. PubMed PMID: 27872210.

  • Seroprevalence of Cytomegalovirus Infection Among a Rural Population of Côte d’Ivoire.

    Anoh AE, Mossoun A, Akoua-Koffi C, Couacy-Hymann E, Pauly M, Leendertz SA, Kouakou N’goran E, Schubert G, Weiss S, Hofmann J, Leendertz FH, Ehlers B. Viral Immunol. 2017 Jan/Feb;30(1):54-57. PubMed PMID: 28055519.

  • European Multicenter Study on Analytical Performance of DxN Veris System HCV Assay.

    Braun P, Delgado R, Drago M, Fanti D, Fleury H, Gismondo MR, Hofmann J, Izopet J, Kühn S, Lombardi A, Marcos MA, Sauné K, O’Shea S, Pérez-Rivilla A, Ramble J, Trimoulet P, Vila J, Whittaker D, Artus A, Rhodes DW. J Clin Microbiol. 2017 Apr;55(4):1186-1192. PubMed PMID: 28151405; PubMed Central PMCID: PMC5377846.

  • Steep rise in norovirus cases and emergence of a new recombinant strain GII.P16-GII.2, Germany, winter 2016.

    Niendorf S, Jacobsen S, Faber M, Eis-Hübinger AM, Hofmann J, Zimmermann O, Höhne M, Bock CT. Euro Surveill. 2017 Jan 26;22(4). PubMed PMID: 28181902; PubMed Central PMCID: PMC5388089.

  • A European multicentre study on the comparison of HCV viral loads between VERIS HCV assay and COBAS(®) TaqMan(®) HCV Test and RealTime HCV Assay.

    Braun P, Drago M, Fanti D, Fleury H, Hofmann J, Izopet J, Kühn S, Lombardi A, Micheli V, Sauné K, Trimoulet P, Whittaker D, Artus A, Rhodes D. J Clin Virol. 2017 May;90:18-25. PubMed PMID:28319847.

  • Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis.

    Gieß RM, Pfuhl C, Behrens JR, Rasche L, Freitag E, Khalighy N, Otto C, Wuerfel J, Brandt AU, Hofmann J, Eberspächer B, Bellmann-Strobl J, Paul F, Ruprecht K. PLoS One. 2017 Apr 7;12(4):e0175279. PubMed PMID: 28388676; PubMed Central PMCID: PMC5384756.

  • European Multicenter Study on Analytical Performance of Veris HIV-1 Assay.

    Braun P, Delgado R, Drago M, Fanti D, Fleury H, Hofmann J, Izopet J, Kalus U, Lombardi A, Marcos MA, Mileto D, Sauné K, O’Shea S, Pérez-Rivilla A, Ramble J, Trimoulet P, Vila J, Whittaker D, Artus A, Rhodes DW. J Clin Microbiol. 2017 Jul;55(7):2055-2063. PubMed PMID:28424254; PubMed Central PMCID: PMC5483907.

  • Prevalence of human papillomavirus infection of the anal canal in women: A prospective analysis of high-risk populations.

    Kost BP, Hofmann J, Stoellnberger S, Bergauer F, Blankenstein T, Alba-Alejandre I, Stein A, Stuckart C, Weizsäcker K, Mylonas I, Mahner S, Gingelmaier A. Oncol Lett. 2017 Apr;13(4):2495-2501. PubMed PMID:28454426; PubMed Central PMCID: PMC5403543.

  • Identification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland.

    Wang B, Harms D, Hofmann J, Ciardo D, Kneubühl A, Bock CT. Genome Announc. 2017 May 18;5(20). PubMed PMID:28522709; PubMed Central PMCID: PMC5442380.

  • A European multicientre study on the comparison of HIV-1 viral loads between VERIS HIV-1 Assay and Roche COBAS® TAQMAN® HIV-1 test, Abbott RealTime HIV-1 Assay, and Siemens VERSANT HIV-1 Assay.

    Braun P, Delgado R, Drago M, Fanti D, Fleury H, Hofmann J, Izopet J, Kühn S, Lombardi A, Mancon A, Marcos MA, Mileto D, Sauné K, O’Shea S, Pérez-Rivilla A, Ramble J, Trimoulet P, Vila J, Whittaker D, Artus A, Rhodes D. J Clin Virol. 2017 Jul;92:75-82. PubMed PMID: 28599228.

  • Intrauterine therapy of cytomegalovirus infection with valganciclovir: review of the literature.

    Seidel V, Feiterna-Sperling C, Siedentopf JP, Hofmann J, Henrich W, Bührer C, Weizsäcker K. Med Microbiol Immunol. 2017 Oct;206(5):347-354. Review.PubMed PMID: 28733760.

  • Life-threatening systemic rotavirus infection after vaccination in severe combined immunodeficiency (SCID).

    Rosenfeld L, Mas Marques A, Niendorf S, Hofmann J, Gratopp A, Kühl JS, Schulte JH, von Bernuth H, Voigt S. Pediatr Allergy Immunol. 2017 Dec;28(8):841-843. PubMed PMID: 28815852.

  • Transplanting HCV-Infected Kidneys into Uninfected Recipients.

    Halleck F, Budde K, Duerr M, Staeck O, Hofmann J, Eisenberger U, Herzer K,Sterneck M, Gottlieb J, Schulz U. N Engl J Med. 2017 Sep 14;377(11):1103-4. PubMed PMID: 28902583.

  • High maternal expression of SIGLEC1 on monocytes as a surrogate marker of a type I interferon signature is a risk factor for the development of autoimmune congenital heart block.

    Lisney AR, Szelinski F, Reiter K, Burmester GR, Rose T, Dörner T. Ann Rheum Dis. 2017 Aug;76(8):1476-1480. doi: 10.1136/annrheumdis-2016-210927. Epub 2017 May 13.

    zur Publikation
  • Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic Options.

    Strauß R, Rose T, Flint SM, Klotsche J, Häupl T, Peck-Radosavljevic M, Yoshida T, Kyogoku C, Flechsig A, Becker AM, Dao KH, Radbruch A, Burmester GR, Lyons PA, Davis LS, Hiepe F, Grützkau A, Biesen R. J Mol Med (Berl). 2017 Jul;95(7):753-765. doi: 10.1007/s00109-017-1515-7. Epub 2017 Mar 29.

    zur Publikation
  • What is the clinical significance of anti-Sm antibodies in systemic lupus erythematosus? A comparison with anti-dsDNA antibodies and C3.

    Flechsig A, Rose T, Barkhudarova F, Strauss R, Klotsche J, Dähnrich C, Schlumberger W, Enghard P, Burmester GR, Hiepe F, Biesen R. Clin Exp Rheumatol. 2017 Jul-Aug;35(4):598-606. Epub 2017 Mar 3.

    zur Publikation
  • Mapping urinary chemokines in human lupus nephritis: Potentially redundant pathways recruit CD4+ and CD8+ T cells and macrophages.

    Klocke J, Kopetschke K, Grießbach AS, Langhans V, Humrich JY, Biesen R, Dragun D, Radbruch A, Burmester GR, Riemekasten G, Enghard P. Eur J Immunol. 2017 Jan;47(1):180-192. doi: 10.1002/eji.201646387. Epub 2016 Nov 21.

    zur Publikation
  • Automated evaluation of ANA under real-life conditions.

    Loock CD, Egerer K, Feist E, Burmester GR. RMD Open. 2017 Apr 24;3(1):e000409. doi: 10.1136/rmdopen-2016-000409. eCollection 2017.

    zur Publikation
  • Novel treatment strategies in rheumatoid Arthritis.

    Burmester GR, Pope JE. Lancet. 2017 Jun 10;389(10086):2338-2348. doi: 10.1016/S0140-6736(17)31491-5. Review.

    zur Publikation
  • The Diagnosis and Treatment of Sjögren’s Syndrome.

    Stefanski AL, Tomiak C, Pleyer U, Dietrich T, Burmester GR, Dörner T. Dtsch Arztebl Int. 2017 May 26;114(20):354-361. doi: 10.3238/arztebl.2017.0354.

    zur Publikation
  • Are interferon-related biomarkers advantageous for monitoring disease activity in systemic lupus erythematosus? A longitudinal benchmark study.

    Rose T, Grützkau A, Klotsche J, Enghard P, Flechsig A, Keller J, Riemekasten G, Radbruch A, Burmester GR, Dörner T, Hiepe F, Biesen R. Rheumatology (Oxford). 2017 Sep 1;56(9):1618-1626. doi: 10.1093/rheumatology/kex220.

    zur Publikation
  • Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers.

    Pfortmueller CA, Meisel C, Fux M, Schefold JC. Intensive Care Med Exp. 2017 Oct 23;5(1):49. doi: 10.1186/s40635-017-0163-0. Review.

    zur Publikation
  • Antibiotic Prophylaxis, Immunoglobulin Substitution and Supportive Measures Prevent Infections in MECP2 Duplication Syndrome.

    Bauer M, Krüger R, Kölsch U, Unterwalder N, Meisel C, Wahn V, von Bernuth H. Pediatr Infect Dis J. 2018 May;37(5):466-468. doi: 10.1097/INF.0000000000001799.

    zur Publikation
  • Interpreting Immune Mediator Dysbalance in Sepsis.

    Pfortmueller CA, Meisel C, Schefold JC. Crit Care Med. 2017 Oct;45(10):e1094-e1095. doi: 10.1097/CCM.0000000000002547. No abstract available.

    zur Publikation
  • The Randomized Controlled STRAWINSKI Trial: Procalcitonin-Guided Antibiotic Therapy after Stroke.

    Ulm L, Hoffmann S, Nabavi D, Hermans M, Mackert BM, Hamilton F, Schmehl I, Jungehuelsing GJ, Montaner J, Bustamante A, Katan M, Hartmann A, Ebmeyer S, Dinter C, Wiemer JC, Hertel S, Meisel C, Anker SD, Meisel A. Front Neurol. 2017 Apr 24;8:153. doi: 10.3389/fneur.2017.00153. eCollection 2017.

    zur Publikation
  • Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia – The PREDICT study.

    Hoffmann S, Harms H, Ulm L, Nabavi DG, Mackert BM, Schmehl I, Jungehulsing GJ, Montaner J, Bustamante A, Hermans M, Hamilton F, Göhler J, Malzahn U, Malsch C, Heuschmann PU, Meisel C, Meisel A; PREDICT Investigators. J Cereb Blood Flow Metab. 2017 Dec;37(12):3671-3682. doi: 10.1177/0271678X16671964. Epub 2016 Oct 14.

    zur Publikation
  • Influenza Vaccination in Patients with Common Variable Immunodeficiency (CVID).

    Mieves JF, Wittke K, Freitag H, Volk HD, Scheibenbogen C, Hanitsch LG. Curr Allergy Asthma Rep. 2017 Oct 5;17(11):78. doi: 10.1007/s11882-017-0749-3. Review.

    zur Publikation
  • IgG subclass deficiencies in children: Facts and fiction.

    Wahn V, von Bernuth H. Pediatr Allergy Immunol. 2017 Sep;28(6):521-524. doi: 10.1111/pai.12757. Epub 2017 Aug 7. Review.

    zur Publikation
  • Life-threatening systemic rotavirus infection after vaccination in severe combined immunodeficiency (SCID).

    Rosenfeld L, Mas Marques A, Niendorf S, Hofmann J, Gratopp A, Kühl JS, Schulte JH, von Bernuth H, Voigt S. Pediatr Allergy Immunol. 2017 Dec;28(8):841-843. doi: 10.1111/pai.12771. Epub 2017 Oct 9. No abstract available.

    zur Publikation
  • Doublet-Mediated DNA Rearrangement-A Novel and Potentially Underestimated Mecha-nism for the Formation of Recurrent Pathogenic Deletions.

    Jahic A., Hinreiner S., Emberger W., Hehr U., Zuchner S. & Beetz C. Hum Mutat. 2017;38(3):275-278.

  • Werner Reutter: A Visionary Pioneer in Molecular Glycobiology.

    Hinderlich S., Tauber R., Bertozzi C.R. & Hackenberger C.P.R. Chembiochem. 2017;18(13):1141-1145.

  • The Cell-Surface N-Glycome of Human Embryonic Stem Cells and Differentiated Hepatic Cells thereof.

    Montacir H., Freyer N., Knöspel F., Urbaniak T., Dedova T., Berger M., Damm G., Tauber R., Zeilinger K. & Blanchard V. Chembiochem. 2017;18(13):1234-1241.

  • The ascites N-glycome of epithelial ovarian cancer patients.

    Biskup K., Braicu E.I., Sehouli J., Tauber R. & Blanchard V. J Proteomics. 2017;157:33-39.

  • Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 Å Resolution.

    Wedepohl S., Dernedde J., Vahedi-Faridi A., Tauber R., Saenger W. & Bulut H. Chembiochem. 2017;18(13):1338-1345.

  • Placental expression of sFlt-1 and PlGF in early preeclampsia vs. early IUGR vs. age-matched healthy pregnancies.

    Hoeller A., Ehrlich L., Golic M., Herse F., Perschel F.H., Siwetz M., Henrich W., Dechend R., Huppertz B. & Verlohren S. Hypertens Pregnancy. 2017;36(2):151-160.

  • PCSK9 regulates the chemokine receptor CCR2 on monocytes.

    Grune J., Meyborg H., Bezhaeva T., Kappert K., Hillmeister P., Kintscher U., Pieske B. & Stawowy P. Biochem Bioph Res Co. 2017;485(2):312-318.

  • Increased placental sFlt-1 but unchanged PlGF expression in late-onset preeclampsia.

    Ehrlich L., Hoeller A., Golic M., Herse F., Perschel F.H., Henrich W., Dechend R., Hup-pertz B. & Verlohren S. Hypertens Pregnancy. 2017;36(2):175-185.

  • In vitro and ex vivo Measurement of Prophylactic Dabigatran Concentrations with a New Ecarin-Based Thromboelastometry Test.

    Körber M.K., Langer E., Köhr M., Wernecke K.D., Korte W. & von Heymann C. Transfus Med Hemoth. 2017;44(2):100-105.

  • High incidence of cardiac dysfunction and response to antiviral treatment in patients with chronic hepatitis C virus infection.

    Poller W., Kaya Z., Muche M., Kasner M., Skurk C., Kappert K., Tauber R., Escher F., Schul-theiss H.P., Epple H.J. & Landmesser U. Clin Res Cardiol. 2017;106(7):551-556.

  • Diagnostic performance of a high-sensitive troponin T assay and a troponin T point of care assay in the clinical routine of an Emergency Department: A clinical cohort study.

    Slagman A., von Recum J., Möckel M., Holert F., Meyer zum Büschenfelde D., Müller C. & Searle J. Int J Cardiol. 2017; 230:454-460.

  • Diagnosis of preeclampsia and fetal growth restriction with the sFlt-1/PlGF ratio: Diag-nostic accuracy of the automated immunoassay Kryptor®.

    Dröge L.A., Höller A., Ehrlich L., Verlohren S., Henrich W. & Perschel F.H. Pregnancy Hypertens. 2017;8:31-36.

  • AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.

    Krueger F., Kappert K., Foryst-Ludwig A., Kramer F., Clemenz M., Grzesiak A., Sommerfeld M., Paul Frese J., Greiner A., Kintscher U., Unger T. & Kaschina E. Clin Sci. 2017;131(15):1989-2005.

  • Angiogenic Markers and Cardiovascular Indices in the Prediction of Hypertensive Disor-ders of Pregnancy.

    Verlohren S., Perschel F.H., Thilaganathan B., Dröge L.A., Henrich W., Busjahn A. & Khalil A. Hypertension. 2017;69(6):1192-1197.

  • Ana o 3-specific IgE is a good predictor for clinically relevant cashew allergy in children.

    Lange L, Lasota L, Finger A, Vlajnic D, Büsing S, Meister J, Brockaert I, Pfannenstiel C, Friedrichs F, Price M, Trendelenburg V, Niggemann B, Beyer K. Allergy. 2016 Sep 19. doi: 10.1111/all.13050

    zur Publikation
  • Randomized placebo-controlled trial of hen’s egg consumption for primary prevention in infants.

    Bellach J, Schwarz V, Ahrens B, Trendelenburg V, Aksünger Ö, Kalb B, Niggemann B, Keil T, Beyer K. J Allergy Clin Immunol. 2016 Aug 12. pii: S0091-6749(16)30784-9. doi: 10.1016/j.jaci.2016.06.045.

    zur Publikation
  • Food allergy in childhood.

    Beyer K, Niggemann B. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Jun;59(6):732-6. doi: 10.1007/s00103-016-2353-4. German.

    zur Publikation
  • The component-specific to total IgE ratios do not improve peanut and hazelnut allergy diagnoses.

    Grabenhenrich L, Lange L, Härtl M, Kalb B, Ziegert M, Finger A, Harandi N, Schlags R, Gappa M, Puzzo L, Stephan V, Heigele T, Büsing S, Ott H, Niggemann B, Beyer K. J Allergy Clin Immunol. 2016 Jun;137(6):1751-1760.e8. doi: 10.1016/j.jaci.2016.01.043. Epub 2016 Apr 14.

    zur Publikation
  • Wheat protein recognition pattern in tolerant and allergic children.

    Sievers S, Rawel HM, Ringel KP, Niggemann B, Beyer K. Pediatr Allergy Immunol. 2016 Mar;27(2):147-55. doi: 10.1111/pai.12502. Epub 2015 Dec 22

    zur Publikation
  • Time for a new grading system for allergic reactions?

    Niggemann B, Beyer K. Allergy. 2016 Feb;71(2):135-6. doi: 10.1111/all.12765. Epub 2015 Sep 28.

    zur Publikation
  • The effect of timing of antiretroviral therapy on CD4+ T-cell reconstitution in the intestine of HIV-infected patients.

    Allers K, Puyskens A, Epple HJ, Schürmann D, Hofmann J, Moos V, Schneider T. Mucosal Immunol. 2016 Jan;9(1):265-74. PubMed PMID: 26129649.

  • Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation.

    Voigt S, Hofmann J, Edelmann A, Sauerbrei A, Kühl JS. Transpl Infect Dis. 2016 Oct;18(5):791-794. PubMed PMID: 27482652.

  • Moraxella catarrhalis decreases antiviral innate immune responses by down-regulation of TLR3 via inhibition of p53 in human bronchial epithelial cells.

    Heinrich A, Haarmann H, Zahradnik S, Frenzel K, Schreiber F, Klassert TE, Heyl KA, Endres AS, Schmidtke M, Hofmann J, Slevogt H. FASEB J. 2016 Jun;30(6):2426-34. PubMed PMID: 26979086.

  • Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance.

    Fischer L, Imrich E, Sampaio KL, Hofmann J, Jahn G, Hamprecht K, Göhring K. Antiviral Res. 2016 Jul;131:1-8.PubMed PMID: 27058773.

  • Antibody producing B lineage cells invade the central nervous system predominantly at the time of and triggered by acute Epstein-Barr virus infection: A hypothesis on the origin of intrathecal immunoglobulin synthesis in multiple sclerosis.

    Otto C, Hofmann J, Ruprecht K. Med Hypotheses. 2016 Jun;91:109-13. PubMed PMID: 27142157.

  • Two-Year Follow-Up Analysis of Telaprevir-Based Antiviral Triple Therapy for HCV Recurrence in Genotype 1 Infected Liver Graft Recipients as a First Step towards Modern HCV Therapy.

    Klein F, Neuhaus R, Eurich D, Hofmann J, Bayraktar S, Pratschke J, Bahra M. Hepat Res Treat. 2016;2016:8325467. PubMed PMID: 27195149.

  • Thermal Stability of Hepatitis E Virus as Estimated by a Cell Culture Method.

    Johne R, Trojnar E, Filter M, Hofmann J. Appl Environ Microbiol. 2016 Jun 30;82(14):4225-31. PubMed PMID: 27208095.

  • High seroprevalence of antibodies against Kaposi’s sarcoma-associated herpesvirus (KSHV) among HIV-1-infected children and adolescents in a non-endemic population.

    Feiterna-Sperling C, Königs C, Notheis G, Buchholz B, Krüger R, Weizsäcker K, Eberle J, Hanhoff N, Gärtner B, Heider H, Krüger DH, Hofmann J. Med Microbiol Immunol. 2016 Oct;205(5):425-34. PubMed PMID: 27240652.

  • Acute Graft Dysfunction 17 Years After Liver Transplant: A Challenging Clinical and Histologic Manifestation of Hepatitis E.

    Hillebrandt KH, Arsenic R, Hofmann J, Eurich D, Gül S, Strücker B, Sauer IM, Pratschke J, Stockmann M, Raschzok N. Exp Clin Transplant. 2016 Jun 15.PubMed PMID: 27310664.

  • Clinical outcome of norovirus infection in renal transplant patients.

    Brakemeier S, Taxeidi SI, Dürr M, Hofmann J, Schmidt D, Bachmann F, Gaedeke J, Budde K. Clin Transplant. 2016 Oct;30(10):1283-1293. PubMed PMID:27447127.

  • High prevalence of anti-hepatitis E virus antibodies in outpatients with chronic liver disease in a university medical center in Germany.

    Schulz M, Beha D, Plehm K, Zöllner C, Hofmann J, Schott E. Eur J Gastroenterol Hepatol. 2016 Dec;28(12):1431-1436. PubMed PMID: 27552296.

  • Clinical characterization of two severe cases of hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses Puumala and Dobrava-Belgrade genotype Sochi.

    Krautkrämer E, Nusshag C, Baumann A, Schäfer J, Hofmann J, Schnitzler P, Klempa B, Witkowski PT, Krüger DH, Zeier M. BMC Infect Dis. 2016 Nov 14;16(1):675. PubMed PMID: 27842513.

  • Laboratory diagnostics in rheumatology.

    Dörner T, Fleck M. Z Rheumatol. 2016 May;75(4):354-5. doi: 10.1007/s00393-016-0087-1. German. No abstract available.

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  • Effects of treatment with etanercept versus methotrexate on sleep quality, fatigue and selected immune parameters in patients with active rheumatoid Arthritis.

    Detert J, Dziurla R, Hoff P, Gaber T, Klaus P, Bastian H, Braun T, Schellmann S, Penzel T, Fietze I, Loeschmann PA, Jaehnig P, Straub RH, Burmester GR, Buttgereit F. Clin Exp Rheumatol. 2016 Sep-Oct;34(5):848-856. Epub 2016 Jun 22.

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  • Sequential high-content profiling of the IgG-autoantibody repertoire reveals novel antigens in rheumatoid Arthritis.

    Vordenbäumen S, Lueking A, Budde P, Zucht HD, Goehler H, Brinks R, Fischer-Betz R, Richter J, Bleck E, Detert J, Langer HE, Sörgel A, Burmester GR, Schulz-Knappe P, Schneider M. Arthritis Res Ther. 2016 Oct 12;18(1):235.

    zur Publikation
  • SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren’s Syndrome.

    Rose T, Szelinski F, Lisney A, Reiter K, Fleischer SJ, Burmester GR, Radbruch A, Hiepe F, Grützkau A, Biesen R, Dörner T. RMD Open. 2016 Dec 30;2(2):e000292. doi: 10.1136/rmdopen-2016-000292. eCollection 2016.

    zur Publikation
  • Targeting GM-CSF in rheumatoid Arthritis.

    Avci AB, Feist E, Burmester GR. Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):39-44. Epub 2016 Jul 21. Review.

    zur Publikation
  • BCR-ABL-positive acute myeloid leukemia: a new entity? Analysis of clinical and molecular features.

    Neuendorff N R, Burmeister T, Dörken B, Westermann J Annaly of hematology DOI 10.1007/s00277-016-2721-z

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  • Durchflusszytometrische Immunphänotypisierung in der klinischen Diagnostik.

    Ostendorf, B N, Hansmann, L, Ludwig, w-D, Dörken, B, Ratei, R, Westermann, J. Dtsch Med Wochenschr 2016; 141: 1569–1574

    zur Publikation
  • Cellular and humoral influenza-specific immune response upon vaccination in patients with common variable immunodeficiency and unclassified antibody deficiency.

    Hanitsch LG, Löbel M, Mieves JF, Bauer S, Babel N, Schweiger B, Wittke K, Grabowski P, Volk HD, Scheibenbogen C. Vaccine. 2016 May 5;34(21):2417-2423. doi: 10.1016/j.vaccine.2016.03.091. Epub 2016 Apr 5.

    zur Publikation
  • Key findings to expedite the diagnosis of hyper-IgE syndromes in infants and young children.

    Hagl B, Heinz V, Schlesinger A, Spielberger BD, Sawalle-Belohradsky J, Senn-Rauh M, Magg T, Boos AC, Hönig M, Schwarz K, Dückers G, von Bernuth H, Pache C, Karitnig-Weiss C, Belohradsky BH, Frank J, Niehues T, Wahn V, Albert MH, Wollenberg A, Jansson AF, Renner ED. Pediatr Allergy Immunol. 2016 Mar;27(2):177-84. doi: 10.1111/pai.12512. Epub 2016 Jan 26.

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  • Stroke induces specific alteration of T memory compartment controlling auto-reactive CNS antigen-specific T cell responses.

    Klehmet J, Hoffmann S, Walter G, Meisel C, Meisel A. J Neurol Sci. 2016 Sep 15;368:77-83. doi: 10.1016/j.jns.2016.06.039. Epub 2016 Jun 17.

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  • EBNA1 antigen-specific CD8+ T cells in cerebrospinal fluid of patients with multiple sclerosis.

    Erdur H, Scholz V, Streitz M, Hammer M, Meisel C, Schönemann C, Wandinger KP, Rosche B. J Neuroimmunol. 2016 May 15;294:14-7. doi: 10.1016/j.jneuroim.2016.03.010. Epub 2016 Mar 19.

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  • A polymorphic Alu insertion that mediates distinct disease-associated deletions.

    Jahic A., Erichsen A.K., Deufel T., Tallaksen C.M. & Beetz C. Eur J Hum Genet. 2016;24(9):1371-4.

  • Novel Genetic, Clinical, and Pathomechanistic Insights into TFG-Associated Hereditary Spastic Paraplegia.

    Harlalka G.V., McEntagart M.E., Gupta N., Skrzypiec A.E., Mucha M.W., Chioza B.A., Simp-son M.A., Sreekantan-Nair A., Pereira A., Günther S., Jahic A., Modarres H., Moore-Barton H., Trembath R.C., Kabra M., Baple E.L., Thakur S., Patton M.A., Beetz C., Pawlak R. & Crosby A.H. Hum Mutat. 2016;37(11):1157-1161.

  • Maternal mosaicism for IDUA deletion clarifies recurrence risk in MPS I.

    1. Breen C., Mercer J., Jones S.A., Jahic A., Heptinstall L., Tylee K., Newman W.G. & Beetz C. Hum Genome Var. 2016;3:16031.

  • Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identi-fied DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.

    Horie M., Yamaguchi Y., Saito A., Nagase T., Lizio M., Itoh M., Kawaji H., Lassmann T., Car-ninci P., Forrest A.R.R., Hayashizaki Y., Suzutani T., Kappert K., Micke P. & Ohshima M. Sci Rep. 2016;6:33666.

  • Therapeutic Targeting of Telomerase.

    Jäger K. & Walter M. Genes-basel. 2016;7(7)

  • Structural requirements of mono- and multivalent L-selectin blocking aptamers for en-hanced receptor inhibition in vitro and in vivo.

    Riese S.B., Buscher K., Enders S., Kuehne C., Tauber R. & Dernedde J. Nanomed-Nanotechnol. 2016;12(4):901-908.

  • Preemptive Isolation Precautions of Patients at High Risk for Methicillin-Resistant Staphy-lococcus aureus in Combination With Ultrarapid Polymerase Chain Reaction Screening as an Effective Tool for Infection Control.

    Hallak G., Neuner B., Schefold J.C., Gorzelniak K., Rapsch B., Pfüller R., Stengel D., Well-mann J., Ekkernkamp A. & Walter M. Infect Cont Hosp Ep. 2016;37(12):1489-1491.

  • Pioglitazone alleviates cardiac and vascular remodelling and improves survival in mono-crotaline induced pulmonary arterial hypertension.

    Behringer A., Trappiel M., Berghausen E.M., Ten Freyhaus H., Wellnhofer E., Odenthal M., Blaschke F., Er F., Gassanov N., Rosenkranz S., Baldus S., Kappert K. & Caglayan E. N-S Arch Pharmacol. 2016;389(4):369-79.

  • Inhibition of Src homology 2 domain-containing phosphatase 1 increases insulin sensitivi-ty in high-fat diet-induced insulin-resistant mice.

    Krüger J., Wellnhofer E., Meyborg H., Stawowy P., Östman A., Kintscher U. & Kappert K. Febs Open Bio. 2016;6(3):179-89.

  • In vitro reversal of supratherapeutic rivaroxaban levels with coagulation factor concen-trates.

    Körber M.K., Langer E., Kaufner L., Sander M. & Von Heymann C. Blood Transfus. 2016;14(5):481-6.

  • Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis.

    Ohshima M., Yamaguchi Y., Ambe K., Horie M., Saito A., Nagase T., Nakashima K., Ohki H., Kawai T., Abiko Y., Micke P. & Kappert K. J Clin Periodontol. 2016;43(2):128-37.

  • Delta-He, Ret-He and a New Diagnostic Plot for Differential Diagnosis and Therapy Moni-toring of Patients Suffering from Various Disease-Specific Types of Anemia.

    Weimann A., Cremer M., Hernáiz-Driever P. & Zimmermann M. Clin Lab. 2016;62(4):667-77.

  • Acute-phase glycoprotein N-glycome of ovarian cancer patients analyzed by CE-LIF.

    Weiz S., Wieczorek M., Schwedler C., Kaup M., Braicu E.I., Sehouli J., Tauber R. & Blanchard V. Electrophoresis. 2016;37(11):1461-7.

  • Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent Thrombosis.

    Hytönen J., Leppänen O., Braesen J.H., Schunck W.H., Mueller D., Jung F., Mrowietz C., Jastroch M., von Bergwelt-Baildon M., Kappert K., Heuser A., Drenckhahn J.D., Pieske B., Thierfelder L., Ylä-Herttuala S. & Blaschke F. Arterioscl Throm Vas. 2016;36(8):1534-48.

  • Allergen and allergy risk assessment, allergen management, and gaps in the European Food Information Regulation (FIR): Are allergic consumers adequately protected by current statutory food safety and labelling regulations?

    Reese I, Holzhauser T, Schnadt S, Dölle S, Kleine-Tebbe J, Raithel M, Worm M, Zuberbier T, Vieths S. Allergo J Int. 2015;24:180-184. Epub 2015 Sep 28.

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  • Chemokine levels in serum of children with atopic dermatitis with regard to severity and sensitization status.

    Ahrens B, Schulz G, Bellach J, Niggemann B, Beyer K. Pediatr Allergy Immunol. 2015 Nov;26(7):634-40. doi: 10.1111/pai.12431. Epub 2015 Jul 14.

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  • Detection of relevant amounts of cow’s milk protein in non-pre-packed bakery products sold as cow’s milk-free.

    Trendelenburg V, Enzian N, Bellach J, Schnadt S, Niggemann B, Beyer K. Allergy. 2015 May;70(5):591-7. doi: 10.1111/all.12588. Epub 2015 Feb 26.

    zur Publikation
  • Predictive values of component-specific IgE for the outcome of peanut and hazelnut food challenges in children.

    Beyer K, Grabenhenrich L, Härtl M, Beder A, Kalb B, Ziegert M, Finger A, Harandi N, Schlags R, Gappa M, Puzzo L, Röblitz H, Millner-Uhlemann M, Büsing S, Ott H, Lange L, Niggemann B. Allergy. 2015 Jan;70(1):90-8. doi: 10.1111/all.12530. Epub 2014 Nov 30.

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  • Successful Treatment of Chronic Hepatitis E After an Orthotopic Liver Transplant With Ribavirin Monotherapy.

    Klein F, Neuhaus R, Hofmann J, Rudolph B, Neuhaus P, Bahra M. Exp Clin Transplant. 2015 Jun;13(3):283-6. PMID: 24779678.

  • Hantavirus-induced pathogenesis in mice with a humanized immune system.

    Kobak L, Raftery MJ, Voigt S, Kühl AA, Kilic E, Kurth A, Witkowski P, Hofmann J, Nitsche A, Schaade L, Krüger DH, Schönrich G. J Gen Virol. 2015 Jun;96(Pt 6):1258-63. PMID: 25678530.

  • Association of low serum TGF-β level in hantavirus infected patients with severe disease.

    Sadeghi M, Lahdou I, Ettinger J, Navid MH, Daniel V, Zeier M, Hofmann J, Opelz G, Schnitzler P. BMC Immunol. 2015 Apr 14;16:19. PMCID: 4399110.

  • Serum hepatitis B virus RNA levels as an early predictor of hepatitis B envelope antigen seroconversion during treatment with polymerase inhibitors.

    van Bömmel F, Bartens A, Mysickova A, Hofmann J, Krüger DH, Berg T, Edelmann A. Hepatology. 2015 Jan;61(1):66-76. PMID: 25132147.

  • Association of serum Epstein-Barr nuclear antigen-1 antibodies and intrathecal immunoglobulin synthesis in early multiple sclerosis.

    Pfuhl C, Oechtering J, Rasche L, Gieß RM, Behrens JR, Wakonig K, Freitag E, Pache FC, Otto C, Hofmann J, Eberspächer B, Bellmann-Strobl J, Paul F, Ruprecht K. J Neuroimmunol. 2015 Aug 15;285:156-60. PMID: 26198934.

  • Does proficiency testing improve the quality of hantavirus serodiagnostics? Experiences with INSTAND EQA schemes.

    Hofmann J, Grunert HP, Donoso-Mantke O, Zeichhardt H, Kruger DH. Int J Med Microbiol. 2015, Oct;305(7):607-11. PMID: 26342877.

  • Herpes Simplex Virus Sepsis in a Young Woman with Crohn’s Disease.

    Haag LM, Hofmann J, Kredel LI, Holzem C, Kühl AA, Taube ET, Schubert S, Siegmund B, Epple HJ. J Crohns Colitis. 2015 Dec;9(12):1169-73. PMID: 26351382.

  • Rheumatische und muskuloskelettale Erkrankungen–eine wissenschaftliche und klinische Herausforderung.

    Burmester GR. Drug Res (Stuttg). 2015 Nov;65 Suppl 1:S2. doi: 10.1055/s-0035-1558059. Epub 2015 Nov 4. German. No abstract available.

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  • Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.

    von Spee-Mayer C, Siegert E, Abdirama D, Rose A, Klaus A, Alexander T, Enghard P, Sawitzki B, Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Humrich JY. Ann Rheum Dis. 2016 Jul;75(7):1407-15. doi: 10.1136/annrheumdis-2015-207776. Epub 2015 Aug 31.

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  • Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid Arthritis.

    Lindenberg L, Spengler L, Bang H, Dorner T, Maslyanskiy AL, Lapin SV, Ilivanova EI, Martinez-Gamboa L, Bastian H, Wittenborn E, Egerer K, Burmester GR, Feist E. Arthritis Res Ther. 2015 Aug 13;17:206. doi: 10.1186/s13075-015-0717-z.

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  • The cellular signature of urinary immune cells in Lupus nephritis: new insights into potential biomarkers.

    Kopetschke K, Klocke J, Grießbach AS, Humrich JY, Biesen R, Dragun D, Burmester GR, Enghard P, Riemekasten G. Arthritis Res Ther. 2015 Apr 3;17:94. doi: 10.1186/s13075-015-0600-y.

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  • Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE.

    Humrich JY, von Spee-Mayer C, Siegert E, Alexander T, Hiepe F, Radbruch A, Burmester GR, Riemekasten G. Ann Rheum Dis. 2015 Apr;74(4):791-2. doi: 10.1136/annrheumdis-2014-206506. Epub 2015 Jan 21. No abstract available.

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  • Circadian rhythms of cellular immunity in rheumatoid arthritis: a hypothesis-generating study.

    Spies CM, Hoff P, Mazuch J, Gaber T, Maier B, Strehl C, Hahne M, Jakstadt M, Huscher D, Burmester GR, Detert J, Kramer A, Buttgereit F. Clin Exp Rheumatol. 2015 Jan-Feb;33(1):34-43. Epub 2014 Dec 22.

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  • Effects of 60-day bed rest with and without exercise on cellular and humoral immunological Parameters.

    Hoff P, Belavý DL, Huscher D, Lang A, Hahne M, Kuhlmey AK, Maschmeyer P, Armbrecht G, Fitzner R, Perschel FH, Gaber T, Burmester GR, Straub RH, Felsenberg D, Buttgereit F. Cell Mol Immunol. 2015 Jul;12(4):483-92. doi: 10.1038/cmi.2014.106. Epub 2014 Nov 10.

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  • Infectious and Immunologic Phenotype of MECP2 Duplication Syndrome.

    Bauer M, Kölsch U, Krüger R, Unterwalder N, Hameister K, Kaiser FM, Vignoli A, Rossi R, Botella MP, Budisteanu M, Rosello M, Orellana C, Tejada MI, Papuc SM, Patat O, Julia S, Touraine R, Gomes T, Wenner K, Xu X, Afenjar A, Toutain A, Philip N, Jezela-Stanek A, Gortner L, Martinez F, Echenne B, Wahn V, Meisel C, Wieczorek D, El-Chehadeh S, Van Esch H, von Bernuth H. J Clin Immunol. 2015 Feb;35(2):168-81. doi: 10.1007/s10875-015-0129-5. Epub 2015 Feb 27. PMID: 25721700

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  • In patients with defects in Toll-like and Interleukin-1 receptor (TIR)-dependent signalling septic arthritis may present like Juvenile Idiopathic Arthritis.

    Kallinich T, Kölsch U, Lieber M, Unterwalder N, Spors B, Lorenz M, Schwarz K, Meisel C, von Bernuth H. Pediatr Allergy Immunol. 2015 Apr 9. doi: 10.1111/pai.12373. [Epub ahead of print] PMID: 25865658

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  • Late-Onset Disseminated Mycobacterium avium intracellulare Complex Infection (MAC), Cerebral Toxoplasmosis and Salmonella Sepsis in a German Caucasian Patient with Unusual Anti-Interferon-Gamma IgG1 Autoantibodies.

    Hanitsch LG1, Löbel M, Müller-Redetzky H, Schürmann M, Suttorp N, Unterwalder N, Mönnich U, Meisel C, Wittke K, Volk HD, Scheibenbogen C, Kölsch U. J Clin Immunol. 2015 Apr 15. [Epub ahead of print] PMID: 25875701

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  • Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.

    Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G. J Immu-nol. 2015 Sep 15;195(6):2560-70

  • Modeling risk for severe adverse outcomes using angiogenic factor measurements in women with suspected preterm preeclampsia.

    Palomaki G.E., Haddow J.E., Haddow H.R.M., Salahuddin S., Geahchan C., Cerdeira A.S., Verlohren S., Perschel F.H., Horowitz G., Thadhani R., Karumanchi S.A. & Rana S. Prenatal Diag. 2015;35(4):386-93.

  • Effects of 60-day bed rest with and without exercise on cellular and humoral immunological parameters.

    Hoff P., Belavý D.L., Huscher D., Lang A., Hahne M., Kuhlmey A.K., Maschmeyer P., Armbrecht G., Fitzner R., Perschel F.H., Gaber T., Burmester G.R., Straub R.H., Felsenberg D. & Buttgereit F. Cell Mol Immunol. 2015;12(4):483-92.

  • CT-proET1 predicts pulmonary hemodynamics in Scleroderma-associated pulmonary hypertension.

    Ten Freyhaus H., Dumitrescu D., Schnorbach S., Kappert K., Viethen T., Hellmich M., Hunzelmann N. & Rosenkranz S. Clin Res Cardiol. 2015;104(6):525-9.

  • Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice.

    Krüger J., Brachs S., Trappiel M., Kintscher U., Meyborg H., Welln-hofer E., Thöne-Reineke C., Stawowy P., Östman A., Birkenfeld A.L., Böhmer F.D. & Kappert K. Mol Metab. 2015;4(4):325-36.

  • Autoantikörper bei juveniler idiopathischer inflammatorischer Myopathie

    González-González J.B., Meisel C. & Unterwalder N. Arthritis Rheuma. 2015;35(03):176-182.

  • Triggers and treatment of anaphylaxis: an analysis of 4,000 cases from Germany, Austria and Switzerland.

    Worm M1, Eckermann O, Dölle S, Aberer W, Beyer K, Hawranek T, Hompes S, Koehli A, Mahler V, Nemat K, Niggemann B, Pföhler C, Rabe U, Reissig A, Rietschel E, Scherer K, Treudler R, Ruëff F Dtsch Arztebl Int. 2014 May 23;111(21):367-75. doi: 10.3238/arztebl.2014.0367. PMID: 24939374

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  • Modified oral food challenge used with sensitization biomarkers provides more real-life clinical thresholds for peanut allergy.

    Blumchen K, Beder A, Beschorner J, Ahrens F, Gruebl A, Hamelmann E5, Hansen G, Heinzmann A, Nemat K, Niggemann B, Wahn U, Beyer K. J Allergy Clin Immunol. 2014 May 13. pii: S0091-6749(14)00517-X. doi: 10.1016/j.jaci.2014.03.035. PMID: 24831438

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  • EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy.

    Muraro A, Werfel T, Hoffmann-Sommergruber K, Roberts G, Beyer K, Bindslev-Jensen C, Cardona V, Dubois A, duToit G, Eigenmann P, Fernandez Rivas M, Halken S, Hickstein L, Høst A, Knol E, Lack G, Marchisotto MJ, Niggemann B, Nwaru BI, Papadopoulos NG, Poulsen LK, Santos AF, Skypala I, Schoepfer A, Van Ree R, Venter C, Worm M, Vlieg-Boerstra B, Panesar S, de Silva D, Soares-Weiser K, Sheikh A, Ballmer-Weber BK, Nilsson C, de Jong NW, Akdis CA Allergy. 2014 Jun 9. doi: 10.1111/all.12429. PMID: 24909706

    zur Publikation
  • Parental hay fever reinforces IgE to pollen as pre-clinical biomarker of hay fever in childhood.

    Hatzler L1, Panetta V, Illi S, Hofmaier S, Rohrbach A, Hakimeh D, Bauer CP, Hoffman U, Forster J, Zepp F, Schuster A, Stock P, Wahn U, Keil T, Lau S, Matricardi PM Pediatr Allergy Immunol. 2014 Jun;25(4):366-73. doi: 10.1111/pai.12248. PMID: 24953296

    zur Publikation
  • Predictive values of component-specific IgE for the outcome of peanut and hazelnut food challenges in children.

    Beyer K1, Grabenhenrich L, Beder A, Kalb B, Ziegert M, Finger A, Harandi N, Schlags R, Gappa M, Puzzo L, Röblitz H, Millner-Uhlemann M, Büsing S, Ott H, Lange L, Niggemann B Allergy. 2014 Oct 13. doi: 10.1111/all.12530. [Epub ahead of print] PMID: 25308885

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  • Factors augmenting allergic reactions.

    Niggemann B1, Beyer K Allergy. 2014 Dec;69(12):1582-7. doi: 10.1111/all.12532. PMID: 25306896

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  • The fraction of varicella zoster virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with varicella zoster virus reactivation and multiple sclerosis.

    Otto C, Hofmann J, Finke C, Zimmermann M, Ruprecht K. Fluids Barriers CNS. 2014 Feb 12. PMID: 24517462

    zur Publikation
  • Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection.

    Frenzel K, Lehmann J, Krüger DH, Martin-Parras L, Uharek L, Hofmann J. Med Microbiol Immunol. 2014 Apr;203(2):115-23. PMID: 24337366.

  • Hantavirus disease in Germany due to infection with Dobrava-Belgrade virus genotype Kurkino. Clin Microbiol Infect.

    Hofmann J, Meier M, Enders M, Führer A, Ettinger J, Klempa B, Schmidt S, Ulrich RG, Kruger DH. 2014 Oct;20(10):O648-55. PMID: 24438436.

  • An ORF1-rearranged hepatitis E virus derived from a chronically infected patient efficiently replicates in cell culture.

    Johne R, Reetz J, Ulrich RG, Machnowska P, Sachsenröder J, Nickel P, Hofmann J. J Viral Hepat. 2014 Jun;21(6):447-56. PMID: 24750215.

  • Parvovirus B19 genotype 2 in blood donations.

    Eis-Hübinger AM, Reber U, Edelmann A, Kalus U, Hofmann J. Transfusion. 2014 Jun;54(6):1682-4. PMID: 24911910.

  • Multiple sclerosis: the elevated antibody response to Epstein-Barr virus primarily targets, but is not confined to, the glycine-alanine repeat of Epstein-Barr nuclear antigen-1.

    Ruprecht K, Wunderlich B, Gieß R, Meyer P, Loebel M, Lenz K, Hofmann J, Rosche B, Wengert O, Paul F, Reimer U, Scheibenbogen C. J Neuroimmunol. 2014 Jul 15;272(1-2):56-61. PMID: 24798244.

  • β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps.

    Raftery MJ, Lalwani P, Krautkrӓmer E, Peters T, Scharffetter-Kochanek K, Krüger R, Hofmann J, Seeger K, Krüger DH, Schönrich G. J Exp Med. 2014 Jun 30;211(7):1485-97. PMCID: 4076588.

  • A zoonotic viral threat: news about hantavirus disease.

    Krüger DH, Hofmann J, Krautkrämer E, Zeier M. Dtsch Med Wochenschr. 2014 Aug;139(31-32):1576-8. PMID: 25076309.

  • Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis.

    Kill A, Tabeling C, Undeutsch R, Kühl AA, Günther J, Radic M, Becker MO, Heidecke H, Worm M, Witzenrath M, Burmester GR, Dragun D, Riemekasten G Arthritis Res Ther. 2014 Jan 28;16(1):R29. doi: 10.1186/ar4457. PMID: 24472528

    zur Publikation
  • Vascular receptor autoantibodies in pulmonary arterial hypertension associated with systemic sclerosis.

    Becker MO1, Kill A, Kutsche M, Guenther J, Rose A, Tabeling C, Witzenrath M, Kühl AA, Heidecke H, Ghofrani HA, Tiede H, Schermuly RT, Nickel N, Hoeper MM, Lukitsch I, Gollasch M, Kuebler WM, Bock S, Burmester GR, Dragun D, Riemekasten G Am J Respir Crit Care Med. 2014 Oct 1;190(7):808-17. doi: 10.1164/rccm.201403-0442OC. PMID: 25181620

    zur Publikation
  • Rheumatoid factor or antinuclear antibodies as incidental finding.

    Biesen R1, Burmester GR, Hiepe F Internist (Berl). 2014 Oct;55(10):1157-64. doi: 10.1007/s00108-014-3588-5. PMID: 25269385

    zur Publikation
  • High prevalence of Immunoglobulin Light Chain Gene rearrangements as revealed by FISH in Multiple Myeloma and MGUS.

    Türkmen S, Binder A, Gerlach A, Niehage S, Faber J, Melissari MT, Inandiklioglu N, Dörken B, Burmeister T Genes, Chromosomes and Cancer 2014;53:650-6. PMID: 24729354.

    zur Publikation
  • Germline variants in IKZF1, ARID5B, and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group.

    Burmeister T, Gröger D, Bartels G, Trautmann H, Schwartz S, Lenz K, Tietze-Bürger C, Viardot A, Wäsch R, Horst HA, Reinhardt R, Gökbuget N, Hoelzer D, Kneba M, Brüggemann M haematologica 2014; 99:e23-e25. PMID:24497567.

    zur Publikation
  • Hypomorphic, homozygous mutations in Phosphoglucomutase 3 impair immunity and increase serum IgE levels.

    Sassi A, Lazaroski S, Wu G, Haslam SM, Fliegauf M, Mellouli F, Patiroglu T, Unal E, Ozdemir MA, Jouhadi Z, Khadir K, Ben-Khemis L, Ben-Ali M, Ben-Mustapha I, Pfeifer D, Jakob T, Khemiri M, Asplund CA, Gustafsson MO, Lundin KE, Falk-Sörqvist E, Moens LN, Gungor HE, Engelhardt KR, Dziadzio M, Stauss H, Fleckenstein B, Meier R, Prayitno K, Maul-Pavicic A, Schaffer S, Rakhmanov M, Henneke P, Kraus H, Eibel H, Kölsch U, Nadifi S, Nilsson M, Bejaoui M, Schäffer AA, Edvard Smith CI, Dell A, Barbouche MR, Grimbacher B J All Clin Immunol – J Allergy Clin Immunol. 2014 May;133(5):1410-9.

  • Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation.

    Howard MF, Murakami Y, Pagnamenta AT, Daumer-Haas C, Fischer B, Hecht J, Keays DA, Knight SJ, Kölsch U, Krüger U, Leiz S, Maeda Y, Mitchell D, Mundlos S, Phillips JA 3rd, Robinson PN, Kini U, Taylor JC, Horn D, Kinoshita T, Krawitz PM. Am J Hum Genet. 2014 Feb 6;94(2):278-87.

  • Deficient EBV-specific B- and T-cell response in patients with chronic fatigue syndrome.

    Loebel M, Strohschein K, Giannini C, Koelsch U, Bauer S, Doebis C, Thomas S, Unterwalder N, von Baehr V, Reinke P, Knops M, Hanitsch LG, Meisel C, Volk HD, Scheibenbogen C PLoS One. 2014 Jan 15;9(1):e85387. doi: 10.1371/journal.pone.0085387. eCollection 2014. PMID: 24454857

    zur Publikation
  • Liver abscess complicated by diaphragm perforation and pleural empyema leads to the discovery of interleukin-1 receptor-associated kinase 4 deficiency.

    Schöndorf D, von Bernuth H, Simon A, Schneider G, Kölsch U, Schwarz K, Meier CM, Groe-Onnebrink J, Gortner L, Rohrer TR Pediatr Infect Dis J. 2014 Jul;33(7):767-9. doi: 10.1097/INF.0000000000000277. PMID: 24717963

    zur Publikation
  • Effective treatment with intravenous immunoglobulins reduces autoreactive T-cell response in patients with CIDP.

    Klehmet J, Goehler J, Ulm L, Kohler S, Meisel C, Meisel A, Harms H J Neurol Neurosurg Psychiatry. 2014 Jul 29. pii: jnnp-2014-307708. doi: 10.1136/jnnp-2014-307708. Epub 2014 Jul 29 PMID: 25074566

    zur Publikation
  • Combined immunodeficiency develops with age in Immunodeficiency-centromeric instability-facial anomalies syndrome 2 (ICF2).

    von Bernuth H, Ravindran E, Du H, Fröhler S, Strehl K, Krämer N, Issa-Jahns L, Amulic B, Ninnemann O, Xiao MS, Eirich K, Kölsch U, Hauptmann K, John R, Schindler D, Wahn V, Chen W, Kaindl AM Orphanet J Rare Dis. 2014 Oct 21;9(1):116. doi: 10.1186/s13023-014-0116-6 PMID: 25330735

    zur Publikation
  • Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis.

    Schefold JC, Porz L, Uebe B, Poehlmann H, von Haehling S, Jung A, Unterwalder N, Meisel C J Perinat Med. 2014 Oct 25. pii: /j/jpme.ahead-of-print/jpm-2014-0226/jpm-2014-0226.xml. doi: 10.1515/jpm-2014-0226. PMID: 25418981

    zur Publikation
  • High prevalence of immunoglobulin light chain gene aberrations as revealed by FISH in multiple myeloma and MGUS.

    Türkmen S, Binder A, Gerlach A, Niehage S, Theodora Melissari M, Inandiklioglu N, Dörken B, Burmeister T Genes Chromosomes Cancer. 2014 Aug;53(8):650-6. PMID: 24729354

    zur Publikation
  • Copy number genome alterations are associated with treatment response and outcome in relapsed childhood ETV6/RUNX1-positive acute lymphoblastic leukemia.

    Bokemeyer A, Eckert C, Meyr F, Koerner G, von Stackelberg A, Ullmann R, Türkmen S, Henze G, Seeger K Haematologica. 2014 Apr;99(4):706-14. PMID: 24241490

    zur Publikation
  • Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome.

    Zemojtel T, Köhler S, Mackenroth L, Jäger M, Hecht J, Krawitz P, Graul-Neumann L, Doelken S, Ehmke N, Spielmann M, Christine Øien N, Schweiger M, Krüger U, Frommer G, Fischer B, Kornak U, Flöttmann R, Ardeshirdavani A, Moreau Y, Lewis S, Haendel S, Smedley D, Horn D, Mundlos S, Robinson P Science Translational Medicine, 2014 Sep 3;6(252):252ra123. PMID: 3009262

    zur Publikation
  • Cupulin is a zona pellucida-like domain protein and major component of the cupula from the inner ear.

    Dernedde J, Weise C, Müller EC, Hagiwara A, Bachmann S, Suzuki M, Reutter W, Tauber R, Scherer H PLoS One 2014 Nov 4;9(11):e111917. doi: 10.1371/journal.pone.0111917. eCollection 2014.

  • Rapid Analysis of Cell Surface N-Glycosylation from Living Cells Using Mass Spectrometry.

    Hamouda H, Kaup M, Ullah M, Berger M, Sandig V, Tauber R, Blanchard V. J Proteome Res. 2014;13(12): 6144-51.

  • Improving compliance to colorectal cancer screening using blood and stool based tests in patients refusing screening colonoscopy in Germany.

    Adler A, Geiger S, Keil A, Bias H, Schatz P, deVos T, Dhein J, Zimmermann M, Tauber R, Wiedenmann B. BMC Gastroenterol. 2014 Oct 17;14:183. doi: 10.1186/1471-230X-14-183.

  • Identification of 34 N-glycan isomers in human serum by capillary elec-trophoresis coupled with laser-induced fluorescence allows improving glycan biomarker discovery.

    Schwedler C, Kaup M, Weiz S, Hoppe M, Braicu EI, Sehouli J, Hoppe B, Tauber R, Berger M, Blanchard V. Anal. Bioanal. Chem. 2014 Nov;406(28):7185-93. doi: 10.1007/s00216-014-8168-y. Epub 2014 Sep 19.

  • The Serum Glycome to Discriminate between Early-Stage Epithelial Ovarian Cancer and Benign Ovarian Diseases

    Karina Biskup, Elena Iona Braicu, Jalid Sehouli, Rudolf Tauber, and Véronique Blanchard Disease Markers, Volume 2014 (2014), Article ID 238197, 10 pages

    zur Publikation
  • The fraction of varicella zos-ter virus-specific antibodies among all intrathecally-produced antibodies discriminates between patients with Varicella zoster virus reactivation and multiple sclerosis.

    Otto C., Hofmann J., Finke C., Zimmermann M., Ruprecht K. Fluid and Barriers of the CNS 11: 1-3 (2014)

  • Sialic acid methylation refines capillary electrophoresis laser-induced fluorescence analyses of immunoglobulin G N-glycans of ovarian cancer patients.

    Schwedler C, Kaup M, Petzold D, Hoppe B, Braicu EI, Sehouli J, Ehlers M, Berger M, Tauber R, Blanchard V. Electrophoresis. 2014 Apr;35(7):1025-31.

  • European Academy of Allergy and Clinical Immunology Section on Pediatrics.

    Eigenmann PA, Atanaskovic-Markovic M, O’B Hourihane J, Lack G, Lau S, Matricardi PM, Muraro A, Namazova Baranova L, Nieto A, Papadopoulos NG, Réthy LA, Roberts G, Rudzeviciene O, Wahn U, Wickman M, Høst A; European Academy of Allergy and Clinical Immunology-Clemens von Pirquet Foundation: Testing children for allergies: why, how, who and when: an updated statement of the European Academy of Allergy and Clinical Immunology (EAACI) Section on Pediatrics and the EAACI-Clemens von Pirquet Foundation. Pediatr Allergy Immunol. 2013 Mar;24(2):195-209. doi: 10.1111/pai.12066. Review. PMID: 23506293

    zur Publikation
  • DUAL study group: Transient impact of omalizumab in pollen allergic patients undergoing specific immunotherapy.

    Kopp MV, Hamelmann E, Bendiks M, Zielen S, Kamin W, Bergmann KC, Klein C, Wahn U Pediatr Allergy Immunol. 2013 Aug;24(5):427-33. doi: 10.1111/pai.12098. Epub 2013 Jun 25. PMID:23799935

    zur Publikation
  • The value of specific IgE to peanut and its component Ara h 2 in the diagnosis of peanut allergy.

    Lopes de Oliveira LC, Aderhold M, Brill M, Schulz G, Rolinck-Werninghaus C, Clare Mills EN, Niggemann B, Naspitz CK, Wahn U, Beyer K. J Allergy Clin Immunol Pract. 2013 Jul-Aug;1(4):394-8. doi:10.1016/j.jaip.2013.05.010. Epub 2013 Jun 28. PMID: 24565545

    zur Publikation
  • Vitamin D in early life: good or bad for food allergies?

    Querfeld U, Keil T, Beyer K, Stock P, Pilz S, März W, Weisse K, Lehmann I Allergy. 2013 Aug;68(8):1081-3. doi: 10.1111/all.12178. No abstract available. PMID:23968384

    zur Publikation
  • Molecular profile clustering of IgE responses and potential implications for specific immunotherapy.

    Matricardi PM Curr Opin Allergy Clin Immunol. 2013 Aug;13(4):438-45. doi: 10.1097/ACI.0b013e3283630ca5. PMID: 23799338

    zur Publikation
  • Staphylococcus aureus enterotoxin-specific IgE is associated with asthma in the general population: a GA(2)LEN study.

    Tomassen P, Jarvis D, Newson R, Van Ree R, Forsberg B, Howarth P, Janson C, Kowalski ML, Krämer U, Matricardi PM, Middelveld RJ, Todo-Bom A, Toskala E, Thilsing T, Brożek G, Van Drunen C, Burney P, Bachert C Allergy. 2013 Oct;68(10):1289-97. doi: 10.1111/all.12230. Epub 2013 Oct 5. PMID: 24117882

    zur Publikation
  • Italian Pediatric Allergy Network (I-PAN): Pollen-induced allergic rhinitis in 1360 Italian children: Comorbidities and determinants of severity.

    Dondi A, Tripodi S, Panetta V, Asero R, Businco AD, Bianchi A, Carlucci A, Ricci G, Bellini F, Maiello N, Miraglia Del Giudice M, Frediani T, Sodano S, Dello Iacono I, Macrì F, Massaccesi V, Caffarelli C, Rinaldi L, Patria MF, Varin E, Peroni D, Chinellato I, Chini L, Moschese V, Lucarelli S, Bernardini R, Pingitore G, Pelosi U, Tosca M, Paravati F, La Grutta S, Meglio P, Calvani M, Plebani M, Matricardi PM Pediatr Allergy Immunol. 2013 Dec;24(8):742-51. doi: 10.1111/pai.12136. Epub 2013 Nov 17. PMID:24236692

    zur Publikation
  • N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis.

    Prüss H, Finke C, Höltje M, Hofmann J, Klingbeil C, Probst C, Borowski K, Ahnert-Hilger G, Harms L, Schwab JM, Ploner CJ, Komorowski L, Stoecker W, Dalmau J, Wandinger KP. Ann Neurol. 2012; 72(6):902-11. PMID: 23280840

    zur Publikation
  • Performance of the MagNA Pure 96 System for Cytomegalovirus Nucleic Acid Amplification Testing in Clinical Samples.

    Edelmann A, Eichenlaub U, Lepek S, Krüger DH, Hofmann J. J Clin Microbiol. 2013; 51(5):1600-1. PMID: 23467597

    zur Publikation
  • Novel Polyomaviruses of Nonhuman Primates: Genetic and Serological Predictors for the Existence of Multiple.

    Scuda N, Madinda NF, Akoua-Koffi C, Adjogoua EV, Wevers D, Hofmann J, Cameron KN, Leendert SAJ, Couacy-Hymann E, Robbins M, Boesch C, Jarvis MA, Moens U, Mugisha L, Calvignac-Spencer S, Leendertz FH, Ehlers B PLoS Path. 2013; 9(6):e 1003429. PMID: 23818846

    zur Publikation
  • Are there Epstein-Barr virus seronegative patients with multiple sclerosis?

    Deuschle K, Hofmann J, Otto C, Bellmann-Strobl J, Scherner O, Klumbies K, Schneider E, Broddack J, Paul F, Ruprecht K. Mult Scler. 2013 Jan 10. [Epub ahead of print] PMID: 23307904

    zur Publikation
  • Identification of a novel human polyomavirus in organs of the gastrointestinal tract.

    Korup S, Rietscher J, Calvignac-Spencer S, Trusch F, Hofmann J, Moens U, Sauer I, Voigt S, Schmuck R, Ehlers B. PLoS One. 2013; 8(3):e58021. PMID: 23516426

    zur Publikation
  • A self-recombinant hepatitis E virus derived from a chronically infected patient efficiently replicates in cell culture.

    Johne R, Reetz J, Ulrich RG, Machnowska P, Sachsenröder J, Nickel P, Hofmann J. J viral Hepat. June 2013 accepted

  • Organversagen und Hantavirus-Infektion: Ein in Deutschland noch unterschätzter Krankheitserreger.

    Krüger DH, Ulrich RG, Hofmann J. Deutsches Ärzteblatt 2013, Juli

  • Hantaviren als zoonotische Krankheitserreger in Deutschland.

    Krüger, Detlev H.; Ulrich, Rainer G.; Hofmann, J Deutsches Ärzteblatt Int 2013

  • Neurosarcoidosis: correlation of cerebrospinal fluid findings with diffuse leptomeningeal gadolinium enhancement on MRI and clinical disease activity.

    Wengert O, Rothenfusser-Korber E, Vollrath B, Bohner G, Scheibe F, Otto C, Hofmann J, Angstwurm K, Ruprecht K. J Neurol Sci. 2013; 15;335(1-2):124-130 PMID: 24071064

    zur Publikation
  • Combination of immunoglobulins and natural killer cells in the context of CMV and EBV infection.

    Frenzel K, Lehmann J, Krüger DH, Martin-Parras L, Uharek L, Hofmann J. Med Microbiol Immunol. 2013 Dec 15. [Epub ahead of print] PMID: 24337366

    zur Publikation
  • ORAL Step investigators: Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial.

    Burmester GR, Blanco R, Charles-Schoeman C, Wollenhaupt J, Zerbini C, Benda B, Gruben D, Wallenstein G, Krishnaswami S, Zwillich SH, Koncz T, Soma K, Bradley J, Mebus C Lancet. 2013 Feb 9;381(9865):451-60. doi: 10.1016/S0140-6736(12)61424-X. Epub 2013 Jan 5. PMID:23294500

    zur Publikation
  • Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response.

    Enghard P, Rieder C, Kopetschke K, Klocke JR, Undeutsch R, Biesen R, Dragun D, Gollasch M, Schneider U, Aupperle K, Humrich JY, Hiepe F, Backhaus M, Radbruch AH, Burmester GR, Riemekasten G Ann Rheum Dis. 2014 Jan 1;73(1):277-83. doi: 10.1136/annrheumdis-2012-202784. Epub 2013 Mar 8. PMID:23475982

    zur Publikation
  • Peripheral blood sCD3- CD4+ T cells: a useful diagnostic tool in angioimmunoblastic T cell lymphoma.

    Singh A, Schabath R, Ratei R, Stroux A, Klemke CD, Nebe T, Flörcken A, van Lessen A, Anagnostopoulos I, Dörken B, Ludwig WD, Pezzutto A, Westermann J. Hematol Oncol. 2013 Jun 24. PMID:23798351

    zur Publikation
  • Even in Pneumococcal Sepsis CD62L Shedding on Granulocytes Proves to be a Reliable Functional Test for the Diagnosis of Interleukin-1 Receptor Associated Kinase 4 Deficiency.

    Andres O, Strehl K, Kölsch U, Kunzmann S, Lebrun AH, Stroh T, Schwarz K, Morbach H, von Bernuth H, Liese J Pediatr Infect Dis J. 2013 Mar 27. [Epub ahead of print] PMID:23538514

    zur Publikation
  • Impaired thymic function and CD4+ T lymphopenia, but not mannose-binding lectin deficiency, are risk factors for Pneumocystis jirovecii pneumonia in kidney transplant recipients.

    Schürmann M, Schürmann D, Schindler R, Meisel C, Liman P, Kruse J, Enghard P, König J, Schmidt D, Reinke P, Nickel P Transpl Immunol. 2013 Jun;28(4):159-63. doi: 10.1016/j.trim.2013.05.003. Epub 2013 May 15. PMID:23684946

    zur Publikation
  • Terminally differentiated CD8⁺ T cells negatively affect bone regeneration in humans.

    Reinke S, Geissler S, Taylor WR, Schmidt-Bleek K, Juelke K, Schwachmeyer V, Dahne M, Hartwig T, Akyüz L, Meisel C, Unterwalder N, Singh NB, Reinke P, Haas NP, Volk HD, Duda GN Sci Transl Med. 2013 May 29;5(187):187er4. PMID:23515078

    zur Publikation
  • Konnatale Pneumonie und pustulöse Hautveränderungen bei einem männlichen Säugling.

    Leisering J, Renner E.D, von Bernuth H, Wahn V, Rossi R Monatsschrift Kinderheilkunde 8. 2013, Juni

  • Elevation of CD4+ differentiated memory T cells is associated with acute cellular and antibody-mediated rejection after liver transplantation.

    Gerlach UA, Vogt K, Schlickeiser S, Meisel C, Streitz M, Kunkel D, Appelt C, Ahrlich S, Lachmann N, Neuhaus P, Pascher A, Sawitzki B Transplantation. 2013 Aug 27;96(4):e33. PMID:23619734

    zur Publikation
  • Messunsicherheit und Qualitätssicherung im Bereich der Immunphänotypisierung der Lymphozytensubpopulationen im peripheren Blut.

    Nebe, Carl Thomas; Dorn-Beineke, Alexandra; Braun, Patrick; Daniel, Volker; Ilieva, Zhana; Kuling, Gudrun; Meisel, Christian; Oelschlägel, Uta; Sack, Ulrich Follow LaboratoriumsMedizin, Volume 37 (5) de Gruyter – Sep 1, 2013

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  • Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study.

    Streitz M, Miloud T, Kapinsky M, Reed MR, Magari R, Geissler EK, Hutchinson JA, Vogt K, Schlickeiser S, Kverneland AH, Meisel C, Volk HD, Sawitzki B Transplant Res. 2013 Oct 25;2(1):17. [Epub ahead of print] PMID:24160259

    zur Publikation
  • Discrimination of T-cell subsets and T-cell receptor repertoire distribution.

    Bretschneider I, Clemente MJ, Meisel C, Guerreiro M, Streitz M, Hopfenmüller W, Maciejewski JP, Wlodarski MW, Volk HD Immunol Res. 2013 Nov 23. PMID: 24272857

    zur Publikation
  • Blood transfusion determines postoperative morbidity in pediatric cardiac surgery applying a comprehensive blood-sparing approach.

    Redlin M., Kukucka M., Boettcher W., Schoenfeld H., Huebler M., Kuppe H. & Habazettl H. J Thorac Cardiov Sur. 2013;146(3):537-42.

  • Reply to the editor.

    Redlin M., Kukucka M., Boettcher W., Schoenfeld H., Huebler M., Kuppe H. & Habazettl H. J Thorac Cardiov Sur. 2013;145(6):1680-1.

  • N-glycosylation profile of undifferentiated and adipogenically differentiated human bone marrow mesenchymal stem cells: towards a next generation of stem cell markers.

    Hamouda H, Ullah M, Berger M, Sittinger M, Tauber R, Ringe J, Blanchard V. Stem Cells Dev. 2013 Dec 1;22(23):3100-13. doi: 10.1089/scd.2013.0108. Epub 2013 Aug 20.

  • Cellular origin and diag-nostic signficance of high-fluorescent cells in cerebrospinal fluid detected by the XE-5000 hematology analylzer.

    Zimmermann M., Otto C., Gonzalez J.-B., Prokop S., Ruprecht K. Int J Lab Hematology, S. 1-9 (2013)

  • Developement and Analy-sis of Alpha1-Antitrypsin Neoglycoproteins: The Impact of Additional N-Glycosylation Sites on Serum Half-Life.

    Lusch A., Kaup M., Marx U., Tauber R., Blanchard V., Berger M. Mol Pharm. 2013 Jul 1;10(7):2616-29. doi: 10.1021/mp400043r. Epub 2013 May 30.

  • Targeting density-enhanced phosphatase-1 (DEP-1) with anti-sense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice.

    Krüger J, Trappiel M, Dagnell M, Stawowy P, Meyborg H, Böhm C, Bhanot S, Ostman A, Kintscher U, Kappert K.

  • Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity.

    Kappert K, Meyborg H, Fritzsche J, Urban D, Krüger J, Wellnhofer E, Kintscher U, Fleck E, Stawowy P. PLoS One 6, 8 (8):e70542 (2013) Cell Commun Signal. 2013 Jul 26;11(1):49. [Epub ahead of print]

  • Knockout of Density-Enhanced Phosphatase-1 impairs cerebrovascular reserve capacity in an arteriogenesis model in mice.

    Hackbusch D, Dülsner A, Gatzke N, Krüger J, Hillmeister P, Nagorka S, Blaschke F, Ritter Z, Thöne-Reineke C, Böhmer FD, Buschmann I, Kappert K. Biomed Res Int. 2013

  • Endo-ß-N-acetylglucosaminidase H de N-glycosylation in a domestic microwave oven: application to biomarker discovery.

    Frisch E., Schwedler C., Kaup M., Iona Braicu E., Gröne J., Lauscher JC, Sehouli J., Zim-mermann M., Tauber R., Berger M., Blanchard V. Anal Biochem 433: 65-69 (2013)

  • Serum glycome profiling – a biomarker for diagnosis of ovarian cancer.

    Biskup K, Braicu EI, Sehouli J, Fotopoulou C, Tauber R, Berger M and Blanchard V J Prot Res. 12 (9):4056-63 2013).

  • Specific immunotherapy with allergens: an important tool in the treatment of the allergic diseases.

    Zuberbier T, Canonica GW, da Silva B J Dtsch Dermatol Ges. 2012 Dec;10(12):879-85. doi: 10.1111/j.1610-0387.2012.08017.x. Epub 2012 Oct 17. English, German. PMID:23072584

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  • Measles IgG antibody index correlates with T2 lesion load on MRI in patients with early multiple sclerosis.

    Rosche B, Laurent S, Conradi S, Hofmann J, Ruprecht K, Harms L. PLoS One 2012, 7(1): e28094 PMID: 22276094 PMCID: PMC3261854

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  • Von Mäusen auf Menschen – Erkenntnisse aus der Hantavirus-Epidemie 2010.

    Loyen M, Helmchen U, Hofmann J, Krüger DH, Clasen W. Dtsch Med Wochenschr 2012, 1370: 309–313 PMID: 22318843

    zur Publikation
  • Antiviral function and efficacy of polyvalent immunoglobulin products against CMV isolates in different human cell lines.

    Frenzel K., Ganepola S., Michel D., Thiel E., Krüger DH., Uharek L. und Hofmann J. (2012) Med Microbiol Immunol 2012; Epub ahead. PMID: 22297735

    zur Publikation
  • Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs.

    Dremsek P, Wenzel JJ, Johne R, Ziller M, Hofmann J, Groschup MH, Werdermann S, Mohn U, Dorn S, Motz M, Mertens M, Jilg W, Ulrich RG. Med Microbiol Immunol 2012; 201:189–200 PMID: 22179131

    zur Publikation
  • Evaluation of Three Commercial Varicella-Zoster Virus IgG Enzyme-Linked Immunosorbent Assays in Comparison to the Fluorescent-Antibody-to-Membrane-Antigen Test.

    Sauerbrei A, Schäfler A, Hofmann J, Schacke M, Gruhn P, Wutzler P. Clin. Vaccine Immunol. 2012, 19(8):1261. PMID: 22718131

    zur Publikation
  • Hyperintense lesion in the corpus callosum associated with Puumala hantavirus infection.

    Steiner T, Ettinger J, Peng Z, Hofmann J, Hartmann M, Burkhardt M, Schnitzler P. J Neurol 2012; 259(8): PMID: 22349863

    zur Publikation
  • Atypical severe Puumala hantavirus infection with virus sequence analysis from the patient and regional reservoir host.

    Eckerle I, Jakob E, Hofmann J, Schmidt-Bacher A, Ettinger J, Schnitzler P. Zoonoses and Public Health 2012; 59(s2): 110–5 PMID: 22958255

    zur Publikation
  • Multiple synchronous outbreaks of puumala virus, Germany, 2010.

    Ettinger J., Hofmann J., Enders M., Tewald F., Oehme R.M., Rosenfeld U.M., Ali H.S., Schlegel M., Essbauer S., Osterberg A., Jacob J., Reil D., Klempa B., Ulrich R.G., Kruger D.H. (2012) Emerg Infect Dis. 2012 Sep;18(9):1461-4. PMID: 22932394

    zur Publikation
  • Dobrava hantavirus infection with panhypopituitarism, Istanbul-Turkey.

    Sarıgüzel N*, Hofmann J*, Canpolat AT, Türk A, Ettinger J, Atmaca D, Akyar I, Yücel S, Arıkan E, Uyar Y, Çağlayık DY, Kocagöz AS, Kaya A, Kruger DH. Emerg Infect Dis 2012; 18(7): 1180-3 (* equally contributed) PMID: 22709722

    zur Publikation
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    Hofmann J, Führer A, Bolz M, Waldschläger-Terpe J, Meier M, Lüdders D, Enders M, Oltmann A, Meisel H, Krüger DH. J Clin Virol. 2012; 55(3): 266-9

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    Liman P, Babel N, Schachtner T, Unterwalder N, Konig J, Hofmann J, Reinke P, Nickel P Transpl Immunol 2012; 26(2-3): 123-127

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    Führer A, Bolz M, Hofmann J. Dtsch Med Wochenschr 2012, 137: 2369–2372 PMID: 23132155

    zur Publikation
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    zur Publikation
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    zur Publikation
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    zur Publikation
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    zur Publikation
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    zur Publikation
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    Nguyen-Hoai T, Baldenhofer G, Ahmed MS, Pham-Duc M, Gries M, Lipp M, Dörken B, Pezzutto A, Westermann J. J Gene Med. 2012;14:128-37. PMID: 22228591

    zur Publikation
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    Kroenlein H, Schwartz S, Reinhardt R, Rieder H, Molkentin M, Gökbuget N, Hoelzer D, Thiel E, Burmeister T. Genes Chromosomes Cancer. 2012;51:290-9. PMID: 22120970

    zur Publikation
  • Molecular investigation of Ewing sarcoma: about detecting translocations.

    Blau O. EMBO Molecular Medicine 2012;4:1-2 PMID: 22467249

    zur Publikation
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    zur Publikation
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    Von Haehling S, Schefold JC, Jankowska EA, Springer J, Vazir A, Kalra PR, Sandek A, Fauler G, Stojakovic T, Trauner M, Ponikowski P, Volk HD, Doehner W, Coats AJ, Poole-Wilson PA, Anker SD J Am Coll Cardiol. 2012 Feb 7;59(6):585-92. PMID:22300693

    zur Publikation
  • Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis.

    Yang CA, Raftery MJ, Hamann L, Guerreiro M, Grütz G, Haas D, Unterwalder N, Schönrich G, Schumann RR, Volk HD, Scheibenbogen C Hum Immunol. 2012 Aug 73(8):844-51. doi: 10.1016/j.humimm.2012.04.008. Epub 2012 Apr 23. PMID:22537752

    zur Publikation
  • Expermental and natural infections in MyD88- and IRAK-4-deficient mice and humans.

    Bernuth von H, Picard C, Puel A, Casanova J-L Eur. J. Immunol. 2012. 42: 3126-3135.

    zur Publikation
  • Involvement of the MLL gene in adult T-lymphoblastic leukemia.

    Türkmen S, Timmermann B, Bartels G, Gröger D, Meyer C, Schwartz S, Haferlach C, Rieder H, Gökbuget N, Hoelzer D, Marschalek R, Burmeister T Genes Chromosomes Cancer, Dec 2012;51(12):1114-24. PMID 22927255

    zur Publikation
  • MLPA-based evidence for sequence gain: pitfalls in confirmation and necessity for exclusion of false positives.

    Varga R.E., Mumtaz R., Jahic A., Rudenskaya G.E., Sánchez-Ferrero E., Auer-Grumbach M., Hübner C.A. & Beetz C. Anal Biochem. 2012;421(2):799-801.

  • First HPSE2 missense mutation in urofacial syndrome.

    Mahmood S., Beetz C., Tahir M.M., Imran M., Mumtaz R., Bassmann I., Jahic A., Malik M., Nürnberg G., Hassan S.A.A., Rana S., Nürnberg P. & Hübner C.A. Clin Genet. 2012;81(1):88-92.

  • High prevalence of anti-HCV antibodies in two metropolitan emergency rooms in Germany: a prospective screening analysis of 28,809 patients.

    Vermehren J, Schlosser B, Domke D, Elanjimattom S, Müller C, Hintereder G, Hensel-Wiegel K, Tauber R, Berger A, Haas N, Walcher F, Möckel M, Lehmann R, Zeuzem S, Sar-razin C, Berg T. PLoS One. 2012;7(7):e41206. Epub 2012 Jul 25.

  • L-Selectin – A dynamic regulator of leukocyte mi-gration.

    Wedepohl S., Beceren-Braun F., Riese S., Buscher K., Enders S., Bernhard G., Kilian K., Blanchard V., Dernedde J., Tauber R. Eur J Cell Biol. 9:(4): 257-264 (2012)

  • Immature platelet count: a simple parameter for distinguishing thrombocytopenia in pediatric acute lymphocytic leukemia from immune thrombocytopenia.

    Strauss G., Vollert C., von Stackelberg A., Weimann A., Gaedicke G., Schulze H. Pediatr Blood Cancer: 57 (4): 641-647 (2012)

  • In vitro cytotoxicity of the novel antimyeloma agents perifosine, bortezomib and lenalidomide against different cell lines.

    Schmidt-Hieber M., Dabrowski R., Weimann A., Aicher B., Lohneis P., Busse A., Thiel E., Blau I.W. Invest New Drugs 30 (2): 480-489 (2012)

  • Impact of Sex on Cardiovascular Outcome in Patients at High Cardiovascular Risk.

    Kappert K., Böhm M., Schmieder R., Schumacher H., Teo K. Yusuf S., Sleight P., Unger T. Circulation 126: 934-941 (2012)

  • Coagulation and fibrin network formation: Beyond hemostatis and into inflammation.

    Hoppe B., Dörner T Nat Rev Rheumatol 8: 738-746 (2012)

  • Fibrinogen and factor XIII A-subunit genotypes interactively in-fluence C-reactive protein levels during inflammation.

    Hoppe B., Häupl T., Skapenko A., Ziemer A., Tauber R., Salama A., Schulze-Koops H., Bur-mester G.-R., Dörner T. Ann Rheum Dis 10: 1-7 (2012)

  • Thrombophilia screening in young patients with cryptogenic stroke. Prevalence of gene polymorphisms compared to healthy blood donors and impact on secondary stroke prevention.

    Häusler K.G., Herm J., Hoppe B., Kasakov R., Malzahn U., Endres M., Koscielny J., Jungehulsing G. J. Hämostaseologie 32: 147-52 (2012)

  • Biomarkers in rheumatology. Bi-omarkers and imaging for the diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the Arthro.

    Häupl T., Appel H., Backhaus M., Burkhardt H., Grünke M., Grützkau A., Hoppe, B., Listing J., Ostendorf B., Rudwaleit M., Sieper J., Skapenko A., Skriner K., Sörensen T., Stuhlmül-ler B., Zink A., Schulze-Koops H., Burmester G. R. Mark network funded by the Federal Ministry of Education and Research. Z Rheumatol 71: 314-8 (2012)

  • Subcutaneous immunotherapy and pharmacotherapy in seasonal allergic rhinitis: A comparison based on meta-analyses.

    Matricardi PM, Kuna P, Panetta V, Wahn U, Narkus A. (2011) J Allergy Clin Immunol. 2011 May 25.

  • Intrathecal EBV antibodies are part of the polyspecific immune response in multiple sclerosis.

    Otto C., Oltmann A., Stein A., Frenzel K., Schroeter J., Habbel P., Gartner B., Hofmann J.*, Ruprecht K.* (2011) Neurology 2011;76(15):1316-1321 (* equally contributed). PMID: 21482946

    zur Publikation
  • Pyrosequencing allows the detection of emergent ganciclovir resistance-mutations after HCMV infection.

    Kampmann SE., Schindele B., Apelt L., Bührer C., Garten L., Weizsaecker K., Krüger DH., Ehlers B., Hofmann J. (2011) Med Microbiol Immunol 2011; 200: 109-113. PMID: 21165648

    zur Publikation
  • Unmasking of autoreactive CD4 T cells by depletion of CD25 regulatory T cells in systemic lupus erythematosus.

    Engler JB., Undeutsch R., Kloke L., Rosenberger S., Backhaus M., Schneider U., Egerer K., Dragun D., Hofmann J., Huscher D., Burmester G-R., Humrich JY., Enghard P., Riemekasten G. (2011) Ann Rheum Dis 2011. 70(12):2176-83. PMID: 21926188

    zur Publikation
  • Evidence for the cure of HIV infection by CCR5{Delta}32/{Delta}32 stem cell transplantation.

    Allers K., Hutter G., Hofmann J., Loddenkemper C., Rieger K., Thiel E., Schneider T. (2011) Blood 2011; 117: 2791-2799. PMID: 21148083

    zur Publikation
  • Seroprevalence of the human polyomavirus 9 (1 HPyV9) and cross-reactivity to the African green monkey-derived lymphotropic polyomavirus (LPyV).

    Trusch F., Klein M., Finsterbusch T., Kühn J., Hofmann J.*, Ehlers B.* (2011) J Gen Virol 2011 (* equally contributed). PMID: 22218677

    zur Publikation
  • Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient.

    Schlosser B., Stein A., Neuhaus R., Pahl S., Ramez B., Kruger DH., Berg T., Hofmann J. (2011) J Hepatol 2011; epub ahead. PMID: 21798217

    zur Publikation
  • Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus.

    Barkhudarova F, Dähnrich C, Rosemann A, Schneider U, Stöcker W, Burmester GR, Egerer K, Schlumberger W, Hiepe F, Biesen R. Arthritis Res Ther 2011 Feb 10; 13(1):R20. PMID: 21329504

    zur Publikation
  • Anti-dsDNA-NcX ELISA: dsDNA-loaded nucleosomes improve diagnosis and monitoring of disease activity in systemic lupus erythematosus.

    Biesen R, Dähnrich C, Rosemann A, Barkhudarova F, Rose T, Jakob O, Bruns A, Backhaus M, Stöcker W, Burmester GR, Schlumberger W, Egerer K, Hiepe F. Arthritis Res Ther 2011 Feb 10; 13(1):R26. PMID: 21329504

    zur Publikation
  • Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay.

    Egerer K, Roggenbuck D, Büttner T, Lehmann B, Kohn A, von Landenberg P, Hiemann R, Feist E, Burmester GR, Dörner T. Arthritis Res Ther 2011 Jul 21; 13(4):R118. PMID: 21777436

    zur Publikation
  • Unmasking of autoreactive CD4 T cells by depletion of CD25 regulatory T cells in systemic lupus erythematosus.

    Engler JB, Undeutsch R, Kloke L, Rosenberger S, Backhaus M, Schneider U, Egerer K, Dragun D, Hofmann J, Huscher D, Burmester GR, Humrich JY, Enghard P, Riemekasten G. Ann Rheum Dis. 2011 Dec;70(12):2176-83. Epub 2011 Sep 16. PMID: 21926188

    zur Publikation
  • Profiling of Endo H-released serum N-glycans using CE-LIF and MALDI-TOF-MS–application to rheumatoid arthritis.

    Frisch E, Kaup M, Egerer K, Weimann A, Tauber R, Berger M, Blanchard V. Electrophoresis 2011 Dec; 32(24):3510-5. PMID: 22180205

    zur Publikation
  • Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.

    Westermann J, Flörcken A, Willimsky G, van Lessen A, Kopp J, Takvorian A, Jöhrens K, Lukowsky A, Schönemann C, Sawitzki B, Pohla H, Frank R, Dörken B, Schendel DJ, Blankenstein T, Pezzutto A. Gene Ther. 2011;18:354-63. PMID: 21068778

    zur Publikation
  • Endogenous filamentous fungal endophthalmitis – single center survey in patients with acute leukaemia or post allogeneic stem cell transplantation and review of the literature.

    Vergoulidou M, Krause L, Foerster MH, Thiel E, Schwartz S. (2011) Mycoses 2011; 54: e704. PMID: 21605192

    zur Publikation
  • A BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1.

    Türkmen S, Riehn M, Klopocki E, Molkentin M, Reinhardt R, Burmeister T. Genes Chromosomes Cancer. 2011;50(6):389-96. PMID: 21412927

    zur Publikation
  • Norovirus gastroenteritis causes severe and lethal complications after chemotherapy and hematopoietic stem cell transplantation.

    Schwartz S, Vergoulidou M, Schreier E, Loddenkemper C, Reinwald M, Schmidt-Hieber M, Flegel WA, Thiel E, Schneider T. (2011) Blood 2011, 117:5850-6. PMID: 21487110

    zur Publikation
  • The Efficacy of Voriconazole in the Treatment of 192 Fungal central nervous system infections – a retrospective analysis.

    Schwartz S, Reisman A, Troke PF. (2011) Infection 2011, 39: 201-10. PMID: 21512792

    zur Publikation
  • Allogeneic gene-modified tumor cells (RCC-26/IL-7/CD80) as a vaccine in patients with metastatic renal cell cancer: a clinical phase-I study.

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    zur Publikation
  • Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias.

    Burmeister T, Gröger D, Kühn A, Hoelzer D, Thiel E, Reinhardt R. DNA Repair (Amst). 2011;10:1131-7. PMID: 21944569

    zur Publikation
  • Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts.

    Blau O, Baldus CD, Hofmann WK, Thiel G, Nolte F, Burmeister T, Türkmen S, Benlasfer O, Schümann E, Sindram A, Molkentin M, Mundlos S, Keilholz U, Thiel E, Blau IW. Blood. 2011;118:5583-92. PMID: 21948175

    zur Publikation
  • Bone Marrow Microenviroment in the Pathogenesis of AML.

    Blau O. In: Koschmieder S, ed. Myeloid Leukemia-Basic Mechanisms of Leukemogenesis. InTech, 2011

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    zur Publikation
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    Hall, M.W., N.L. Knatz, C. Vetterly, S. Tomarello, M.D. Wewers, H.D. Volk, and J.A. Carcillo Intensive Care Med, 2011. 37(3): p. 525-32. PMID:21153402

    zur Publikation
  • Influence of stroke localization on autonomic activation, immunodepression, and post-stroke infection.

    Harms, H., P. Reimnitz, G. Bohner, T. Werich, R. Klingebiel, C. Meisel, and A. Meisel Cerebrovasc Dis, 2011. 32(6): p. 552-60. PMID:22104620

    zur Publikation
  • Efficient tetanus toxoid immunization on vitamin D supplementation.

    Heine, G., G. Drozdenko, A. Lahl, N. Unterwalder, H. Mei, H.D. Volk, T. Dorner, A. Radbruch and M. Worm Eur J Clin Nutr, 2011. 65(3): p. 329-34. PMID:21224870

    zur Publikation
  • Hyperbilirubinemia and rapid fatal hepatic failure in severe combined immunodeficiency caused by adenosine deaminase deficiency (ADA-SCID).

    Kuhl, J.S., K. Schwarz, A. Munch, M. Schmugge, A. Pekrun, C. Meisel, V. Wahn, W. Ebell, and H. von Bernuth Klin Padiatr, 2011. 223(2): p. 85-9. PMID:21271505

    zur Publikation
  • Suppressing immunosuppression after stroke.

    Meisel, C. and A. Meisel, N Engl J Med, 2011. 365(22): p. 2134-6. PMID:22129259

    zur Publikation
  • Immunodepression after aneurysmal subarachnoid hemorrhage.

    Sarrafzadeh, A., F. Schlenk, A. Meisel, J. Dreier, P. Vajkoczy, and C. Meisel Stroke, 2011. 42(1): p. 53-8. PMID:21088239

    zur Publikation
  • Tuberculin-specific T cells are reduced in active pulmonary tuberculosis compared to LTBI or status post BCG vaccination.

    Streitz, M., S. Fuhrmann, F. Powell, A. Quassem, L. Nomura, H. Maecker, P. Martus, H.D. Volk, and F. Kern J Infect Dis, 2011. 203(3): p. 378-82. PMID:21186260

    zur Publikation
  • BACH2-BCL2L1 fusion gene resulting from a t(6;20)(q15;q11.2) chromosomal translocation in the lymphoma cell line BLUE-1.

    Türkmen S, Riehn M, Klopocki E, Molkentin M, Reinhardt R, Burmeister T. A Genes Chromosomes Cancer, 2011 Jun;50(6):389-96. PMID 21412927

    zur Publikation
  • Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts.

    Blau O, Baldus CD, Hofmann WK, Thiel G, Nolte F, Burmeister T, Türkmen S, Benlasfer O, Schümann E, Sindram A, Molkentin M, Mundlos S, Keilholz U, Thiel E, Blau IW Blood, 2011 Nov 17;118(20):5583-92. Epub 2011 Sep 23. PMID 21948175

    zur Publikation
  • Construction and analysis of a novel peptide tag containing an unnatural N-glycosylation site.

    Kaup, Matthias, Saul,,Vera Vivian, Lusch, Astrid, Dörsing, Johanna, Blanchard, Véronique, Tauber, Rudolf and Berger, Markus FEBS Letters 585, 2372-2376 (2011)

  • N-glycosylation and biological activity of recombinant human alpha1-antitrypsin expressed in a novel human neuronal cell line.

    Véronique Blanchard, Xi Liu, Susann Eigel, Matthias Kaup, Silke Rieck, Sabina Janciauskiene, Volker Sanding, Uwe Marx, Peter Walden, Rudolf Tauber, and Markus Berger. Biotechnology and Bioengineering 108, 2118–2128 (2011)

  • Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines.

    Lieke T, Gröbe D, Blanchard V, Grunow D, Tauber R, Zimmermann-Kordmann M, Jacobs T, Reutter W. Glycoconj J. 28, 31 – 37 (2011)

  • Automated vs. Manual cerebrospinal fluid cell counts: a work and cost analysis comparing the Sysmex XE-5000 and the Fuchs-Rosenthal manual counting chamber.

    Zimmermann M., Ruprecht K., Kainzinger F., Heppner F.L., Weimann A. Int. J. Lab. Hematol. 33 (6): 629-637 (2011)

  • Granularity Index of the SYSMEX XE-5000 hematology analyzer as a replacement for manual microscopy of toxic granulation neutrophils in patients with inflammatory diseases.

    Zimmermann M., Cremer M., Hoffmann C., Weimann K., Weimann A. Clin. Chem. Lab. Med. 49 (6): 613-618 (2011)

  • Hypoxia Enhances Platelet-derived Growth Factor Signaling in the PUlmonary Vasculature by Down-Regulation of Protein Tyrosine Phosphatases.

    Ten Freyhaus H., Dagnell M., Leuchs M., Vantler M., Berghausen E.M., Caglayan E., Weissmann N., Dahal B.K., Schermuly R.T., Östman A., Kappert K., Rosenkranz S. Am J Respiratory and Critical Care Med. 183:1092-1102 (2011)

  • Immature platelet count: A simple parameter for distinguishing thrombocytopenia in pediatric acute lymphocytic leukemia from immune thrombocytopenia.

    Strauß G., Vollert C., von Stackelberg A., Weimann A., Gaedicke G., Schulze H. Pediatr Blood Cancer 57 (4): 641-647 (2011)

  • Prothrombin 20210G>A genotype and C-reactive protein level.

    Hoppe B., Burmester G. R., Häupl T. Blood 118: 4495-6 (2011)

  • Prothrombin 20210G>A genotype and C-reactive protein level.

    Hoppe B., Burmester GR., Häupl T. Blood 118: 4495-4496 (2011)

  • Adipose Tissue-Derived Soluble Fms-Like Tyrosine Kinase 1 is an Obesity-Relevant Endogenous Paracrine Adipokine.

    Herse F., Fain J.N., Janke J., Engeli S., Kuhn C., Frey N., Weich H.A., Bergmann A., Kappert K., Karumanchi S.A., Luft F.C., Muller D.N., Staff A.C., Dechen R. Hypertension 7: 37-42 (2011)

  • Profiling of Endo H-released serum N-glycans using CE-LIF and MALDI-TOF-MS-application to rheumatoid arthritis.

    Frisch E., Kaup M., Egerer K., Weimann A., Tauber R., Berger M., Blanchard V. Electrophoresis 32 (24): 3510-3515 (2011)

  • Disruption of Platelet-Derived Growth Factor-Dependent Phosphatidylinositol 3-Kinase and Phospholipase CУ1 Activity Abolishes Vascular Smooth Muscle Cell Proliferation and Migration and Attenuates Neointima Formation in Vivo.

    Caglayan E., Vantler M., Leppänen O., Gerhardt F., Mustafov L., ten Freyhaus H., Kappert K., Odenthal M., Zimmermann W., Tallquist M., Rosenkranz S. J of American College of Cardiology 57 (25): 2527-2538 (2011)

  • High-Dose Treatment with Telmisartan Induces Monocytic Peroxisome Proliferator-Activated Recepter-УTarget Genes in Patients with the Metabolic Syndrome.

    Bähr I., Tretter P., Krüger J., Stark R., Schimkus J., Unger T., Kappert K., Scholze J., Parhofer K., Kintscher U. Hypertension 58 (4): 725-732 (2011)

  • Humoral anti-proteasomal autoimmunity in dilated cardiomyopathy.

    Voigt A, Bartel K, Egerer K, Trimpert C, Feist E, Gericke C, Kandolf R, Klingel K, Kuckelkorn U, Stangl K, Felix SB, Baumann G, Kloetzel PM, Staudt A. Basic Res Cardiol 2010 Jan; 105(1):9-18. PMID: 19760349

    zur Publikation
  • Automated evaluation of autoantibodies on human epithelial-2 cells as an approach to standardize cell-based immunofluorescence tests.

    Egerer K, Roggenbuck D, Hiemann R, Weyer MG, Büttner T, Radau B, Krause R, Lehmann B, Feist E, Burmester GR. Arthritis Res Ther 2010; 12(2):R40. Epub 2010 Mar 9. PMID: 20214808

    zur Publikation
  • Lack of evidence for a pathogenic role of proteasome-directed autoimmunity in dilated cardiomyopathy.

    Voigt A, Trimpert C, Bartel K, Egerer K, Kuckelkorn U, Feist E, Gericke C, Klingel K, Kandolf R, Felix SB, Baumann G, Kloetzel PM, Stangl K, Staudt A. Basic Res Cardiol 2010 Jul; 105(4):557-67. Epub 2010 Mar 25. PMID: 20336303

    zur Publikation
  • Effects of early rituximab retreatment in rheumatoid arthritis patients with an inadequate response after the first cycle: retrospective arthritis cohort study.

    Bastian H, Zinke S, Egerer K, Breuer S, Safari F, Burmester GR, Feist E. J Rheumatol 2010 May; 37(5):1069-71. PMID: 20439529

    zur Publikation
  • Clinical and serological evaluation of a novel CENP-A peptide based ELISA.

    Mahler M, Maes L, Blockmans D, Westhovens R, Bossuyt X, Riemekasten G, Schneider S, Hiepe F, Swart A, Gürtler I, Egerer K, Fooke M, Fritzler MJ Arthritis Res Ther 2010; 12 (3):R99. Epub 2010 May 20. PMID: 20487535

    zur Publikation
  • Increased levels of BLyS and sVCAM-1 in anti-neutrophil cytoplasmatic antibody (ANCA)-associated vasculitides (AAV).

    Schneeweis C, Rafalowicz M, Feist E, Buttgereit F, Rudolph PE, Burmester GR, Egerer K. Clin Exp Rheumatol. 2010 Jan-Feb; 28 (1 Suppl 57):62-6. PMID: 20412705

    zur Publikation
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    Renger F, Bang H, Feist E, Fredenhagen G, Natusch A, Backhaus M, Burmester GR, Egerer K. Arthritis Res Ther 2010; 12(3):R120. Epub 2010 Jun 22. PMID: 20569500

    zur Publikation
  • Cerebral Aspergillus Infections and Meningitis.

    Schwartz S. In Aspergillosis: From Diagnosis to Prevention (Hrsg. Pasqualotto AC). S. 835-52. Springer 2010.

  • Cytogenetic studies in acute leukemia patients relapsing after allogeneic stem cell transplantation.

    Schmidt-Hieber M, Blau IW, Richter G, Türkmen S, Bommer C, Thiel G, Neitzel H, Stroux A, Uharek L, Thiel E, Blau O. Cancer Genet Cytogenet. 2010;198(2):135-43. PMID: 20362228

    zur Publikation
  • BCR-ABL positive cells and chronic myeloid leukemia in immune suppressed organ transplant recipients.

    le Coutre P, Reinke P, Neuhaus R, Trappe R, Ringel F, Lalancette M, Hemmati PG, Dörken B, Daniel PT. Eur J Haematol. 2010;84(1):26-33. PMID: 19799626

    zur Publikation
  • Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma.

    Kaiser M, Lamottke B, Mieth M, Jensen MR, Quadt C, Garcia-Echeverria C, Atadja P, Heider U, von Metzler I, Türkmen S, Sezer O. Eur J Haematol. 2010;84:337-44. PMID: 20028416

    zur Publikation
  • Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.

    Gillissen B, Wendt J, Richter A, Richter A, Müer A, Overkamp T, Gebhardt N, Preissner R, Belka C, Dörken B, Daniel PT J Cell Biol. 2010 Mar 22;188(6):851-62. PMID: 20308427

    zur Publikation
  • Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.

    Hemmati PG, Müer A, Gillissen B, Overkamp T, Milojkovic A, Wendt J, Dörken B, Daniel PT. J Mol Med (Berl). 2010;88:609-22. PMID: 20419447

    zur Publikation
  • Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia.

    Burmeister T, Gökbuget N, Schwartz S, Fischer L, Hubert D, Sindram A, Hoelzer D, Thiel E. Haematologica. 2010;95:241-6. PMID: 19713226

    zur Publikation
  • Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrom.

    Krawitz PM, Schweiger MR, Rödelsperger C, Marcelis C, Kölsch U, Meisel C, Stephani F, Kinoshita T, Murakami Y, Bauer S, Isau M, Fischer A, Dahl A, Kerick M, Hecht J, Köhler S, Jäger M, Grünhagen J, de Condor BJ, Doelken S, Brunner HG, Meinecke P, Passarge E, Thompson MD, Cole DE, Horn D, Roscioli T, Mundlos S, Robinson Nat Genet. 2010 Oct; 42(10):827-9.

  • Assessment of monocytic HLA-DR expression in ICU patients: analytical issues for multicentric flow cytometry studies.

    Monneret, G., F. Venet, C. Meisel, and J.C. Schefold Crit Care, 2010. 14(4): p. 432. PMID:20670390

    zur Publikation
  • Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency.

    Picard, C., H. von Bernuth, et al. Medicine (Baltimore), 2010. 89(6): p. 403-25. PMID:21057262

    zur Publikation
  • High-mobility group box-1 protein serum levels do not reflect monocytic function in patients with sepsis-induced immunosuppression.

    Unterwalder, N., C. Meisel, K. Savvatis, B. Hammoud, C. Fotopoulou, H.D. Volk, P. Reinke, and J.C. Schefold Mediators Inflamm, 2010. 2010: p. 745724. PMID:20652004

    zur Publikation
  • Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma.

    Kaiser M, Lamottke B, Mieth M, Jensen MR, Quadt C, Garcia-Echeverria C, Atadja P, Heider U, von Metzler I, Türkmen S, Sezer O. Eur J Haematol, 2010 Apr;84(4):337-44. PMID 20028416

    zur Publikation
  • Cytogenetic studies in acute leukemia patients relapsing after allogeneic stem cell transplantation.

    Schmidt-Hieber M, Blau IW, Richter G, Türkmen S, Bommer C, Thiel G, Neitzel H, Stroux A, Uharek L, Thiel E, Blau O. Cancer Genet Cytogenet, 2010 Apr 15;198(2):135-43. Erratum in: Cancer Genet Cytogenet. 2010 Jul 1;200(1):73. PMID 20362228

    zur Publikation
  • The allergic sensitization in infants with atopic eczema from different countries.

    Benedictis de FM, Franceschini F, Hill D, Naspitz C, Simons FE, Wahn U, Warner JO, Longueville de M (2009) EPAAC Study Group. Allergy. 2009 Feb; 64(2):295-303. PMID: 19133917

    zur Publikation
  • Longitudinal trends of total and allergen-specific IgE throughout childhood.

    Matricardi PM, Bockelbrink A, Grüber C, Keil T, Hamelmann E, Wahn U, Lau S (2009) Allergy. 2009 Jul; 64(7):1093-8. PMID: 19630859

    zur Publikation
  • Dynamic evolution of serum immunoglobulin E to airborne allergens throughout childhood: results from the Multi-Centre Allergy Study birth cohort.

    Matricardi PM, Bockelbrink A, Keil T, Grüber C, Niggemann B, Hamelmann E, Wahn U, Lau S (2009) Clin Exp Allergy. 2009 Oct; 39(10):1551-7. PMID: 19954429

    zur Publikation
  • Relationship between pretreatment specific IgE and the response to omalizumab therapy.

    Wahn U, Martin C, Freeman P, Blogg M, Jimenez P. (2009) Allergy. 2009 Dec; 64(12):1780-7. PMID: 19627273

    zur Publikation
  • A novel enzyme-linked immunosorbent assay using a mixture of human native and recombinant proteinase-3 significantly improves the diagnostic potential for antineutrophil cytoplasmic antibody-associated vasculitis.

    Damoiseaux J, Dähnrich C, Rosemann A, Probst C, Komorowski L, Stegeman CA, Egerer K, Hiepe F, van Paassen P, Stöcker W, Schlumberger W, Tervaert JW. Ann Rheum Dis 2009 Feb;68(2):228-33. PMID: 18375539

    zur Publikation
  • Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis.

    Hoppe B, Häupl T, Egerer K, Gruber R, Kiesewetter H, Salama A, Burmester GR, Dörner T. Ann Rheum Dis. 2009 Jun;68(6):898-903. Epub 2008 Jul 16. PMID: 18633125

    zur Publikation
  • Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients.

    Hanke K, Brückner CS, Dähnrich C, Huscher D, Komorowski L, Meyer W, Janssen A, Backhaus M, Becker M, Kill A, Egerer K, Burmester GR, Hiepe F, Schlumberger W, Riemekasten G. Arthritis Res Ther 2009; 11(1):R22. Epub 2009 Feb 16. PMID: 19220911

    zur Publikation
  • Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort.

    Hanke K, Dähnrich C, Brückner CS, Huscher D, Becker M, Jansen A, Meyer W, Egerer K, Hiepe F, Burmester GR, Schlumberger W, Riemekasten G. Arthritis Res Ther 2009; 11(1):R28. Epub 2009 Feb 21. PMID: 19232127

    zur Publikation
  • The serological diagnosis of rheumatoid arthritis: antibodies to citrullinated antigens.

    Egerer K, Feist E, Burmester GR. Dtsch Arztebl Int 2009 Mar;106(10):159-63 PMID: 19578391

    zur Publikation
  • Expression of proteasomal immunosubunit beta1i is dysregulated in inflammatory infiltrates of minor salivary glands in Sjogren’s syndrome.

    Morawietz L, Martinez-Gamboa L, Scheffler S, Hausdorf G, Dankof A, Kuckelkorn U, Doerner T, Egerer K, Burmester GR, Faustman DL, Feist E. J Rheumatol 2009 Dec;36(12):2694-703. Epub 2009 Oct 15. PMID: 19833746

    zur Publikation
  • Granulocyte macrophage-colony stimulating factor plus interleukin-2 plus alpha-interferon plus 5-fluorouracil in the treatment of metastatic renal cell cancer: induction of CD80/86+ T cells indicates adverse outcome.

    Westermann J, Hecker AC, Flörcken A, Dörken B, Pezzutto A. J Immunother. 2009;32:667-75. PMID: 19483643

    zur Publikation
  • The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.

    Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, Schneider B, Raff T, Reinhardt R, Gökbuget N, Hoelzer D, Thiel E, Marschalek R. Blood. 2009;113:4011-5. PMID: 19144982

    zur Publikation
  • Clinical manifestation of mannose-binding lectin deficiency in adults independent of concomitant immunodeficiency.

    Hoeflich, C., N. Unterwalder, S. Schuett, K. Schmolke, O. Boenisch, M. Hammer, R. Scheufele, D. Michael, H.D. Volk, C. Scheibenbogen, V. von Baehr, and C. Meisel Hum Immunol, 2009. 70(10): p. 809-12. PMID:19580835

    zur Publikation
  • Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.

    Meisel, C., J.C. Schefold, R. Pschowski, T. Baumann, K. Hetzger, J. Gregor, S. Weber-Carstens, D. Hasper, D. Keh, H. Zuckermann, P. Reinke, and H.D. Volk Am J Respir Crit Care Med, 2009. 180(7): p. 640-8. PMID:19590022

    zur Publikation
  • Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis.

    Poehlmann, H., J.C. Schefold, H. Zuckermann-Becker, H.D. Volk, and C. Meisel Crit Care, 2009. 13(4): p. R119. PMID:19604380

    zur Publikation
  • Delayed onset of (severe) combined immunodeficiency (S)CID (T-B+NK+): complete IL-7 receptor deficiency in a 22 months old girl.

    Rossberg, S., K. Schwarz, C. Meisel, S. Holzhauer, J. Kuhl, W. Ebell, V. Wahn, and H. von Bernuth Klin Padiatr, 2009. 221(6): p. 339-43. PMID:19890784

    zur Publikation
  • Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia.

    Kim TD, Türkmen S, Schwarz M, Koca G, Nogai H, Bommer C, Dörken B, Daniel P, le Coutre P. Haematologica, 2010 Apr;95(4):582-8. Epub 2009 Dec 16. PubMed PMID: 20015884

    zur Publikation
  • Primary versus secondary immunoglobulin E sensitization to soy and wheat in the Multi-Centre Allergy Study cohort.

    Matricardi PM, Bockelbrink A, Beyer K, Keil T, Niggemann B, Grüber C, Wahn U, Lau S (2008) Clin Exp Allergy. 2008 Mar; 38(3):493-500. PMID: 18269671

    zur Publikation
  • Use of Phadiatop Infant in diagnosis of specific sensitization in young children with wheeze or eczema.

    Lau S, Nilsson M, Sulser C, Schulz G, Borres MP, Wahn U (2008) Pediatr Allergy Immunol. 2008 Jun; 19(4):337-41. PMID: 18221462

    zur Publikation
  • IgE antibody responses in young children with atopic dermatitis. EPAAC Study Group.

    Wahn U, Warner J, Simons FE, Benedictis de FM, Diepgen TL, Naspitz CK, Longueville de M, Bauchau V (2008) Pediatr Allergy Immunol. 2008 Jun; 19(4):332-6. PMID: 18422892

    zur Publikation
  • Specific IgE serum concentration is associated with symptom severity in children with seasonal allergic rhinitis. Omalizumab Rhinitis Study Group.

    Rolinck-Werninghaus C, Keil T, Kopp M, Zielen S, Schauer U, von Berg A, Wahn U, Hamelmann E (2008) Allergy. 2008 Oct; 63(10):1339-44. PMID: 18782113

    zur Publikation
  • Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.

    Mietzner B, Tsuiji M, Scheid J, Velinzon K, Tiller T, Abraham K, Gonzalez JB, Pascual V, Stichweh D, Wardemann H, Nussenzweig MC. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9727-32. PMID: 18621685

    zur Publikation
  • Autoimmune reactivity against the 20S-proteasome includes immunosubunits LMP2 (beta1i), MECL1 (beta2i) and LMP7 (beta5i).

    Scheffler S, Kuckelkorn U, Egerer K, Dörner T, Reiter K, Soza A, Burmester GR, Feist E. Rheumatology (Oxford) 2008 May; 47(5):622-6. PMID: 18375405

    zur Publikation
  • Celiac antibodies in the diagnostic workup of white matter lesions.

    Paul F, Pfueller CF, Wuerfel JT, Egerer K, Tanczos B, Baumgart DC, Zipp F. Neurology 2008 Jul 15; 71(3):223-5. PMID: 18625970

    zur Publikation
  • SIT and TRIM determine T-cell fate in the thymus.

    Koelsch U, Schraven B, Simeoni L J. Immunology; Journal of Immunology, 2008, 181: 5930–5939

  • Pyogenic bacterial infections in humans with MyD88 deficiency.

    Von Bernuth, H., C. Picard, Z. Jin, et al. Science, 2008. 321(5889): p. 691-6. PMID:18669862

    zur Publikation
  • Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma.

    Jakob C, Egerer K, Liebisch P, Türkmen S, Zavrski I, Kuckelkorn U, Heider U, Kaiser M, Fleissner C, Sterz J, Kleeberg L, Feist E, Burmester GR, Kloetzel PM, Sezer O. Blood. 2007 Mar 1;109(5):2100-5. Epub 2006 Nov 9. PubMed PMID: 17095627.

    zur Publikation
  • Evaluation of the overall degree of sensitization to airborne allergens by a single serologic test: implications for epidemiologic studies of allergy.

    Matricardi PM, Nisini R, Biselli R, D’Amelio R (1994) J Allergy Clin Immunol. 1994 Jan; 93(1 Pt 1):68-79. PMID: 8308184

    zur Publikation
  • The use of Phadiatop in mass-screening programmes of inhalant allergies: advantages and limitations.

    Matricardi PM, Nisini R, Pizzolo JG, D’Amelio R (1990) Clin Exp Allergy. 1990 Mar; 20(2):151-5. PMID: 2357615

    zur Publikation